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Healthy Research Volunteers Needed

SEE ALL RESEARCH VOLUNTEER RECRUITMENT NOTICES

Healthy Adults  |  Healthy Children

ADULTS

Molecular Brain Imaging of Nicotinic Cholinergic Receptors in Normal Aging, Mild Cognitive Impairment and Alzheimer’s Disease
Our study uses a new molecular imaging method designed to visualize distribution of certain nicotinic acetylcholine receptors in the brain. Past research suggests that these nicotinic acetylcholine receptors are reduced in number in the human brain over normal aging and in patients with Mild Cognitive Impairment (MCI) and Alzheimer’s Disease. We aim to visualize the distribution of these receptors in the brain by using a novel radiotracer that targets the α4β2 nicotinic acetylcholine receptor by using positron emission tomography (PET).  Use of this new, sensitive medical imaging technology may help us to better understand how deficits in cognition may be linked to loss of these receptors over aging and in disease--and inform development of new therapies to target these receptors to possibly improve symptoms.  We are recruiting patients with MCI and Alzheimer's Disease as well as healthy controls between the ages 35-90 years. This brain imaging study consists of a 90 minute PET scan, a MRI scan, and blood work across 2 to 3 study visits.  Volunteers are compensated for their time. For more information and to undergo a phone screening to determine eligibility please contact: Dr. Jennifer Coughlin, Co-Investigator: jcoughl2@jhmi.edu; 443-287-4701. PI: Martin G. Pomper, M.D., Ph.D. IRB # NA_00076249

Research on Brain Imaging of Cognition
We are looking for people to participate in a research study that uses functional magnetic resonance imaging (fMRI) to investigate brain function during cognition.  Studies require three visits, with 3-5 hours time required per visit.  You will be compensated up to $225 for your time. To be eligible to participate, you must: * Be 30-60 years old * Be a native speaker of English (i.e., have learned English before the age of 5) * Be right handed * Complete a screening interview to ensure eligibility. For more information on fMRI see our Web page: http://www.jhu.edu/nimlab. For more information on participating and to sign up, click on the “Participate” link, or call 410-502-2184.  You can also email us at jhu.nimlab@gmail.com. We look forward to hearing from you! Johns Hopkins Protocol Number: NA_00039502. Principal Investigator: John E. Desmond, Ph.D., (410) 502-2184.

Functional Neuroimaging of Nimodipine in Healthy Men
The Lieber Institute for Brain Development is recruiting healthy men between ages of 18-35 for a research study conducted at Johns Hopkins Hospital. The study involves a screening visit (about 2 hours) followed by 2 all-day (8am-4pm) study visit days at the participant's choosing. The study investigates the neural effects of Nimodipine, a safe FDA-approved calcium channel blocker, on brain function. During the screening visit, participants will have blood drawn to determine their genotype corresponding to a specific calcium channel gene, and participants will  be grouped by genetic variants for comparison of fMRI activity. Study visit days include IV placement, fMRI scans, cognitive and emotional tasks and blood draws. Candidates must be Caucasian, right-handed, non-smoking and generally healthy. Candidates must not have past or present psychiatric disorders, any metal in the body, history of low blood pressure or loss of consciousness. Compensation is $500 for completion of both study visits with lunch provided during both study days. Call 443-287-5675 or email pharmteam@libd.org for more information. PI: Kristin Bigos, Ph.D. (IRB #: NA_00070426) DOWNLOAD FLYER

Brain and Appetite Research Study: Neurobehavioral Influences on Body Weight in Adolescents
Johns Hopkins Hospital is conducting a research study in adolescents (14-18 y old) and their biological mothers. The study involves three visits for 3-3.5 hours each. Study includes fMRI scan (adolescent only), body composition measurements (height, weight, waist), questionnaires, computer tasks, liquid and buffet meals, and saliva collection. Compensation is up to $245, plus $10 travel costs for each visit. Adolescent candidates must be 14-18 y old, must not be pregnant, claustrophobic or have any metal implants. All candidates must speak English fluently and not have any major medical or psychiatric conditions. Candidates must not have any food or nut allergies or be on any medications affecting weight or appetite. Contact information: Call 410-955-5099 or email lbenson9@jhmi.edu. PI: Susan Carnell, PhD (IRB #: NA_00092328) DOWNLOAD FLYER

