Pickar, David, M.D.

Professor

Off Campus Address

Gabriel Pharma
6500 Seven Locks Road, Suite 220
Cabin John, MD 20818

Phone: 301-263-1313

E-mail: dpickar@gabrielpharma.com

Administrative Assistant

Catherine Pikar
E-mail: dpickar@gabrielpharma.com
Phone 301-263-1313

Education and Government Service

Professional Interests

Neuropsychpharmacology with emphasis on schizophrenia and pharmacogenetics; new drug develoopment for treatment of psychosis; dopaminergic system activity; candidate genes for psychosis.

Selected Publications

Pickar D, Labarca R, Linnoila M, Roy A, Hommer D, Everett D, Paul SM:  Neuroleptic-induced decrease in plasma homovanillic acid and antipsychotic activity in schizophrenic patients.  Science 1984;225:954-957. 

Pickar D, Litman RE, Hong WW, Su TP, Weissman EM, Hsiao JK, Potter WZ:  Clinical Response to clozapine in patients with schizophrenia.  Arch Gen Psychiatry 1994;51:159-160. 

Pickar D, Su T-P, Weinberger D, Coppola R, Malhotra AK, Knable MB, Lee KS, Gorey J, Bartko JJ, Breier A, Hsiao J:  Individual variation in D2 dopamine receptor occupancy in clozapine-treated patients.  Am J Psychiatry 1996;153:1571-1578. 

Pickar D, Rubinow K:  Pharmacogenomics of Psychiatric Disorders.  Trends in Pharmacological Sciences, Vol.22 No.2 February 2001, Elsevier Science London.  

Pickar D and Bartko JJ.  Effect size of symptom status in withdrawal of typical antipsychotics and subsequent clozapine treatment in schizophrenic patients.  American Journal of Psychiatry, 2003; 160:1133-1138.