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Ashley Marie Cimino-Mathews, M.D.

Photo of Dr. Ashley Marie Cimino-Mathews, M.D.

Assistant Professor of Pathology


Languages: English, Spanish

Expertise: Pathology

Research Interests: Breast stromal neoplasms; Pathogenesis of breast cancer metastasis


The Johns Hopkins Hospital

401 North Broadway
Weinberg Building, Suite 2242
Baltimore, MD 21231-2410 map


Dr. Ashley Cimino-Mathews is an assistant professor of pathology and oncology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include general surgical pathology and breast pathology. She joined the Breast Pathology Service at Johns Hopkins in July 2012.

Dr. Cimino-Mathews obtained her B.S. degree with highest honors from Emory University, where she studied breast cancer tumor vaccine development. She received her M.D. from Weill Cornell Medical College, followed by a residency in anatomic and clinical pathology at The Johns Hopkins Hospital.

Dr. Cimino-Mathew's ongoing research interests include breast cancer immunotherapy, the pathogenesis of breast cancer metastasis, and breast stromal neoplasms.

She is strongly committed to women's health care and breast cancer research. Her numerous awards for scholarship and research include Phi Beta Kappa, Alpha Omega Alpha, the Weill Cornell "Good Physician" Award, the 4th Annual Safeway Breast Cancer Retreat Runner-up Poster Award in 2011 and the Johns Hopkins Pathology Young Investigator's Day Top Prize in Clinical in 2011, a Career Development Award in 2013, the Pathology Housestaff Anatomic Pathology Teaching Award in 2014, and acceptance into the Emerging Women's Leadership Program in 2015. more


  • Assistant Professor of Pathology
  • Assistant Professor of Oncology



  • MD, Weill Cornell Medical College (2008)


  • Johns Hopkins University School of Medicine / Pathology (2012)

Board Certifications

  • American Board of Pathology / Pathology- Anatomic or Clinical (2012)

Research & Publications

Research Summary

Dr. Cimino-Mathew's research focuses on the breast cancer tumor microenvironment and immunotherapy, the pathogenesis of breast cancer metastasis, and breast stromal neoplasms.

Selected Publications

View all on Pubmed

Cimino-Mathews A, Ye X, Meeker A, Argani P, Emens LA. Metastatic Triple Negative Breast Cancers at First Relapse Have Fewer Tumor-Infiltrating Lymphocytes Than Their Matched Primary Breast Tumors: A Pilot Study. Human Pathol. 2013 Oct;44:2055-63.

Cimino-Mathews A, Sharma R, Illei PB, Vang R, Argani P. A Subset of Malignant Phyllodes Tumors Express p63 and p40: A Diagnostic Pitfall in Breast Core Needle Biopsies. Amer J Surg Pathol. 2014 Dec;38(12):1689-96.

Cimino-Mathews A, Foote JB, Emens LA. Immune targeting in breast cancer. Oncology (Williston Park). 2015 May;29:375-85.

Cimino-Mathews A, Thompson E, Taube JM, Ye X, Lu Y, Meeker A, Xu H, Sharma R, Lecksell K, Cornish TC, Cuka N, Argani P, Emens LA. PD-L1 (B7-H1) Expression and the Immune Tumor Microenvironment in Human Primary and Metastatic Breast Carcinomas. Hum Pathol. 2016 Jan;47(1):52-63.

Thompson E, Taube JM, Elwood H, Sharma R, Meeker A, Warzecha HN, Argani P, Cimino-Mathews A*, Emens LA*. The Immune Microenvironment of Breast Ductal Carcinoma in Situ. Mod Pathol. 2016 Mar;29(3):249-58. *Co-senior corresponding authors.

Activities & Honors


  • Weill Cornell "Good Physician"
  • Award, Alpha Omega Alpha
  • Phi Beta Kappa
  • Young Investigator’s Day Top Prize in Clinical, Johns Hopkins Pathology , 2011
  • Runner-up Poster Award, 4th Annual Safeway Breast Cancer Retreat, 2011
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