Predicting Post-Operative Pain and Analgesic Use: The Role of Endogenous Opioids|
Dr. Claudia Campbell of Johns Hopkins School of Medicine is recruiting people with and without arthritis of the knee. You may join the study if you are at least 45 years old, do not have a serious heart condition or certain other health conditions, and are not on certain types of medications. If you are eligible to participate and want to take part in the study, you will be scheduled for two sessions. Both sessions will involve injecting saline and naloxone through an IV.  Naloxone is FDA approved and frequently used in studies like this. While no adverse effects are associated with naloxone, it may reduce or intensify the other sensations or cause mild nausea or headache.  However, in people taking drugs, especially opioid drugs (like morphine or codeine) naloxone can cause severe withdrawal symptoms and can be very, very dangerous.  Therefore, we will be taking a urine sample at each study visit and drug testing it to make sure it is safe for you to participate. Both sessions will involve sensory testing procedures (heat, cold and pressure) and request blood samples. The study provides compensation (up to $225) and reimbursement for parking and lunch will be provided. Principal Investigator: Dr. Claudia Campbell, office: 410-550-7989, email: ccampb41@jhmi.edu  (IRB Protocol No.: NA_00041113)

Does Your Sense of Taste Affect Your Appetite?
Healthy participants between the ages of 18 and 65 are needed to take part in a research study at Johns Hopkins Bayview Medical Center. The study will examine participants' appetite and ability to taste before and after taking a drug. Participation involves one screening visit and three study days that may last up to five hours each. Participants will earn up to $180. For more information or to enroll, please call 410-550 -1102. Refer to the "Taste" study. Principal Investigator: Denis Antoine, M.D.( Application #: NA_00046407)

Healthy Volunteers/Adult ADD/ADHD
Healthy men and women are needed to take part in a 2-day outpatient study at the Johns Hopkins School of Medicine. Volunteers should be between the ages of 18 and 40 and in good general health. The study involves neuropsychological questionnaires and brain imaging scans. Testing will take place at the Johns Hopkins Hospital and Bayview Medical Center. Volunteers will be paid for completion of all study procedures. Earn up to $300 plus travel expenses. For more information please call 410-550-6266 or 410-550-2588 or email johnshopkins.lab@gmail.com. Principal Investigator: Una D. McCann, M.D. (IRB Number: NA_00073552) Download flyer

Healthy Volunteers/Methamphetamine Users
Healthy men and women are needed for a 4-day inpatient study. Volunteers should be between the ages of 18-45 and in good general health. The study involves neuropsychological questionnaires and brain imaging scans. Testing will take place at Johns Hopkins Bayview Medical Center and Johns Hopkins Hospital. Volunteers will be paid for completion of all study procedures. Earn up to $450 plus travel expenses. For more information please call 410-550-6266 or 410-550-2588 or email johnshopkins.lab@gmail.com. Principal Investigator: Una D. McCann, M.D. (IRB Number: NA_00031313) Download flyer

Oral Glucose Tolerance Test for Alzheimer’s Disease Biomarker Development
The purpose of this research is to find if there is a relationship between a chemical in the blood, which may be related to memory problems, and the body’s hormonal response from the pancreas, gut, and fat tissue after an oral glucose tolerance test. People with and without memory problems may join this study. The study involves a memory screening test and an oral glucose tolerance test. The results of these tests will help us with our research study related to memory, aging, and hormones. If you are interested in learning more about this study please call Jane Pollutra 410-550-4258. Esther Oh, M.D., Principal Investigator (JHU IRB Application No.: NA_00014837)

Insomnia/Healthy Control
Healthy volunteers are needed for a research study conducted at Johns Hopkins to study sleep and sensory testing. To participate, you must be 50 years or older and have no other major health conditions. Parking, and tests are provided at no cost. Compensation is provided. Call 410.550.7906. Principal Investigator: Michael T. Smith, Ph.D.. (IRB Protocol # NA_000118021) Click here for PDF flyer.

Knee Osteoarthritis/Healthy Control
Healthy Volunteers are needed for a research study conducted at Johns Hopkins to study sleep and sensory testing. To participate, you must be 50 years or older, have osteoarthritis of the knee with knee pain and have no other major health conditions. Parking, and tests are provided at no cost. Compensation is provided. Call 410.550.7906. Principal Investigator: Michael T. Smith, Ph.D.. (IRB Protocol # NA_000118021) Click here for PDF flyer.

Good Sleeper/Healthy Control
Healthy Volunteers are needed for a research study conducted at Johns Hopkins to study sleep and sensory testing. To participate you must be 50 years or older and have no other major medical conditions. Parking, and tests are provided at no cost. Compensation is provided. Call 410.550.7906. Principal Investigator: Michael T. Smith, Ph.D.. (IRB Protocol # NA_000118021) Click here for PDF flyer.

