Little, John I., M.D.

Assistant Professor

Main Office Address

Phipps 300B
The Johns Hopkins Hospital
600 North Wolfe St.
Baltimore, MD 21287-5371

Phone: 410-614-5995 
Fax: 410-624-3676

E-mail: jlittle1@jhmi.edu

Administrative Assistant

La'Mar Dixon
Phone: 410-955-6699
E-mail:ldixon26@hotmail.com

Education

Professional Interests

Structural and functional brain imaging to examine treatment response variability and underlying illness pathophysiology in geriatric affective disorders.  Geriatric psychopharmacology; particularly clinical trials for patients with late-life affective disorders or AlzheimerÆs disease.

Selected Publications

 Little JT, Ketter TA, Kimbrell TA, Danielson A, Benson BE, Willis MW, Post RM: Venlafaxine or bupropion responders but not nonresponders show baseline prefrontal and paralimbic hypometabolism compared to controls.  Psychopharmacol Bull, 32(4):629-635, 1996. 

Little JT, Johnson DN, Minichiello M, Weingartner H, Sunderland T:  Combined nicotinic and muscarinic blockade in elderly normal volunteers: cognitive, behavioral, and physiologic responses.  Neuropsychopharmacology, 19:60-69, 1998.