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Schulze, Thomas G., M.D.
Professor of Psychiatric Genetics
University of Erlangen-Nuremberg (Germany), the University of Barcelona (Catalonia, Spain), UNC at Chapel Hill, NC, and Wake Forest University, Winston-Salem, NC
University of Erlangen-Nuremberg (Germany)
Residency in Adult Psychiatry
University of Bonn (Germany)
University of Chicago, Chicago, IL & NIMH
Residency in Adult Psychiatry and Senior Staff Scientist
Central Institute of Mental Health, Mannheim, Germany
Dr. Schulze’s research focuses on genotype–phenotype relationship in bipolar disorder and related psychiatric disorders. To study the genetic basis of response to lithium treatment in bipolar disorder, he has organized the international Consortium on Lithium Genetics (www.ConLiGen.org). Dr. Schulze is furthermore interested in the development of novel statistical tools to perform such studies in a systematic fashion.
Schulze TG, Zhang K, Chen Y-S, Akula N, Sun F, McMahon FJ. Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome. Hum Mol Genet 2004; 13:335-342.
Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidman V, Kovalenko S, Abou Jamra R, Becker T, Leszczynska-Rodziewicz A, Hauser J, Illig T, Klopp N, Wellek S, Cichon S, Henn FA, McMahon FJ, Maier W, Propping P, Nöthen MM, Rietschel M. Genotype-phenotype studies in bipolar disorder show association between the DAOA/G30 locus and persecutory delusions: A first step towards a molecular genetic classification of psychiatric phenotypes. Am J Psychiatry 2005; 162:2101-2108.
Schulze TG, Hedeker D, Zandi P, Rietschel M, McMahon FJ, What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics. Arch Gen Psychiatry 2006; 63:1368-1376.
Rietschel M, Beckmann L, Strohmaier J, Georgi A, Karpushova A, Schirmbeck F, Boesshenz KV, Schmael C, Buerger C, Abou Jamra R, Schumacher J, Hoefels S, Kumsta R, Entringer S, Krug A, Markov V, Maier W, Propping P, Wuest S, Kircher T, Noethen MM, Cichon S, Schulze TG. G72 and its association with major depression and neuroticism in large population-based groups from Germany. Am J Psychiatry 2008; 165:753-762.
Schulze TG, Detera-Wadleigh SD, Akula N, Gupta A, Kassem L, Steele J, Pearl J, Strohmaier J, Breuer R, Schwarz M, Propping P, Nöthen MM, Cichon S, Schumacher J;NIMH Genetics Initiative Bipolar Disorder Consortium7, Rietschel M, McMahon FJ. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry. 2009; 14:487-491.