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Deep Brain Stimulation

Deep brain stimulation (DBS) is an emerging treatment option that is showing promise in clinical trials for mood and cognitive disorders such as major depression and Alzheimer’s disease.Electrodes are implanted in specific regions targeting the underlying cause of the disease. Several target sites for stimulation have been proposed for the treatment of refractory depression.

PET imaging studies on depressed patients have shown that DBS can reverse pretreatment blood flow changes much like antidepressant medication. However, it is not currently FDA approved for depression or bipolar disorder as it is for essential tremor, Parkinson’s disease, dystonia, and chronic and severe obsessive-compulsive disorder, which is the first DBS psychiatric indication to receive FDA approval.

To learn more about DBS for treating obsessive-compulsive disorder, please contact the OCD program



RESEARCH VOLUNTEERS NEEDED - Clinical Trial of TMS with Mood Stabilizers in Bipolar Depression
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Download PDF file of Electroconvulsive Therapy Today, an in-depth article from the Johns Hopkins Depression and Anxiety Bulletin.


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