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Sridhar Nimmagadda, Ph.D.

Associate Professor of Radiology and Radiological Science

See Research on Pubmed

Male

Titles

  • Associate Professor of Radiology and Radiological Science
  • Joint of Medicine
  • Associate Professor of Oncology

Centers & Institutes

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Research Interests

Molecular imaging; Metastasis; Chemokine receptors; Monitoring tumor therapeutic response; Probe development

Biography

Dr. Sridhar Nimmagadda is an Assistant Professor in the Johns Hopkins Medicine Department of Radiology and Radiological Science, Department of Oncology and Department of Medicine. He specializes in neuroradiology and molecular imaging.

Dr. Nimmagadda received a B.S. in mathematics, physics and chemistry, and an M.S. in physical chemistry from Andhra University in India. He completed an additional M.S. in bioorganic chemistry at the Indian Institute of Technology, and in 2005 he received a Ph.D. in cancer biology from Wayne State University in Detroit, Michigan. After a postdoctoral fellowship in molecular imaging at the Johns Hopkins University School of Medicine, he joined the Johns Hopkins faculty as an Assistant Professor in 2009.

Dr. Nimmagadda has won numerous awards and grants for his research, has authored more than 50 journal articles, and is the Associate Editor of Frontiers in Cancer Imaging and Diagnosis.

Languages

  • English
Additional Resources +
  • Education +

    Education

    • Ph.D., Wayne State University, Detroit, MI, 2005, Cancer Biology
    • M.S., Indian Institute of Technology, Madras, India, 1999, Bioorganic Chemistry
    • M.S., Andhra University, Visakhapatnam, India, 1996, Physical Chemistry
    • B.S., Andhra University, Visakhapatnam, India, 1994, Mathematics, Physics and Chemistry

    Fellowships

    • Molecular Imaging, Johns Hopkins University, Baltimore, MD, 2008, Postdoctoral Fellowship
  • Research & Publications +

    Research Summary

    Dr. Nimmagadda’s research focuses on the development of imaging agents for early detection of metastatic disease. His current work examines the role of chemokine receptors in cancer progression and metastasis. Ongoing studies include the development and evaluation of positron emission tomography (PET), single photon emission computed tomography (SPECT) based radiopharmaceuticals and optical imaging agents for chemokine receptors four and seven (CXCR4 and CXCR7).

    Selected Publications View all on PubMed

    1. Nimmagadda S, Pullambhatla M, Lisok A, Hu C, Maitra A, Pomper MG. “Imaging Axl expression in pancreatic and prostate cancer xenografts.” Biochem Biophys Res Commun. 2013 Dec 11. pii: S0006-291X(13)02071-8. doi: 10.1016/j.bbrc.2013.12.014. [Epub ahead of print].
    2. Ray Banerjee S, Pullambhatla M, Foss CA, Falk A, Byun Y, Nimmagadda S, Mease RC, Pomper MG. “Effect of chelators on the pharmacokinetics of (99m)Tc-labeled imaging agents for the prostate-specific membrane antigen (PSMA).” J Med Chem. 2013 Aug 8;56(15):6108-21. doi: 10.1021/jm400823w. Epub 2013 Jul 22.
    3. Louissaint NA, Cao YJ, Skipper PL, Liberman RG, Tannenbaum SR, Nimmagadda S, Anderson JR, Everts S, Bakshi R, Fuchs EJ, Hendrix CW. “Single dose pharmacokinetics of oral tenofovir in plasma, peripheral blood mononuclear cells, colonic tissue, and vaginal tissue.” AIDS Res Hum Retroviruses. 2013 Nov;29(11):1443-50. doi: 10.1089/AID.2013.0044. Epub 2013 May 29.
    4. Baba JS, Endres CJ, Foss CA, Nimmagadda S, Jung H, Goddard JS, Lee S, McKisson J, Smith MF, Stolin AV, Weisenberger AG, Pomper MG. “Molecular imaging of conscious, unrestrained mice with AwakeSPECT.” J Nucl Med. 2013 Jun;54(6):969-76. doi: 10.2967/jnumed.112.109090. Epub 2013 Mar 27].
    5. Hosseini-Farahabadi S, Geetha-Loganathan P, Fu K, Nimmagadda S, Yang HJ, Richman JM. “Dual functions for WNT5A during cartilage development and in disease.” Matrix Biol. 2013 Jun 24;32(5):252-64. doi: 10.1016/j.matbio.2013.02.005. Epub 2013 Mar 5.
  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    Berson-Yalow Award, Society of Nuclear Medicine and Molecular Imaging, 2010

    Young Investigator Award, Center for Molecular Imaging Innovation & Translation, 2011

    Berson-Yalow Award, Society of Nuclear Medicine and Molecular Imaging, 2011

    Society of Nuclear Medicine and Molecular Imaging Travel Award, 2008

    Alavi-Mandell Award, Society of Nuclear Medicine and Molecular Imaging, 2008

    World Molecular Imaging Congress, 2008

    Travel Award, Society of Molecular Imaging, 2008

    Graduate Professional Travel Award, Wayne State University, 2005

    Young Investigator Travel Award, Society of Molecular Imaging, 2005

    Conferred Distinction for Masters studies, Andhra University, India, 1996

    Tipirneni Lakshmi Perumal Educational Trust Merit Scholarship, Andhra University, India, 1994-1995

    Conferred Distinction for Baccalaureate studies, Andhra Loyola College, India, 1994

    Tipirneni Lakshmi Perumal Educational Trust Merit Scholarship, Andhra Loyola College, India, 1993-1994

  • Videos & Media +
  • Events +
  • Contact & Locations +

    Department/Division

    • Radiology and Radiological Science - Neuroradiology
    • Oncology
    • Medicine - Clinical Pharmacology

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