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Pranita D Tamma, MD

Director, Pediatric Antimicrobial Stewardship Program
Assistant Professor of Pediatrics
Main Location

The Johns Hopkins Hospital

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  • Director, Pediatric Antimicrobial Stewardship Program
  • Assistant Professor of Pediatrics


Infectious Disease, Pediatric Emergency Medicine

Research Interests

Improving antimicrobial use among children; Prevention of healthcare-associated infections


Pranita Tamma is an Assistant Professor of Pediatric Infectious Diseases at Johns Hopkins Hospital and Director of the Pediatric Antimicrobial Stewardship Program. She completed her medical school training at The Downstate Medical School in Brooklyn, New York and her pediatric residency and fellowship at Johns Hopkins Hospital. As Director of Antimicrobial Stewardship, she assists clinicians with optimizing the selection, route, dose, interval, and frequency of antibiotics, developing guidelines to guide the appropriate and judicious use of antibiotics, and monitoring patient outcomes after implementation of these practices. Her research focuses on clinical outcomes related to antibiotic administration strategies in both children and adults and the incorporation of rapid diagnostics to assist with the early optimization of antibiotic therapy. She is particularly interested in determining optimal therapy for infections caused by multi-drug resistant Gram-negative organisms.


  • English
  • Spanish


Society for Healthcare Epidemiology of America

The Pediatric Infectious Diseases Society

Additional Resources +
  • Education +


    • Johns Hopkins Bloomberg School of Public Health (Baltimore MD ) (2011)
    • SUNY at Brooklyn College of Medicine (Brooklyn NY ) (2004)


    • Johns Hopkins University School of Medicine / Pediatrics (Baltimore MD ) (2007)


    • Johns Hopkins University School of Medicine / Pediatric Infectious Diseases (Baltimore MD ) (2011)


    • American Board of Pediatrics / Pediatrics (2007)
  • Research & Publications +

    Selected Publications

    1: Tamma PD, Holmes A, Dodds Ashley E. Antimicrobial stewardship: another focus for patient safety? Curr Opin Infect Dis. 2014 Jun 19. [Epub ahead of print] PubMed PMID: 24945612.

    2: Tschudin-Sutter S, Tamma PD, Milstone AM, Perl TM. The Prediction of
    Complicated Clostridium difficile Infections in Children. Infect Control Hosp
    Epidemiol. 2014 Jul;35(7):901-3. doi: 10.1086/676874. Epub 2014 May 20. PubMed PMID: 24915226.

    3: Tamma PD, Srinivasan A, Cosgrove SE. Infectious Disease Clinics of North
    America. Antimicrobial stewardship. Preface. Infect Dis Clin North Am. 2014
    Jun;28(2):xi-xii. doi: 10.1016/j.idc.2014.04.001. PubMed PMID: 24857396.

    4: Tamma PD, Sklansky DJ, Palazzi DL, Swami SK, Milstone AM. Antibiotic
    Susceptibility of Common Pediatric Uropathogens in the United States. Clin Infect Dis. 2014 May 13. pii: ciu360. [Epub ahead of print] PubMed PMID: 24825869.

    5: Huang Y, Carroll KC, Cosgrove SE, Tamma PD. Determining the optimal
    ceftriaxone MIC for triggering extended-spectrum β-lactamase confirmatory
    testing. J Clin Microbiol. 2014 Jun;52(6):2228-30. doi: 10.1128/JCM.00716-14.
    Epub 2014 Apr 16. PubMed PMID: 24740077; PubMed Central PMCID: PMC4042788.

    6: Sick AC, Tschudin-Sutter S, Turnbull AE, Weissman SJ, Tamma PD. Empiric
    Combination Therapy for Gram-Negative Bacteremia. Pediatrics. 2014 Apr 7. [Epub ahead of print] PubMed PMID: 24709936.

    7: Drekonja DM, Beekmann SE, Elliott S, Mukundan D, Polenakovik H, Rosenthal ME, Tamma PD, Polgreen PM, Weissman SJ. Challenges in the management of infections due to carbapenem-resistant Enterobacteriaceae. Infect Control Hosp Epidemiol. 2014 Apr;35(4):437-9. doi: 10.1086/675604. PubMed PMID: 24602953.

