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Rosanne Rouf, MD

Assistant Professor of Medicine
Appointment Phone


Main Location

The Johns Hopkins Hospital

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Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

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International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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  • Assistant Professor of Medicine

Centers & Institutes

  • Comprehensive Transplant Center
  • Heart and Vascular Institute


Cardiac Transplant, Cardiomyopathy, Cardiovascular Disease, Congestive Heart Failure, Heart Failure, Heart Transplant, Inherited Heart Diseases, Peripartum Cardiomyopathy

Research Interests

The role of matricellular proteins in modulating cardiac fibrosis and heart failure


Dr. Rosanne Rouf is a cardiologist with expertise in the medical care of heart failure and heart transplant patients. Her research interests include the role of gene expression in heart failure and in heart defects related to Marfan and Loeys-Deitz syndromes.

Dr. Rouf received her undergraduate and master’s degrees in electrical engineering and computer science from the Massachusetts Institute of Technology. She graduated from the Duke University School of Medicine, and completed her residency at the Tufts Medical Center. Dr. Rouf pursued fellowships at Tufts and Johns Hopkins, joining the faculty of the Johns Hopkins School of Medicine in 2011.


  • English
  • Bengali


2006-present: American Heart Association

Additional Resources

Additional Resources +
  • Education +


    • Duke University School of Medicine (Durham NC ) (2002)


    • Tufts - New England Medical Center Hospitals / Internal Medicine (Boston MA ) (2005)


    • Johns Hopkins University School of Medicine / Cardiology (Baltimore MD ) (2010)
    • Tufts - New England Medical Center Hospitals (Boston MA ) (2006)


    • Internal Medicine, American Board of Internal Medicine (2005)
  • Research & Publications +

    Selected Publications

    Gallo EM, Loch DC, Habashi JP, Calderon JF, Chen Y, Bedja D, van Erp C, Gerber EE, Parker SJ, Sauls K, Judge DP, Cooke SK, Lindsay ME, Rouf R, Myers L, Ap Rhys CM, Kent KC, Norris RA, Huso DL, Dietz HC. Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest. 2014 Jan 2;124(1):448-60.

    Gould RA, Sinha R, Aziz H, Rouf R, Dietz HC 3rd, Judge DP, Butcher J. Multi-scale biomechanical remodeling in aging and genetic mutant murine mitral valve leaflets: insights into Marfan syndrome. PLoS One. September 11, 2012; 7(9):e44639.

    Wei H, Bedja D, Koitabashi N, Xing D, Chen J, Fox-Talbot K, Rouf R, Chen S, Steenbergen C, Harmon JW, Dietz HC, Gabrielson KL, Kass DA, Semenza GL. Endothelial expression of hypoxia inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGFb signaling. Proceedings of the National Academy of Sciences. March 8, 2012.

    Judge DP, Rouf R, Habashi J, Dietz HC. Mitral valve disease in Marfan syndrome and relate disorders. Journal of Cardiovascular Translational Research. August 25, 2011.

    Judge DP, Rouf R. Use of genetics in the clinical evaluation and management of heart failure. Current Treatment Options in Cardiovascular Medicine. December 2010; 12(6):566-77.

    Blaha MJ, Bansal S, Rouf R, Golden SH, DeFilippis AP, Blumenthal RS. A practical ‘ABCDE’ approach to treating the metabolic syndrome. Mayo Clinic Proceedings. August 2008; 83(8):932-41.

    Rouf R, Greytak S, Wooten EC, Wu J, Boltax J, Picard M, Dillman WH, Patten RD, Huggins GS. Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription. Circulation Research. August 29, 2008;102(5):493-501.

    Mudd JO, Borlaug BA, Johnston PV, Kral BG, Rouf R, Blumenthal RS, Kwiterovich PO, Jr. BeyondLDL Cholesterol—Defining the role of LDL heterogeneity in coronary artery disease. Journal of American College of Cardiology. October 30, 2007; 50:1735-1741.

  • Academic Affiliations & Courses +
  • Activities & Honors +


    1999 – 2000: Stanley J. Sarnoff Fellowship (one of 10 cardiovascular full-time research fellowships nationally awarded in 1999; awarded 2nd year of fellowship award in 2000)

    2005: Heart Failure Society of America Travel Grant

    2005: NIH/NRSA Post-doctoral Research Fellowship, Molecular Cardiology Research Institute

    2007: Council on Clinical Cardiology Fellowship Travel Grant, American Heart Association

    2008: Case Study Finalist, Mechanical Circulatory Support in Advanced Heart Failure Conference

    2008: Women in Cardiology Trainee Award for Excellence, American Heart Association

    2009: Sarnoff Scholar Fellow-to-Faculty Transition Award (4-year award; one awarded nationally every two years)

    2010: Stanley L. Blumenthal Cardiology Research Award, First Prize in Basic Science

    2011: W. W. Smith Heart Research Award

    2011: International Congress of Human Genetics Young Investigator Award

    2012: Johns Hopkins University School of Medicine Clinician Scientist Award (1 of 5 awarded institutionally in 2012)

    Professional Activities

    2009-2011: AHA Council on Clinical Cardiology, Women in Cardiology Committee

  • Videos & Media +

    Lectures and Presentations

    “Interrogation of sex differences in myxomatous mitral valve disease.” Annual Scientific Meeting of the Leducq MITRAL Transatlantic Consortium. December 9-10 2010, Boston, MA.

    “Fibrillin-1 is an active extracellular entity necessary for normal cardiac function.” 31st Annual Scientific Meeting of the Stanley J. Sarnoff Endowment for Cardiovascular Science. April 28-30 2011, National Harbor, Maryland.

    “Gender influences mitral valve disease and response to therapy in Marfan mice.” Annual Scientific Meeting of the Leducq MITRAL Transatlantic Consortium. June 2-3 2011, Madrid, Spain.

    “TAC’kling Marfan Cardiomyopathy: Novel insights regarding pathogenesis and treatment of heart failure.” Division of Cardiology Grand Rounds, Johns Hopkins Hospital. March 21 2012, Baltimore, MD.

  • Events +
  • Contact & Locations +


    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 443-287-6720
    Appointment Phone: 443-997-0270
    Location Map


    • Medicine - Cardiology

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