Skip Navigation
Find a Doctor
 
 
 
 

 

Photo of Dr. Seyed Ali Fatemi, MD

Ali Fatemi, MD

Seyed Ali Fatemi, MD
Assistant Professor of Neurology
Male
Main Location

The Johns Hopkins Hospital

View All Locations

Titles

  • Assistant Professor of Neurology
  • Assistant Professor of Pediatrics

Expertise

Neurology

Research Interests

The brain''s white matter consists of axons that build up a complex network of connections between different neurons. Axons are wrapped by oligodendrocytes, cells that produce myelin, a thick membrane that isolates and protects the axons. Other cellsastrocytesare important constituents of white matter, supporting brain metabolism and acting as gatekeepers for nutrients that enter the brain. Disorders of white matter can affect axons, oligodendrocytes or astroyctes. Perinatally acquired white matter injury is the leading cause of cerebral palsy and other neuropsychiatric conditions in children born prematurely. Dr. Fatemi is a member of the neuroscience laboratory and the F.M. Kirby Research Center for functional brain imaging. He collaborates closely with a multi-disciplinary group of scientists at the Hugo W. Moser Research Institute and at Johns Hopkins to study the molecular mechanism involved in white matter development and injury in cerebral palsy and perinatal white matter injury, using molecular, histological and advanced MRI techniques to examine rodent models. The neuroscience laboratory also uses animal models as a test bed for cell-based therapeutic approaches, including stem cells and progenitor cells derived from mouse embryos. Dr. Fatemi and his colleagues evaluate the survival of transplanted cells in injured animals, and how they migrate to the desired site and eventually restore white matter function, either by differentiation into more mature cells or by providing support to the injured tissue. Dr. Fatemi is also a member of the Neurogenetics Research Center at Kennedy Krieger and is involved in clinical and imaging research studies of patients with X-linked adrenoleukodystrophy.

Biography

 

During this initial period, Dr. Fatemi collaborated with a team of scientists and developed new imaging methods in patients with leukodystrophies (rare genetic diseases that affect the brain''s white matter) and coordinated an internet-2 based imaging network for these diseases. He then left Kennedy Krieger Institute to train in general pediatrics and then completed a child neurology residency at the Massachusetts General Hospital, an affiliate of Harvard Medical School. Dr. Fatemi returned to the Kennedy Krieger Institute in 2008 as faculty.

 

He is a member of the Child Neurology Society, the International Child Neurology Association, the Society for Neuroscience, the American Academy of Neurology and the International Society for Magnetic Resonance in Medicine. He has served as ad hoc reviewer for the Journals Child Development and American Journal of Neuroradiology.

 

Languages

  • English
  • Arabic
  • Farsi
  • German
Additional Resources +

Is This You? Edit Profile

 
 
 
 

© The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System. All rights reserved.