The Johns Hopkins Hospital
600 N. Wolfe Street
The John G. Rangos Sr. Building Suite 248
Baltimore, MD 21287
Amyotrophic Lateral Sclerosis, Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIPD), Muscular Dystrophies, Myasthenia Gravis, Myopathy, Neurology, Neuromuscular Pathology, Peripheral Neuropathies
The role of astrocytes in ALS
Dr. Lyle Ostrow sees patients with a broad range of diseases of nerve and muscle, including amyotrophic lateral sclerosis (ALS), chronic inflammatory polyneuropathy (CIDP), peripheral neuropathies, muscular dystrophies and myopathies, myositis, and myasthenia gravis.
Dr. Ostrow's laboratory research focuses on the role of astrocytes in amyotrophic lateral sclerosis (ALS) and other neurologic disorders. He is investigating whether abnormally increased production of a protein called endothelin by astrocytes may represent a novel therapeutic target in ALS. He also studies ways in which astrocytes sense and respond to mechanical stress, and how this may be involved in several neurologic diseases.
Dr. Lyle Ostrow received his M.D. degree and a Ph.D. in Biophysics from the State University of New York at Buffalo. He completed an Internal Medicine Internship at Johns Hopkins Bayview Medical Center, followed by Neurology Residency training at The Johns Hopkins Hospital. After residency, Dr. Ostrow completed a fellowship in Neuromuscular Medicine also at Johns Hopkins.