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Ross, Christopher, M.D., Ph.D.

Dr. Christopher Ross

Professor of Psychiatry, Neurology and Neuroscience
Director, Division of Neurobiology
Director, Molecular Neurobiology Laboratory
Director, Baltimore Huntington's Disease Center

Main Office Address

CMSC 8-121
600 North Wolfe Street
Baltimore, MD 21287

Phone: 410-614-0011
Fax: 410-614-0013

E-mail: cross@jhmi.edu


Administrative Assistant

Tricia Baker
Phone: 443-287-4962
E-Mail: tperret1@jhmi.edu


Education

1975

B.A.

Princeton University

1983

M.D.

Cornell Medical College

1983

Ph.D., Neurobiology

Cornell University Graduate School

1983-84

Mixed Medicine/Psychiatry
Internship

Baltimore City Hospital

1984-1987

Psychiatry Residency

Johns Hopkins Hospital


Professional Interests

In their study of neuropsychiatric disorders, Dr. Ross and his research team focus on Huntington's disease and Parkinson's disease, and use insights from these disorders to approach more complex diseases such as schizophrenia. They use biophysical and biochemical techniques, cell models, and transgenic mouse models to understand disease processes and provide targets for development of rational therapeutics. Ultimately, the neurobiologic study of schizophrenia many help illuminate normal thought, perception and emotion – and help us understand the biology of human nature itself.

See Division of Neurobiology and Laboratory of Molecular Neurobiology

Click here and here for Hopkins Brain Wise Newsletter articles about Dr. Ross' work


Selected Publications

Ross CA, Margolis RL, Reading SA, Pletnikov M, Coyle JT. Neurobiology of schizophrenia. Neuron. 2006 Oct 5;52(1):139-53.

Smith WW, Pei Z, Jiang H, Dawson VL, Dawson TM, Ross CA. Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nature Neurosci. 2006 Oct;9(10):1231-3.

Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18676-81.

Ross CA, Poirier MA. Protein aggregation and neurodegenerative disease. Nature Medicine 2004 Jul;10 Suppl:S10-7.

Nucifora  FC Jr, Sasaki M, Peters MF, Huang H, Cooper JK, Yamada M, Takahashi H, Tsuji S, Troncoso J, Dawson VL, Dawson TM, Ross CA. Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity. Science. 2001 Mar 23;291(5512):2423-8.

 

 
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