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Functional Magnetic Resonance Imaging (fMRI)

Division of Psychiatric Neuroimaging

Functional magnetic resonance imaging (fMRI) is used to visualize brain function, by visualizing changes in chemical composition of brain areas or changes in the flow of fluids that occur over timespans of seconds to minutes.

BOLD (Blood Oxygenation Level Dependent) fMRI operates on the principle that hemoglobin is diamagnetic when oxygenated but paramagnetic when deoxygenated. The contrast between oxygenated and deoxygenated hemoglobin can be used as an indicator of cerebral blood flow to areas with increased neural activity.

Learn More About fMRI

Functional Magnetic Resonance Imaging User's Guide
Yassa, M., Johns Hopkins University School of Medicine (2005).

Localization of Brain Function with Magnetic Resonance Imaging
Cohen, M., Bookheimer, S. Trends in Neurosciences 17(7), 1994.

The Basics of MRI
Hornak, J., University of Rochester (2002).

fMRI Training Courses

Statistical Parametric Mapping Course
FIL at UCL, London, UK

FSL & Freesurfer Course
FMRIB, Oxford and HST/MGH, Boston, MA

Functional Magnetic Resonance Imaging Course
FIRC at MCW, Milwaukee, WI

fMRI Processing and Analysis Packages


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