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School of Medicine
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Daniel L.J. Thorek, Ph.D.
Assistant Professor of Radiology and Radiological Science
Research Interests: Molecularly specific imaging agents; alpha particle emitting therapies
- Assistant Professor of Radiology and Radiological Science
- Assistant Professor of Oncology
Centers & Institutes
- B.A., University of Toronto (Canada) (2004)
- Ph.D., University of Pennsylvania (Pennsylvania) (2009)
Memorial Sloan Kettering Cancer Center, New York, New York, 2013, Molecular Imaging in Oncology Fellowship
Research & Publications
The research focus of the Thorek Research Laboratory is on the development and application of quantitative molecular imaging techniques. These tools enhance our ability to detect, characterize and monitor disease, as well as to optimally guide and dose targeted therapies.
Internalization of secreted antigen–targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis. Sci. Transl. Med. 8, 367ra167, 2016. D. L. J. Thorek, P. A. Watson, S.-G. Lee, A. T. Ku, et al.
Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis. Journal of the National Cancer Institute. 2015. Diane Abou, David Ulmert, Michelle Doucet, Robert Hobbs, Ryan Riddle, Daniel LJ Thorek
Cerenkov imaging. Advances in Cancer Research, 2014. S Das, J Grimm, DL Thorek.
Quantitative imaging of disease signatures through radioactive decay signal conversion. Nature Medicine, 2013. Daniel LJ Thorek, Anuja Ogirala, Bradley J Beattie, Jan Grimm.
Positron lymphography: multimodal, high-resolution, dynamic mapping and resection of lymph nodes after intradermal injection of 18F-FDG. Journal of Nuclear Medicine, 2012. Daniel LJ Thorek, Diane S Abou, Bradley J Beattie, Rachel M Bartlett, Ruimin Huang, Pat B Zanzonico, Jan Grimm.
Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells. Biomaterials, 2008. Daniel LJ Thorek, Andrew Tsourkas.