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Photo of Dr. Anthony Ross Cammarato, PhD

Anthony Ross Cammarato, PhD

Assistant Professor
Assistant Professor of Medicine

See Research on Pubmed

Male

Titles

  • Assistant Professor
  • Assistant Professor of Medicine

Centers & Institutes

  • Heart and Vascular Institute

Research Interests

Identifying and manipulating age- and mutation-dependent modifiers of cardiac function; Identifying and manipulating age- and mutation-dependent modifiers of cardiac function; Hierarchical modeling and imaging of contractile machinery; Integrative analysis of striated muscle performance; Myopathic processes

Biography

Dr. Anthony Cammarato is an Assistant Professor of Medicine in the Cardiology Department. He studies the identification and manipulation of age- and mutation-dependent modifiers of cardiac function, hierarchical modeling and imaging of contractile machinery, integrative analysis of striated muscle performance and myopathic processes.

Dr. Cammarato holds a bachelor’s degree from Mary Washington College and a PhD from the Boston University School of Medicine. He completed a postdoctoral fellowship at San Diego State University and worked as a staff scientist and later as an assistant research professor at the Sanford-Burnham Medical Research Institute before joining the Johns Hopkins faculty in 2011. He is a member of the American Physiological Society, the Biophysical Society, the American Society for Cell Biology and the Genetics Society of America. 

Languages

  • English

Memberships

Member, The American Physiological Society 

Member, Biophysical Society 

Member, The American Society for Cell Biology 

Member, Genetics Society of America

Additional Resources +
  • Education +

    Education

    • Ph.D., Boston University School of Medicine, Boston, MA, 2004
    • B.S.N., Mary Washington College, Fredericksburg, VA, 1995, Biology

    Fellowships

    • San Diego State University, San Diego, CA, 2008, Postdoctoral Fellow, Molecular Genetics, Structural Biology, Cardiac Function
  • Research & Publications +

    Selected Publications View all on PubMed

    1. Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell. 2014 Jan 9. doi: 10.1111/acel.12193. [Epub ahead of print]
    2. Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A. A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. Circ Res. 2014 Jan 17;114(2):e6-17. doi: 10.1161/CIRCRESAHA.114.302028. Epub 2013 Nov 12. Erratum in: Circ Res. 2014 Feb 14;114(4):e28. 
    3. Xie HB, Cammarato A, Rajasekaran NS, Zhang H, Suggs JA, Lin HC, Bernstein SI, Benjamin IJ, Golic KG. The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster. PLoS Genet. 2013 Jun;9(6):e1003544. doi: 10.1371/journal.pgen.1003544. Epub 2013 Jun 20. 
    4. Wang Y, Melkani GC, Suggs JA, Melkani A, Kronert WA, Cammarato A, Bernstein SI. Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness. Mol Biol Cell. 2012 Jun;23(11):2057-65. doi: 10.1091/mbc.E12-02-0120. Epub 2012 Apr 11. 
    5. Kaushik G, Fuhrmann A, Cammarato A, Engler AJ. In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium. Biophys J. 2011 Dec 7;101(11):2629-37. doi: 10.1016/j.bpj.2011.10.042.

    Lab

    The Cammarato Lab is located in the Division of Cardiology in the Department of Medicine at The Johns Hopkins University School of Medicine. We are interested in basic mechanisms of striated muscle biology. We employ an array of imaging techniques to study “structural physiology” of cardiac and skeletal muscle. Drosophila melanogaster, the fruit fly, expresses both forms of striated muscle and benefits greatly from powerful genetic tools. We investigate conserved myopathic (muscle disease) processes and perform hierarchical and integrative analysis of muscle function from the level of single molecules and macromolecular complexes through the level of the tissue itself.

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    Professional Activities

      

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    Department/Division

    • Medicine - Cardiovascular

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