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Jennifer H. Elisseeff, Ph.D.

Director, Translational Tissue Engineering Center
Professor of Ophthalmology

See Research on Pubmed | See Research on Google Scholar



  • Director, Translational Tissue Engineering Center
  • Jules Stein Professor of Ophthalmology
  • Professor of Ophthalmology
  • Joint of Orthopaedic Surgery
  • Professor of Biomedical Engineering

Centers & Institutes

  • Basic Biomedical Sciences, Institute for
  • Translational Tissue Engineering Center
  • Wilmer Eye Institute Research

Research Interests

Regenerative medicine; Biomaterials; Stem cells; Regenerating tissue; Stem cell research; Cartilage regeneration; Biomaterials and stem cells for tissue engineering; Cornea repair


Dr. Jennifer Elisseeff is a professor of ophthalmology and orthopaedic surgery at the Johns Hopkins School of Medicine. She also holds appointments in the Johns Hopkins Department of Chemical and Biological Engineering and Department of Materials Science and Engineering. Her research focuses on tissue regeneration. Dr. Elisseeff is the Jules Stein Professor of Ophthalmology and director of the Translational Tissue Engineering Center.

Her team is engaged in engineering technologies to repair lost tissues. Specifically, she is examining hydrogels as a scaffold for tissue engineering and is working to develop an artificial cornea.

Dr. Elisseeff received a bachelor's degree in chemistry from Carnegie Mellon University and a Ph.D. in medical engineering from the Harvard-MIT Division of Health Sciences and Technology. After doctoral studies, Dr. Elisseeff was a fellow at the National Institute of General Medical Sciences Pharmacology Research Associate Program. She joined the Johns Hopkins faculty in 2001.

In 2004, Dr. Elisseeff cofounded Cartilix Inc., a startup that translated adhesive and biomaterial technologies for treating orthopedic disease, acquired by Biomet Inc. in 2009. In 2009, she also founded Aegeria Soft Tissue and Tissue Repair, startups focused on soft tissue regeneration and wound healing.

Dr. Elisseeff serves on the Scientific Advisory Boards of Bausch and Lomb, Kythera Biopharmaceutical, and Cellular Bioengineering Inc. She has received numerous awards including the Carnegie Mellon Young Alumni Award, Arthritis Investigator Award from the Arthritis Foundation, Yasuda Award from the Society of Physical Regulation in Medicine and Biology. She was named by Technology Review magazine as a top innovator under 35 in 2002 and her research was cited among the top 10 technologies to change the future. In 2008, Dr. Elisseeff was elected a fellow in the American Institute for Medical and Biological Engineering and a Young Global Leader in the World Economic Forum. She has published over 120 articles, book chapters and patent applications and given over 130 national and international invited lectures.


  • English


Biomedical Engineering Society

Materials Research Society

American Association for the Advancement of Science

Orthopedic Research Society

American Chemical Society

International Society for Stem Cell Research

Additional Resources +
  • Education +


    • Ph.D., Harvard-MIT Division of Health Sciences and Technology, Boston, Massachusetts, 1999, Medical Engineering
    • B.S., Carnegie Mellon University, Pittsburgh, PA, 1994, Chemistry


    • National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, 2001, Developmental Biology
  • Research & Publications +

    Research Summary

    Dr. Elisseeff is a leading expert in the field of tissue engineering. She directs the Translational Tissue Engineering Center where she and her team of scientists study stem cells, develop new biomaterials and design new technologies for regenerative medicine.

    Currently, Dr. Elisseeff is working to develop a synthetic cornea using biomaterials. She was recently awarded a grant from the military to develop technologies for ocular battlefield wounds.

    Selected Publications View all on PubMed

    1. Elisseeff J, McIntosh W, Fu K, Blunk BT, Langer R. “Controlled-release of IGF-I and TGF-beta1 in a photopolymerizing hydrogel for cartilage tissue engineering.” J Orthop Res, 2001. 19(6): p. 1098-104.
    2. Elisseeff J, McIntosh W, Anseth K, Riley S, Ragan P, Langer R. “Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi- interpenetrating networks.” J Biomed Mater Res, 2000. 51(2): p. 164-71.
    3. Elisseeff J,Anseth KS, Sims D, McIntosh W, Randolph M, Yaremchuk M, Langer R. “Transdermal photopolymerization of poly(ethylene oxide)-based injectable hydrogels for tissue-engineered cartilage.” Plast Reconstr Surg, 1999. 104(4): p. 1014-22.
    4. Elisseeff J,Anseth KS, Sims D, McIntosh W, Randolph M, Langer R. “Transdermal Photopolymerization for Minimally Invasive Implantation.” Proc. Nat. Acad. Sc., USA, 1999. 96: p. 3104-3107.
    5. Anseth KS, Metters AT, Bryant SJ, Martens PJ, Elisseeff J, Bowman CN. “In situ forming degradable networks and their application in tissue engineering and drug delivery.” J Control Release, 2002. 78(1-3): p. 199-209.


