Schulze, Thomas G., M.D.

Assistant Professor

Main Office Address

The Johns Hopkins Mood Disorders Center
Johns Hopkins Hospital
600 N. Wolfe Street, Meyer 3-181
Baltimore, MD 21287

Phone: 202-758-8130
Fax: 301-402-9081

E-mail: Thomas_G_Schulze@jhu.edu

Education

1990-1997	Medical Student	University of Erlangen-Nuremberg (Germany), the University of Barcelona (Catalonia, Spain), UNC at Chapel Hill, NC, and Wake Forest University, Winston-Salem, NC
1997	M.D.	University of Erlangen-Nuremberg (Germany)
1997-2000	Residency in Adult Psychiatry	University of Bonn (Germany)
2000-2002	Postdoctoral Fellowship	University of Chicago, Chicago, IL & NIMH
2003-2007	Residency in Adult Psychiatry and Senior Staff Scientist	Central Institute of Mental Health, Mannheim, Germany

Professional Interests

Dr. Schulze’s research focuses on genotype–phenotype relationship in bipolar disorder and related psychiatric disorders. To study the genetic basis of response to lithium treatment in bipolar disorder, he has organized the international Consortium on Lithium Genetics (www.ConLiGen.org). Dr. Schulze is furthermore interested in the development of novel statistical tools to perform such studies in a systematic fashion.

Selected Publications

Schulze TG, Zhang K, Chen Y-S, Akula N, Sun F, McMahon FJ. Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome. Hum Mol Genet 2004; 13:335-342.

Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidman V, Kovalenko S, Abou Jamra R, Becker T, Leszczynska-Rodziewicz A, Hauser J, Illig T, Klopp N, Wellek S, Cichon S, Henn FA, McMahon FJ, Maier W, Propping P, Nöthen MM, Rietschel M. Genotype-phenotype studies in bipolar disorder show association between the DAOA/G30 locus and persecutory delusions: A first step towards a molecular genetic classification of psychiatric phenotypes. Am J Psychiatry 2005; 162:2101-2108.

Schulze TG, Hedeker D, Zandi P, Rietschel M, McMahon FJ, What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics. Arch Gen Psychiatry 2006; 63:1368-1376.

Rietschel M, Beckmann L, Strohmaier J, Georgi A, Karpushova A, Schirmbeck F, Boesshenz KV, Schmael C, Buerger C, Abou Jamra R, Schumacher J, Hoefels S, Kumsta R, Entringer S, Krug A, Markov V, Maier W, Propping P, Wuest S, Kircher T, Noethen MM, Cichon S, Schulze TG. G72 and its association with major depression and neuroticism in large population-based groups from Germany. Am J Psychiatry 2008; 165:753-762.

Schulze TG, Detera-Wadleigh SD, Akula N, Gupta A, Kassem L, Steele J, Pearl J, Strohmaier J, Breuer R, Schwarz M, Propping P, Nöthen MM, Cichon S, Schumacher J;NIMH Genetics Initiative Bipolar Disorder Consortium7, Rietschel M, McMahon FJ. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry. 2009; 14:487-491.

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