    8: Hsu AJ, Tamma PD. Treatment of multidrug-resistant Gram-negative infections in children. Clin Infect Dis. 2014 May;58(10):1439-48. doi: 10.1093/cid/ciu069. Epub 2014 Feb 5. PubMed PMID: 24501388.

    9: Tamma PD, Robinson GL, Gerber JS, Newland JG, DeLisle CM, Zaoutis TE, Milstone AM. Pediatric antimicrobial susceptibility trends across the United States. Infect Control Hosp Epidemiol. 2013 Dec;34(12):1244-51. doi: 10.1086/673974. Epub 2013 Oct 28. PubMed PMID: 24225608.

    10: Tschudin-Sutter S, Tamma PD, Milstone AM, Perl TM. Predictors of first
    recurrence of Clostridium difficile infections in children. Pediatr Infect Dis J.
    2014 Apr;33(4):414-6. doi: 10.1097/INF.0000000000000108. PubMed PMID: 24168983.

    11: Park SH, Milstone AM, Diener-West M, Nussenblatt V, Cosgrove SE, Tamma PD. Short versus prolonged courses of antibiotic therapy for children with
    uncomplicated Gram-negative bacteraemia. J Antimicrob Chemother. 2014
    Mar;69(3):779-85. doi: 10.1093/jac/dkt424. Epub 2013 Oct 24. PubMed PMID:

    12: Tschudin-Sutter S, Tamma PD, Naegeli AN, Speck KA, Milstone AM, Perl TM.
    Distinguishing community-associated from hospital-associated Clostridium
    difficile infections in children: implications for public health surveillance.
    Clin Infect Dis. 2013 Dec;57(12):1665-72. doi: 10.1093/cid/cit581. Epub 2013 Sep 17. PubMed PMID: 24046303.

    13: Tamma PD, Turnbull AE, Harris AD, Milstone AM, Hsu AJ, Cosgrove SE. Less is more: combination antibiotic therapy for the treatment of gram-negative
    bacteremia in pediatric patients. JAMA Pediatr. 2013 Oct;167(10):903-10. doi:
    10.1001/jamapediatrics.2013.196. PubMed PMID: 23921724.

    14: Tamma PD, Tan K, Nussenblatt VR, Turnbull AE, Carroll KC, Cosgrove SE. Can matrix-assisted laser desorption ionization time-of-flight mass spectrometry
    (MALDI-TOF) enhance antimicrobial stewardship efforts in the acute care setting? Infect Control Hosp Epidemiol. 2013 Sep;34(9):990-5. doi: 10.1086/671731. Epub 2013 Jul 25. PubMed PMID: 23917918.

    15: Tamma PD, Girdwood SC, Gopaul R, Tekle T, Roberts AA, Harris AD, Cosgrove SE, Carroll KC. The use of cefepime for treating AmpC β-lactamase-producing Enterobacteriaceae. Clin Infect Dis. 2013 Sep;57(6):781-8. doi:
    10.1093/cid/cit395. Epub 2013 Jun 11. PubMed PMID: 23759352.

    16: Popoola VO, Tamma P, Reich NG, Perl TM, Milstone AM. Risk factors for
    persistent methicillin-resistant Staphylococcus aureus colonization in children
    with multiple intensive care unit admissions. Infect Control Hosp Epidemiol. 2013 Jul;34(7):748-50. doi: 10.1086/670994. Epub 2013 May 22. PubMed PMID: 23739081; PubMed Central PMCID: PMC3684074.

    17: Tamma PD, Sandora TJ. Clostridium difficile Infection in Children: Current
    State and Unanswered Questions. J Pediatric Infect Dis Soc. 2012
    Sep;1(3):230-243. Epub 2012 Jul 26. PubMed PMID: 23687578; PubMed Central PMCID: PMC3656539.

    18: Tamma PD, Powers JH. Do patient data really support the clinical and
    laboratory standards institute recommendation for lowering third-generation
    cephalosporin interpretive breakpoints? Clin Infect Dis. 2013 Aug;57(4):624-5.
    doi: 10.1093/cid/cit308. Epub 2013 May 8. PubMed PMID: 23658433.

