Dr. Bivalacqua maintains an active research portfolio in order to improve the care of cancer patients. A major focus of his research lab is to develop novel molecular-based targeted therapies for bladder cancer and preservation of erectile function in prostate cancer patients undergoing radical prostatectomy using novel agents.
Dr. Bivalacqua's basic, translational and clinical research is funded by peer-reviewed awards and he has recently been acknowledged for his accomplishments in research with several grants including a Career Development Award from the National Institute of Health (NIH), the Patrick C. Walsh Prostate Cancer Research Fund, and the American Urological Association (AUA) "Rising Star” Award. He serves as principal investigator for clinical trials in both prostate and bladder cancer including the only tissue engineered bladder cancer clinical trial in this country.
Improving Sensitivity of Urine Cytology for Bladder Cancer
Incontinent Urinary Diversion Using an Autologous Neo-Urinary Conduit
Erythropoietin to Enhance Erection Recovery in Men Following Radical Prostatectomy (EPO)
Intravesical Administration of INSTILADRIN (rAd-IFN With Syn3) in Patients With Bladder Cancer
Sundi D, Wang VM, Pierorazio PM, Han M, Bivalacqua TJ, Ball MW, Antonarakis ES, Partin AW, Schaeffer EM, Ross AE. "Very-high-risk localized prostate cancer: definition and outcomes." Prostate Cancer Prostatic Dis. 2013 Nov 5. doi: 10.1038/pcan.2013.46.
Chalfin HJ, Gurda GT, Hammers HJ, Netto GJ, Bivalacqua TJ. "Renal cell carcinoma presenting with brain metastasis from a 1.6 cm primary tumor." Can J Urol. 2013 Oct;20(5):6965-7.
Sundi D, Wang V, Pierorazio PM, Han M, Partin AW, Tran PT, Ross AE, Bivalacqua TJ. "Identification of men with the highest risk of early disease recurrence after radical prostatectomy." Prostate. 2014 Jan 22. doi: 10.1002/pros.22780.
Musicki B, Bivalacqua TJ, Champion HC, Burnett AL. "Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis." J Sex Med. 2014 Feb;11(2):424-30. doi: 10.1111/jsm.12391.
Kates M, Gorin MA, Deibert CM, Pierorazio PM, Schoenberg MP, McKiernan JM, Bivalacqua TJ. "In-hospital death and hospital-acquired complications among patients undergoing partial cystectomy for bladder cancer in the United States." Urol Oncol. 2014 Jan;32(1):53.e9-53.e14. doi: 10.1016/j.urolonc.2013.08.024.