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Trinity Jude Bivalacqua, M.D., Ph.D.

Associate Professor of Urology


Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Associate Professor of Urology
  • Associate Professor of Oncology
  • Associate Professor of Surgery

Centers & Institutes



The Johns Hopkins Hospital

Appointment Phone: 410-955-6070

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-6070

601 N. Caroline Street
Baltimore, MD 21287 map


Bladder Cancer, Genitourinary Sarcoma, Penile Cancer, Prostate Cancer, Robotic Prostatectomy, Urology


Dr. Trinity J. Bivalacqua is an assistant professor of urology, oncology and surgery at the Johns Hopkins School of Medicine. His areas of clinical expertise include surgical treatment of genitourinary sarcomas, prostate, bladder and penile cancer.

Dr. Bivalacuqa graduated from Tulane University with undergraduate, graduate and medical degrees. He joined the faculty after completing his general surgery and urology training at The Johns Hopkins Hospital. He also completed an American Urological Association (AUA) Foundation Fellowship.

Dr. Bivalacqua’s main areas of expertise include radical surgical procedures for sarcomas and invasive bladder cancer and reconstructive surgery of the urinary tract following radical cystectomy or pelvic exenteration. He has expertise in open, endoscopic, laparoscopic and robotic surgery, and he offers individualized treatment options for patients with a wide range of genitourinary malignancies. His other areas of focus include surgical management of erectile dysfunction (inflatable penile prosthesis) and treatment of benign prostatic hyperplasia (Green Light Laser Prostatectomy and open simple prostatectomy).

His laboratory currently investigates novel molecular pathways that are involved in post-radical prostatectomy erectile dysfunction and identification of novel biomarkers for the early diagnosis and staging of bladder cancer.

Dr. Bivalacqua has received national and international recognition for his research involving the outcome of surgery for pelvic malignancies and the pathophysiology and novel treatment strategies for erectile dysfunction. He has recently been acknowledged for his accomplishments in research with several grants including a Career Development Award from the National Institute of Health (NIH), the Patrick C. Walsh Prostate Cancer Research Fund and the American Urological Association “Rising Star” Award. more

Featured Video

Prostate Cancer Recovery- Dr.Bivalacqua

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    Additional Information

  • Education +


    • Tulane University School of Medicine / MD PhD (2004)


    • Johns Hopkins University School of Medicine / Urology (2009)


    • American Board of Urology / Urology (2012)
  • Research & Publications +

    Research Summary

    Dr. Bivalacqua maintains an active research portfolio in order to improve the care of cancer patients. A major focus of his research lab is to develop novel molecular-based targeted therapies for bladder cancer and preservation of erectile function in prostate cancer patients undergoing radical prostatectomy using novel agents.

    Dr. Bivalacqua's basic, translational and clinical research is funded by peer-reviewed awards and he has recently been acknowledged for his accomplishments in research with several grants including a Career Development Award from the National Institute of Health (NIH), the Patrick C. Walsh Prostate Cancer Research Fund, and the American Urological Association (AUA) "Rising Star” Award. He serves as principal investigator for clinical trials in both prostate and bladder cancer including the only tissue engineered bladder cancer clinical trial in this country.

    Clinical Trials:

    Improving Sensitivity of Urine Cytology for Bladder Cancer

    Incontinent Urinary Diversion Using an Autologous Neo-Urinary Conduit

    Erythropoietin to Enhance Erection Recovery in Men Following Radical Prostatectomy (EPO)

    Intravesical Administration of INSTILADRIN (rAd-IFN With Syn3) in Patients With Bladder Cancer