    Dr. Elisseeff is the director of the Translational Tissue Engineering Center, a collaboration between the Department of Biomedical Engineering and Wilmer Eye Institute. The lab comprises surgical fellows, biologists, chemists and engineers who work together to develop new biomaterials, study stem cells and design new technologies for regenerative medicine. The goal of her lab is to engineer technologies to repair lost tissues.

    Her lab is examining hydrogels as a scaffold for tissue engineering. Hydrogels are ideal due to their high water content for nutrient and waste transport, and their ability to encapsulate cells and to implant in a minimally invasive manner. The lab is currently focused on developing synthetic-biological hydrogels with highly controlled physical properties and biological function. The discovery of human embryonic stem cells has created the possibility to regenerate any tissue from a single, totipotent cell population. Her lab is examining the potential of using biomaterials for stem cell differentiation and engineering mesenchymal tissues.

    Translational Tissue Engineering Center:

  • Academic Affiliations & Courses +
  • Activities & Honors +


    Young Global Leader, The World Economic Forum, 2008-2013

    Elected Fellow of American Institute of Medical and Biological Engineering (AIMBE), 2009

    Society for Physical Regulation in Biology and Medicine, Iwao Yasuda Award, 2005

    Young Alumni Award, Carnegie Mellon, 2003

    Nominated to World Technology Network, Medicine Category, 2003

    TR10 Honoree: Ten Technologies that will change the future (Technology Review Magazine), 2003

    TR100 Honoree (Technology Review Magazine) top 100 innovators under age 35, 2002

    Arthritis Investigator Award, Arthritis Foundation, 2001

    Pharmacology Research Associate Fellow, NIGMS, 2000

    Whitaker Scholarship to attend the International Society of Internal Organs, May, 1997, Providence, RI

    Whitaker Scholarship to attend 42nd American Society for Artificial Organs Meeting, May 1996

    Pittsburgh Society of Analytical Chemists University Award, 1994

    Monteverdi Award for top female student in Mellon College of Science, 1994

    Recipient of the Warner Prize for Juniors in Chemistry, 1993

    Professional Activities

    Selected Institutional Administrative Appointments

    Graduate Education Committee, 2009

    ESCRO review committee, 2009 - present

    Stem Cell Bioethics Group, 2009

    Young Inventor’s International Advisor Canada, 2003 - present

    Chair of Academic panel for HST 35th Reunion, 2004

    Hopkins Biotech Network Advisory Board, 2004

    High School Internet Science and Technology Fair Advisor, 2003

    Baltimore Poly High School women serious about science and mentoring program, 2002 - present

    Vice chair, Tissue Characterization, ASTM Tissue Engineered

    Medical Products Standards, 2002

    Member of Harvard-MIT Division of Health Sciences and Technology, Admissions and Graduation Committee, 1997, 1998

    Editorial Activities

    Journal reviews: Biomacromolecules, Biomaterials, FASEB J, J of Dental Research, Tissue Engineering, ASTM, Pharmaceutical Research, PNAS, Annals of Biomedical Engineering, Nature Biotechnology, Journal of Polymer Science, Acta Biomateriala, Journal of the American Chemical Society, Nature, Science

    Editorial board, Tissue Engineering, 2005 - 2009

    Editorial board, International Journal of Medical Implants and Device, 2005


    Co-founder, Aegeria, 2009 - present

    SAB member, Kythera Biopharmaceuticals, CA

    Co-founder and Consultant, Cartilix, Inc., San Carlos, CA, 2004-2009

    SAB member, Bausch and Lomb, Rochester, NY (Pharmaceutical and Vision Care Boards)

    SAB member, CBI Cellular Bioengineering Inc., Honolulu, HA

  • Videos & Media +
  • Events +
  • Contact & Locations +


    • Ophthalmology
    • Biomedical Engineering
    • Orthopaedic Surgery

    For Research Inquiries Contact

    Smith Building 5035
    400 N. Broadway
    Baltimore, MD 21287
    Phone: 410-614-6834
    Fax: 410-614-6840

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