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Neuroimaging Studies

Huntington's Disease Center at Johns Hopkins

We have conducted a series of clinical studies to define the course and progression of Huntington’s disease in patients. We have used volumetric structural MRI imaging to show the steady atrophy of the caudate and putamen of the striatum in the basal ganglia, the main area affected in HD, and have proposed that this measure may be a useful biomarker for clinical trials. More recently we have shown structural change begins well before the onset of HD in gene positive presymptomatic individuals. Our data have helped to provide the background for the multi-center PREDICT HD study (see Clinical Trials). We are currently using functional MRI and diffusion tensor imaging (DTI) measures to demonstrate functional changes and changes in white matter connectivity very early in the presymptomatic gene positive population.

Click here for the Psychiatric Neuroimaging Division.

For research information, please contact:

Kia Ultz
Research Program Coordinator
Johns Hopkins University
600 N. Wolfe Street, Meyer 2-181
Baltimore, MD 21287

(410) 955-1349 desk
(410) 955-8233 fax


Johns Hopkins Huntington's Disease SUPPORT GROUP

For those concerned about all aspects of Huntington’s disease: individuals, family, friends

Meets at 7PM
2nd Tuesday of the month at College Manor AL
300 W. Seminary Ave.
Lutherville-Timonium, MD 21093

410-252-0440 (for changes due to inclement weather only)

Enter the building through the infirmary entrance at the back of the building.

Call for instructions: 443-838-7120

Call Kit McFarlane, facilitator, for directions and questions:

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Dr. Ross
The Hunt for Huntington's



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