    19: Sick AC, Lehmann CU, Tamma PD, Lee CK, Agwu AL. Sustained savings from a longitudinal cost analysis of an internet-based preapproval antimicrobial
    stewardship program. Infect Control Hosp Epidemiol. 2013 Jun;34(6):573-80. doi: 10.1086/670625. Epub 2013 Apr 18. PubMed PMID: 23651887.

    20: Tamma PD, Wu H, Gerber JS, Hsu AJ, Tekle T, Carroll KC, Cosgrove SE. Outcomes of children with enterobacteriaceae bacteremia with reduced susceptibility to ceftriaxone: do the revised breakpoints translate to improved patient outcomes? Pediatr Infect Dis J. 2013 Sep;32(9):965-9. doi: 10.1097/INF.0b013e31829043b3. PubMed PMID: 23470679.

    21: Tamma PD, Newland JG, Pannaraj PS, Metjian TA, Banerjee R, Gerber JS,
    Weissman SJ, Beekmann SE, Polgreen PM, Hersh AL. The use of intravenous colistin among children in the United States: results from a multicenter, case series.Pediatr Infect Dis J. 2013 Jan;32(1):17-22. doi: 0.1097/INF.0b013e3182703790.PubMed PMID: 22935871.

    22: Tamma PD, Cosgrove SE, Maragakis LL. Combination therapy for treatment of infections with gram-negative bacteria. Clin Microbiol Rev. 2012
    Jul;25(3):450-70. doi: 10.1128/CMR.05041-11. Review. PubMed PMID: 22763634; PubMed Central PMCID: PMC3416487.

    23: Tamma PD, Turnbull AE, Milstone AM, Hsu AJ, Carroll KC, Cosgrove SE. Does the piperacillin minimum inhibitory concentration for Pseudomonas aeruginosa influence clinical outcomes of children with pseudomonal bacteremia? Clin Infect Dis. 2012 Sep;55(6):799-806. doi: 10.1093/cid/cis545. Epub 2012 Jun 13. PubMed PMID: 22696019; PubMed Central PMCID: PMC3657512.

    24: Tamma PD, Savard P, Pál T, Sonnevend Á, Perl TM, Milstone AM. An outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit. Infect Control Hosp Epidemiol. 2012 Jun;33(6):631-4. doi:10.1086/665715. Epub 2012 Apr 16. PubMed PMID: 22561722.

    25: Tamma PD, Cosgrove SE. Duration of antibiotic therapy for community-acquired pneumonia in children. Clin Infect Dis. 2012 Mar;54(6):883-4; author reply 885.doi: 10.1093/cid/cir941. Epub 2012 Jan 30. PubMed PMID: 22291108.

    26: Tamma PD, Putcha N, Suh YD, Van Arendonk KJ, Rinke ML. Does prolonged
    β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials. BMC Infect Dis. 2011 Jun 22;11:181. doi: 10.1186/1471-2334-11-181. Review. PubMed PMID: 21696619; PubMed Central PMCID: PMC3141415.

    27: Tamma PD, Agwu AL, Hartman AL. Behavior outbursts, orofacial dyskinesias, and CSF pleocytosis in a healthy child. Pediatrics. 2011 Jul;128(1):e242-5. doi: 10.1542/peds.2010-3504. Epub 2011 Jun 6. PubMed PMID: 21646261; PubMed Central
    PMCID: PMC3124105.

    28: Tamma PD, Turnbull AE, Milstone AM, Lehmann CU, Sydnor ER, Cosgrove SE. Ventilator-associated tracheitis in children: does antibiotic duration matter?
    Clin Infect Dis. 2011 Jun;52(11):1324-31. doi: 10.1093/cid/cir203. Epub 2011 May 2. PubMed PMID: 21540205; PubMed Central PMCID: PMC3097368.

    29: Jenh AM, Tamma PD, Milstone AM. Extended-interval aminoglycoside dosing in pediatrics. Pediatr Infect Dis J. 2011 Apr;30(4):338-9. doi:
    10.1097/INF.0b013e31820f0f3a. Review. PubMed PMID: 21407038.

