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Fan Pan, M.D., Ph.D.

Photo of Dr. Fan Pan, M.D., Ph.D.

Assistant Professor of Oncology

Research Interests: Oncology; Immunotherapy Strategies to Combat Cancer

Background

Titles

  • Assistant Professor of Oncology

Departments / Divisions

Education

Degrees

  • M.D., Shanxi Medical College - Taiyuan - Shanxi (242-39 before 1971) (China) (1993)
  • Ph.D., Chinese Acadamy of Preventive Medicine - Beijing (China) (1996)

Research & Publications

Selected Publications

Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Nature. 2007 Jan 25;445(7126):433-6. Epub 2007 Jan 17. PMID: 17230191.

Pan F, Yu H, Dang EV, Barbi J, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in regulatory T cells. Science. 2009 Aug 28;325(5944):1142-6. doi: 10.1126/science.1176077. Epub 2009 Aug 20. PMCID: PMC2859703.

Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Topalian SL, Semenza GL, Dang CV, Pardoll DM and Pan F. Control of Th17/Treg Balance by Hypoxia-inducible Factor 1. Cell. 2011 Sep 2;146(5):772-84. doi: 10.1016/j.cell.2011.07.033. Epub 2011 Aug 25. PMCID: PMC3387678.

Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM. Pan F* and Li B*. (Co-corresponding authors) The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. PMID: 23973223.

Huang-Yu Yang, Joseph Barbi, Cao-Yi Wu, Ying Zheng, Paolo D.A.Vignali, Jin-Hui Tao, Benjamin V. Park, Xingmei Wu, Xuhao Ni, Drew M. Pardoll, Huabin Li, Pan F. The microRNA MiR-17 modulates Foxp3+ Regulatory T cell activity by targeting Foxp3 collaborating factors. Immunity. 2016.

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