    Selected Publications View all on PubMed

    1. Sundi D, Wang V, Pierorazio PM, Han M, Partin AW, Tran PT, Ross AE, Bivalacqua TJ. "Identification of men with the highest risk of early disease recurrence after radical prostatectomy." Prostate. 2014 Jan 22. doi: 10.1002/pros.22780.
    2. Musicki B, Bivalacqua TJ, Champion HC, Burnett AL. "Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis." J Sex Med. 2014 Feb;11(2):424-30. doi: 10.1111/jsm.12391.
    3. Kates M, Gorin MA, Deibert CM, Pierorazio PM, Schoenberg MP, McKiernan JM, Bivalacqua TJ. "In-hospital death and hospital-acquired complications among patients undergoing partial cystectomy for bladder cancer in the United States." Urol Oncol. 2014 Jan;32(1):53.e9-53.e14. doi: 10.1016/j.urolonc.2013.08.024.
    4. Sundi D, Wang VM, Pierorazio PM, Han M, Bivalacqua TJ, Ball MW, Antonarakis ES, Partin AW, Schaeffer EM, Ross AE. "Very-high-risk localized prostate cancer: definition and outcomes." Prostate Cancer Prostatic Dis. 2013 Nov 5. doi: 10.1038/pcan.2013.46.
    5. Chalfin HJ, Gurda GT, Hammers HJ, Netto GJ, Bivalacqua TJ. "Renal cell carcinoma presenting with brain metastasis from a 1.6 cm primary tumor." Can J Urol. 2013 Oct;20(5):6965-7.
  • Academic Affiliations & Courses +
  • Activities & Honors +


    • Thomas S.K. Change Trainee Award, American Society of Andrology, 1999
    • 1st Prize Essay Contest, Society for the Study of Impotence, 2000
    • 3rd Prize Montague Boyd Essay Contest, Southeastern Section AUA, 2001
    • Basic Research Award in Integrated Biology, Tulane Health Research Day, 2001
    • Jorgen U. Schlegel Award for Excellence in Research, Tulane School of Medicine, 2001
    • Jean François Ginestíe Prize: Best Paper on Basic Science of Sexual Medicine, 2002
    • Best Basic Science Abstract: Sexual Medicine Society of North America, 2003
    • Arnold M Seligman Award for Most Outstanding Surgical Resident, Sinai Hospital of Baltimore, 2004
    • John T. Halsey Award, Tulane School of Medicine, 2004
    • Joseph Hume Memorial Award, Tulane School of Medicine, 2004
    • Outstanding Surgical Intern, Johns Hopkins University, 2004
    • Student Recognition Award, American Federation for Medical Research , 2004
    • Yamanouchi Best Abstract Prize: Impotence, AUA, 2004
    • Best Basic Science Abstract, 2005
    • Zorgniotti-Newman Prize (Co-author): Best Clinical Research in Sexual Medicine, 2006
    • 1st Prize Resident Essay Contest: Laboratory Science, Mid-Atlantic Section AUA, 2007
    • Alpha Omega Alpha, Johns Hopkins University, 2007
    • Astellas USA Foundation MD/PhD Fellowship, American Urological Association Foundation , 2007 - 2008
    • Best Basic Science Abstract, 2007
    • 2nd Prize Resident Essay Contest: Laboratory Science, America Urological Association, 2008
    • Cook Urology Travel Award, American Society of Andrology, 2008
    • Jack Lapides Neurourology Essay Contest Grand Prize Winner, 2008
    • Outstanding Graduate, AUA Foundation, 2008
    • Trainee Award, American Society of Andrology, 2008
    • Young Investigator Award , AUA Research Forum, 2008
    • Young Investigator Award , Society of Basic Urologic Research (SBUR), 2010
    • Best Poster, American Urological Association (AUA) Annual Meeting, 2011
    • Foundation Rising Star in Urology Research Award, American Urological Association (AUA) , 2012


    • Alpha Omega Alpha (AOA)
    • American Society of Andrology
    • American Urologic Association (AUA)
    • Endourological Society
    • International Society of Sexual Medicine
    • Sexual Medicine Society of North America, Inc.
    • Society for Basic Urologic Research (SBUR)
    • Society of Urologic Oncology (SUO)
  • Videos & Media +


    Trinity J. Bivalacqua, M.D, Ph.D, Johns Hopkins Medicine, Urology

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