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Rudnicki, Dobrila, Ph.D.

Assistant Professor

Main Office Address

CMSC 8-121
The Johns Hopkins Hospital
600 North Wolfe St.
Baltimore, MD 21287

Phone: 410-502-4654
Fax: 410-614-0013


Administrative Assistant

Eileen Kasda
E-mail :



Bsc in Biochemistry and Microbiology

King’s College, University of London, UK


PhD in Neurogenetics

University of Aachen, Germany


Postdoctoral Research Fellowship

National Human Genome Research Institute, Bethesda


Postdoctoral Research Fellowship

Johns Hopkins University School of Medicine  (Psychiatry)

Professional Interests

Cellular and molecular pathogenesis of neuropsychiatric disorders, in particular Huntington’s disease-like 2 (HDL2), Huntington’s disease (HD) and schizophrenia.

Click here for a Hopkins Brain Wise Newsletter article about Dr. Rudnicki's work

Selected Publications

Rudnicki, D.D., Margolis, R.L., Pearson, E.C., and Krzyzosiak, W.J. (2012) Diced triplets expose neurons to RISC. PLOS Genet, 8(2):e1002545. Epub 2012 Feb 23.

Wilburn.,  B., Rudnicki, D.D., Zhao, J., Weitz, T.M.,  Cheng, Y., Xiaofeng Gu, X.,  Greiner, E., Park, C. S., Wang, N., Sopher, B. L., La Spada, A. R., Alex Osmand, A.,  Margolis, R. L.,  Sun, Y. E.,  and Yang, X. W. (2011) A Novel Antisense CAG Repeat Transcript at JPH3 Locus Mediating Expanded Polyglutamine Protein Toxicity in Huntington's Disease-Like 2 (HDL2) Mice, Neuron , 12, 427-40.

Chung, D.W., Rudnicki, D.D., Lan, Y. and Margolis, R.L. (2011) A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression. Hum Mol Gen. 20 (17), 3467-77.

Rudnicki, D.D., Pletnikova, O., Vonsattel, J.P., Ross, C.A., Margolis, R.L. (2008) A Comparison of Huntington Disease and Huntington Disease-Like 2 Neuropathology. (2008) J Neuropathol Exp Neurol. 67, 366-74.

Rudnicki, D.D., Holmes, S.E., Lin, M.W., Thornton, C.A., Ross, C.A. and Margolis, R.L. (2007) Huntington's disease-like 2 is associated with CUG repeat-containing RNA foci. Ann Neurol 61, 272-82.

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