Kamiya, Atsushi, M.D., Ph.D.

Assistant Professor Schizophrenia Center Molecular Psychiatry Program Atsushi Kamiya Lab Office Address Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine 600 North Wolfe Street Meyer 3-146 Baltimore MD 21287 Phone : 410-502-0060 Fax: 410-614-1792 E-mail: akamiya1@jhmi.edu

Education

Professional Interests

Role of genetic risk factors for psychiatric disorders in brain development

Selected Publications

Kamiya, A., Kubo, K., Tomoda, T., Takaki, M., Youn, R., Ozeki, Y., Sawamura, N., Park, U., Kudo, O., Okawa, M., Ross, C.A., Hatten, M.E., Nakajima, K., Sawa, A.: Disrupted-in-Schizophrenia-1 is required for neuronal migration in the cerebral cortex: perturbation by schizophrenia-associated mutation.  Nature Cell Biol., 7; 1167-1178 (2005) (highlighted as “ 10 major breakthroughs in 2005 in Science 310: 1880-1885 2005”) 

Kamiya, A., Tomoda, T., Chang, J., Takaki, M., Zhan, C., Morita, M., Cascio, M.B., Elashvili, S., Koizumi, H., Takanezawa, Y., Dickerson, F., Yolken, R., Arai, H., Sawa, A.: DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.  Hum. Mol. Genet. 15; 3313-3323 (2006)

Kamiya, A., Tan, P.L., Kubo, K., Engelhard, C., Ishizuka, K., Kubo, A., Tsukita, S.,  Pulver, A. E., Nakajima, K., Cascella, N. G., Katsanis, N., Sawa, A.: PCM1 is recruited to the centrosome by the cooperative action of DISC1 and BBS4 and is a candidate for psychiatric illness.  Arch. Gen. Psychiatry 65; 996-1006 (2008)

Niwa, M.^*, Kamiya, A*., Murai, R., Kubo, K., Gruber, A., Lu, L., Seshadri, S., Hiyama, H., Jaaro-Peled, H., Noda, Y., Cascella, N., O’donnell, P., Nakajima, K., Sawa, A., Nabeshima, T.: Transient knockdown of DISC1 in the developing cerebral cortex leads to dopaminergic disturbance and schizophrenia deficits in young adult mice.  *These authors contributed equally to this work.  Neuron 65; 480-489 (2010)   

Zoubovsky, SP, Pogorelov, VM, Taniguchi, Y, Kim, S, Yoon, P, Nwulia, E, Sawa, A, Pletnikov, MV, Kamiya, A.: Working memory deficits in neuronal nitric oxide synthase knockout mice: potential impairments in prefrontal cortex mediated cognitive function.  Biochem Biophys Res Commun 408; 707-712 (2011). 

Taniguchi, Y, Young-Pearse, T, Sawa, A, Kamiya, A.: In utero electroporation as a tool for genetic manipulation in vivo in order to study psychiatric disorders: from genes to circuits and behaviors.  Neuroscientist 2011 May 5 [Epub ahead of print].