Healthy Adult Female Volunteers
We are seeking female subjects (18 yrs old and older) to participate in an outpatient research study. This study requires you to drink a chocolate shake, place your hand in an ice bath, and have your blood drawn. Participation involves an initial 30 min screening and two (approx. 3.5 hours each) morning sessions. You will be paid up to $120 for your participation. For more information call Dr. Colleen Schreyer- 410-955-3863 or email at cclarki1@jhmi.edu. Principal Investigator: Angela S. Guarda, M.D. (NA_00032632)

PET Scans of Healthy Volunteers Over 60 Years of Age
We are conducting brain imaging research using a technique called Positron Emission Tomography, or PET for short, to take pictures of the brain. If you are in good health and aren’t taking medications that affect the brain, you may qualify for participation. Qualified people will participate at no cost to them. Compensation for time and transportation will be provided. For more information, please call: (410) 550-9052. Principal Investigator:
Gwenn Smith, PhD (IRB Protocol No: NA_00021615). Click here for a copy of our flyer.

Sleep and Pain of Healthy Adults - Ages 50-100
Volunteers are needed for a research study conducted at Johns Hopkins to study sleep and sensory testing. To participate, you must be 50 years or older and have no other major medical conditions. Parking and tests are provided at no cost. Compensation is provided. Call 410.550.7906 and/or visit the website. Principal Investigator: Michael T. Smith, Ph.D. Protocol NA_000118021 Click here for a flyer

Healthy Adults with Knee Osteoarthritis - Ages 50-100
Volunteers are needed for a research study conducted at Johns Hopkins to study SLEEP in patients with osteoarthritis of the knee. To participate, you must be 50 years or older. Good sleepers are needed. Parking and tests are provided at no cost. Compensation is provided. Call 410.550.7906 and/or visit the website. Principal Investigator: Michael T. Smith, Ph.D. Protocol NA_000118021 Click here for a flyer

CHILDREN

Brain and Appetite Research Study: Neurobehavioral Influences on Body Weight in Adolescents
Johns Hopkins Hospital is conducting a research study in adolescents (14-18 y old) and their biological mothers. The study involves three visits for 3-3.5 hours each. Study includes fMRI scan (adolescent only), body composition measurements (height, weight, waist), questionnaires, computer tasks, liquid and buffet meals, and saliva collection. Compensation is up to $245, plus $10 travel costs for each visit. Adolescent candidates must be 14-18 y old, must not be pregnant, claustrophobic or have any metal implants. All candidates must speak English fluently and not have any major medical or psychiatric conditions. Candidates must not have any food or nut allergies or be on any medications affecting weight or appetite. Contact information: Call 410-955-5099 or email lbenson9@jhmi.edu. PI: Susan Carnell, PhD (IRB #: NA_00092328) DOWNLOAD FLYER

Eating and Impulsivity Study - Children aged 8–14 years
We are recruiting children between the ages of 8 and 14 years to participate in a study examining impulsivity (whether kids act before they think), eating behavior and weight. The study involves a single visit, lasting from 4 to 6 hours. The visit includes a diagnostic interview, psychological testing, weight and height measurement. Testing is free. Reimbursement for time and inconvenience is $100; parking voucher provided. For more information please contact Principal Investigator Shauna P. Reinblatt, M.D. at 410-550-9947.  (IRB Protocol # NA_00020561).

Iron Status and ADHD - Children ages 6–10
Dr. Rhoda Gottfried and colleagues at the Kennedy Krieger Institute are recruiting children between the ages of 6 and 10, with and without ADHD, to participate in a research study investigating Iron Status, Limb Movements, and ADHD. What to expect from participating: 1) One diagnostic interview, 2) One blood draw, 3) Brief Neurocognitive testing, 4) Three nights of wearing a device that measures leg movement. What are the benefits to participants? Participants receive a summary of the neurocognitive evaluation including an IQ score and laboratory results.Reimbursement for time and inconvenience is $100. Those interested in participation should contact research assistant Kyla Machell at 410-614-3317 or PI Rhoda Gottfried at 410-614-3469. (IRB Protocol #NA_00030898).Click here for PDF flyer.

