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Sawa, Akira, M.D., Ph.D.

Dr. Akira Sawa

Professor
Director, Schizophrenia Center
Director, Conte Center

Director, Program in Molecular Psychiatry

Main Office Address

Meyer 3-166A
The Johns Hopkins Hospital
600 North Wolfe St.
Baltimore, MD 21287

Phone: 410-955-4726
Fax: 410-614-1792

E-mail: asawa1@jhmi.edu

Administrative Assistant

Yukiko Lema
E-mail: ylema1@jhmi.edu
Phone: 410-614-5238

Education

1990

M.D.

Univ. of Tokyo (Japan)

1990-96

Residency, Clinical Fellow, Ph.D. in Psychiatry

Univ. of Tokyo (Japan)

1996-2001

Postdoctoral Research Fellowship

Johns Hopkins University (Neuroscience)

Professional Interests

Schizophrenia and bipolar disorder: pathogenesis at the molecular level

Hopkins BrainWise Newsletter articles about Dr. Sawa's work:

Selected Publications

Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A. Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Mol Psychiatry, 2012 (in press).Link

Kondo M, Sawa A. Anti-/Propsychotic drug signaling via heteromeric GPCRs--a balancing act? Cell, 147:964-965 (2011). Link

Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, Houslay MD, Katsanis N, Sawa A. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature, 473:92-96 (2011) Link

Brandon NJ, Sawa A. Linking neurodevelopmental and synaptic theories via DISC1. Nature Rev Neurosci, 12:707-722 (2011) Link

Tajinda K, Ishizuka K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella, NG. Neuronal biomarkers from patients with mental illnesses: a novel method through nasal biopsy combined with laser-captured microdissection. Mol. Psychiatry. 15:231-232 (2010) Link

Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, Dunlop AJ, Makiko Y, Seshadri AJ, Ishizuka K, Srivastava DP, Xie Z, Baraban JM, Houslay MD, Tomoda T, Brandon NJ, Kamiya A, Yan Z, Penzes P, Sawa A.  Disrupted-in-Schizophrenia-1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nature Neurosci., 13:327-332 (2010) Link

 

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