    30: Tamma PD, Jenh AM, Milstone AM. Prolonged β-lactam infusion for Gram-negative Infections. Pediatr Infect Dis J. 2011 Apr;30(4):336-7. doi:
    10.1097/INF.0b013e31820ef3e5. Review. PubMed PMID: 21407037.

    31: Tamma PD, Cosgrove SE. Antimicrobial stewardship. Infect Dis Clin North Am. 2011 Mar;25(1):245-60. doi: 10.1016/j.idc.2010.11.011. Review. PubMed PMID:21316003.

    32: Cantey JB, Tamma P. Viridans streptococcal meningitis following penetrating cervical injury. Pediatr Emerg Care. 2011 Jan;27(1):34-5. doi:
    10.1097/PEC.0b013e3182045bfb. PubMed PMID: 21206253.

    33: Tofteland ND, Stuart-Hilgenfeld M, Hunt R, Tamma P, Canares TL, Yao-Cohen M, Nazif J. Index of suspicion Pediatr Rev. 2010 Nov;31(11):477-82. doi: 10.1542/pir.31-11-477. PubMed PMID: 21041426.

    34: Tamma PD, Turnbull AE, Milstone AM, Cosgrove SE, Valsamakis A, Budd A, Perl TM. Clinical outcomes of seasonal influenza and pandemic influenza A (H1N1) in pediatric inpatients. BMC Pediatr. 2010 Oct 6;10:72. doi:
    10.1186/1471-2431-10-72. PubMed PMID: 20925926; PubMed Central PMCID: PMC2978207.

    35: Tamma PD, Aucott SW, Milstone AM. Chlorhexidine use in the neonatal intensive care unit: results from a national survey. Infect Control Hosp Epidemiol. 2010 Aug;31(8):846-9. doi: 10.1086/655017. PubMed PMID: 20586654; PubMed Central PMCID: PMC2900383.

    36: Tamma PD, Steinhoff MC, Omer SB. Influenza infection and vaccination in
    pregnant women. Expert Rev Respir Med. 2010 Jun;4(3):321-8. doi:
    10.1586/ers.10.26. Review. PubMed PMID: 20524915.

    37: Tamma P. Vaccines in immunocompromised patients. Pediatr Rev. 2010
    Jan;31(1):38-40. doi: 10.1542/pir.31-1-38. PubMed PMID: 20048039.

    38: Tamma PD, Ault KA, del Rio C, Steinhoff MC, Halsey NA, Omer SB. Safety of
    influenza vaccination during pregnancy. Am J Obstet Gynecol. 2009
    Dec;201(6):547-52. doi: 10.1016/j.ajog.2009.09.034. Epub 2009 Oct 21. Review. PubMed PMID: 19850275.

    39: Tamma PD, Lee CK. Use of colistin in children. Pediatr Infect Dis J. 2009
    Jun;28(6):534-5. doi: 10.1097/INF.0b013e3181ac4980. Review. PubMed PMID:

    40: Strouse JJ, Tamma P, Kickler TS, Takemoto CM. D-dimer for the diagnosis of venous thromboembolism in children. Am J Hematol. 2009 Jan;84(1):62-3. doi: 10.1002/ajh.21311. PubMed PMID: 19006230; PubMed Central PMCID: PMC3977002.

    41: Tamma P. Toxoplasmosis. Pediatr Rev. 2007 Dec;28(12):470-1. Review. PubMed PMID: 18055648.

    42: Tamma P. The galactomannan antigen assay. Pediatr Infect Dis J. 2007
    Jul;26(7):641-2. Review. PubMed PMID: 17596809.

    43: Tamma P, Migeon C, Ghosh D, Loddenkemper T, Wright B, Phillips S, Levien MG, Prayson RA, Hashkes P, Dixon R. Index of suspicion. Pediatr Rev. 2006
    Sep;27(9):351-7. PubMed PMID: 16950941.

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  • Contact & Locations +


    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410 614 1492
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    Johns Hopkins Outpatient Center
    601 N. Caroline Street
    Baltimore, MD 21287
    Phone: 410 614 1492
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