Emotional Attention and Memory in Healthy Children
We are searching for healthy, typically developing children ages 7 to 17 and their parents to take part in a research study at the Kennedy Kreiger Institute/Johns Hopkins Hospital. Participation involves a psychological evaluation with the parent and child, a brief measurement of the child's IQ, and a computer test to see how children react to different faces and words. The study requires one two and half hour visit. There are no direct benefits to the child for participating in this study. There are no significant medical risks associated with the study. Roma Vasa, M.D. is the principal investigator. Call 443-923-2643. Click here for a PDF flyer. (IRB Protocol # NA_00004616)

Children With and Without ADHD - Ages 4–5
Dr. Mark Mahone and colleagues at the Kennedy Krieger Institute are recruiting children 4 or 5 years old to participate in a research study on learning and brain development in young children. We are looking for boys and girls with and without signs ADHD. The study involves two 3-hour visits of IQ, language, and behavioral tests, a Magnetic Resonance Imaging (MRI) scan of the brain, and behavioral practice sessions for MRI. None of these tests are harmful or painful. All testing is done free of charge. Participants receive a free summary of developmental testing, a picture of your child’s brain, and $50.00. For more information about this study, please contact Lisa Ferenc at (443) 923-4469 or by email (ferenc@kennedykrieger.org). Download Flyer (IRB protocol #NA_00012868)

Neurology of Deficient Response Control in ADHD--Children With and Without ADHD - Ages 8–12  (MRI Research Study of Executive Functioning)
Dr. Stewart Mostofsky and colleagues at the Laboratory of Neurocognitive and Imaging Research at Kennedy Krieger Institute are recruiting children between the ages of 8 and 12 years to participate in a research study of attention, response planning and inhibitory control.  This study is examining the brain basis of ADHD in children. We are looking for boys and girls with ADHD as well as children who do not have ADHD to participate as “comparison subjects”.  The study involves paper and pencil tasks, computer activities and a Magnetic Resonance Imaging (MRI) of the brain. None of these tests are harmful or painful.  There are no direct medical benefits from taking part in the study.  The study involves two days of testing and MRI.  Participants will receive $100.00 and a picture of their brain.  Parents will receive a report of the IQ test administered to their child.  All testing is done free of charge. For more information about this study, please contact Mary Martinelli at 443-923-9258 or Kristie Sweeney at (443) 923-9254 or by email LNIR@kennedykrieger.org.  (IRB protocol #NA_00027428)

Motor Skill Learning in Autism: Assessment and Treatment of Altered Patterns of Learning - Ages 8-12
Dr. Stewart H. Mostofsky of the Kennedy Krieger Institute and Johns Hopkins School of Medicine is recruiting children with and without high-functioning autism between 8 and 12 years of age to participate in a study of attention, learning, memory, and motor skills. The study involves paper and pencil tasks, computer activities, and MRI scan of the brain. None of the tests are harmful or painful and are done free of charge. There are no direct medical benefits for participating in the study. The duration of the study is two to three days. Participants will receive a $100 check and a picture of their brain. Parents will receive a report summarizing the IQ testing administered to their child. For more information about this study, please contact Alyssa Tiedemann at (443) 923-9263 or LNIR@kennedykrieger.org (IRB Protocol # NA_00027073)

Anomalous Motor Physiology in ADHD: Inhibitory and Reward Mechanisms – Ages 8-12
Dr. Stewart H. Mostofsky of the Kennedy Krieger Institute and Johns Hopkins School of Medicine is recruiting children with and without Attention Deficit Hyperactivity Disorder (ADHD) between 8 and 12 years of age to participate in a research study of attention, learning, memory, reward response, and motor skills.  The study involves paper and pencil tasks, computer activities, transcranial magnetic stimulation (TMS, a painless, non-invasive brain stimulation technique), an EEG, and a MRI scan of the brain. A single dose of medication that influences reward systems in the brain may also be given to your child.  None of the tests are harmful or painful and are done free of charge.  There are no direct medical benefits for participating in the study.  The duration of the study is one to two days. Participants will receive a $50 check for each day of study participation and a picture of their brain.  Parents will receive a report summarizing the IQ testing administered to their child.  For more information about this study, please contact Kristie Sweeney at (443) 923-9254 or LNIR@kennedykrieger.org. (IRB # NA_00044909)

NOTICE TO RESEARCHERS: If you are faculty in the Department of Psychiatry and Behavioral Sciences and you wish to post a recruitment ad on this page, please contact Donna Mennitto at dmennit2@jhmi.edu. You will need to send the IRB-approved recruitment language in paragraph form with a title of the study, the PI, contact information and the IRB Protocol Number. If you wish to make a flyer available to the public, send it in PDF or Word document form. You are responsible for IRB approval of the ad. Please be sure to contact us to remove the ad from this page when recruitment is complete. Thank you.

 

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