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Clinical Trials

Huntington's Disease Center at Johns Hopkins

Clinical trials are conducted of experimental treatments for Huntington's disease (HD). Studies of medications are usually double-blind and placebo-controlled, that is pills are either the test drug or a placebo and neither the doctor nor the patient knows which is which. Studies are often conducted under the auspices of the Huntington Study Group. Other therapeutic trials may be sponsored by pharmaceutical and biotechnology companies or the National Institute of Health. The Center has conducted a number of trials on its own, including studies of vitamin E and the antiexcitotoxic agent idebenone. Studies currently enrolling include:

Longitudinal Core Study

The Longitudinal Core Study was designed to observe people over the entire course of the neurodegenerative diseases, such as HD. Participants receive yearly neurological and psychological evaluations, and bi-annual magnetic resonance imaging (MRI) scans. The neurological evaluations assess the amount of functional impairment an individual has. The psychological evaluations determine the person's current level of cognitive (intellectual) functioning. Finally, the MRIs are conducted to look for structural changes that occur in the brain over time.

COMING SOON - More information about clinical trials including LEGATO-HD and ENROLL-HD


For research information, please contact:

Kia Ultz
Research Program Coordinator
Johns Hopkins University
600 N. Wolfe Street, Meyer 2-181
Baltimore, MD 21287

(410) 955-1349 desk
(410) 955-8233 fax

kcarte23@jhmi.edu