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Neuroimaging Studies

Baltimore Huntington's Disease Center

We have conducted a series of clinical studies to define the course and progression of Huntington’s disease in patients. We have used volumetric structural MRI imaging to show the steady atrophy of the caudate and putamen of the striatum in the basal ganglia, the main area affected in HD, and have proposed that this measure may be a useful biomarker for clinical trials. More recently we have shown structural change begins well before the onset of HD in gene positive presymptomatic individuals. Our data have helped to provide the background for the multi-center PREDICT HD study (see Clinical Trials). We are currently using functional MRI and diffusion tensor imaging (DTI) measures to demonstrate functional changes and changes in white matter connectivity very early in the presymptomatic gene positive population.

Click here for the Psychiatric Neuroimaging Division.


For research information, please contact:

Gregory Churchill
Research Program Coordinator
Johns Hopkins University
600 N. Wolfe Street, Meyer 2-181
Baltimore, MD 21287

(410) 955-1349 desk
(410) 955-8233 fax

gchurch3@jhu.edu
 

 

For information about viewing the HDSA Webinars at a different time, call or email the social worker, Kit McFarlane at 410-955-2497 or cmcfarl1@jhmi.edu


Johns Hopkins / HDSA
SUPPORT GROUP

For those concerned about all aspects of Huntington’s Disease: individuals, family, friends

Meets at 7PM
2nd Tuesday of the month at Calvary Baptist Church
120 W. Pennsylvania Ave.
Towson, MD 21204

Park in back; go in the basement.
Call Kit McFarlane, facilitator, for directions and questions:

410-955-2497


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Dr. Ross
The Hunt for Huntington's

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