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Karen E. Seymour, M.A., Ph.D.

Photo of Dr. Karen E. Seymour, M.A., Ph.D.

Assistant Professor of Psychiatry and Behavioral Sciences

Expertise: Attention Deficit Hyperactivity Disorder, Clinical Psychology, Mood Disorders, Neuropsychiatry

Research Interests: Attention-Deficit/Hyperactivity Disorder; emotion regulation; irritability; frustration and/or frustrative non-reward; neuroimaging; ADHD and mood disorders (unipolar depression; bipolar disorder) comorbidity; affective neuroscience ...read more

Locations

Kennedy Krieger Institute Outpatient Center
Appointment Phone: 443-923-9400

716 North Broadway
Room 335
Baltimore, MD 21205 map
Phone: 443-923-9247

Background

As a licensed clinical psychologist and researcher, I have over 15 years of experience treating and conducting research with families of children with psychopathology, particularly attention-deficit/hyperactivity disorder (ADHD). 

As a clinician, I am focused on diagnostic clarification of child psychopathology especially for complex cases. I use research-grade assessment measures including diagnostic interviews, parent, youth and teacher rating scales, and specialty clinician administered scales as needed to complete comprehensive diagnostic evaluations. To schedule an appointment, please call the Kennedy Krieger Institute intake line at: 443-923-9400 and request a diagnostic evaluation with Dr. Seymour (Outpatient Psychiatry)

As a researcher, my work has focused on elucidating the biobehavioral mechanisms underlying emotion regulation (ER) deficits such as emotional face processing affective processing bias and frustration tolerance  in children with ADHD using affective neuroscience techniques including: computerized behavioral tasks to probe ER, collection of physiological data related to ER, and multimodal neuroimaging. I have extensive training in the use of computerized behavioral tasks to probe ER including data collection, processing and analysis. In collaboration with Stewart Mostofsky, MD and his Center for Neurodevelopmental and Imaging Research (CNIR) at Kennedy Krieger Institute, I have designed and am piloting a novel behavioral frustration task in children with ADHD. Further, as supported by an NIMH Career Development Award (K23) designed to examine biobehavioral correlates of frustration in children with ADHD, I am integrating structural and functional neuroimaging methods into my research under the mentorship of Dr. Mostofsky. For more information about Dr. Seymour's ongoing research projects please visit:  http://www.hopkinsmedicine.org/psychiatry/research/volunteers.html or contact LNIR@kennedykrieger.org.

...read more

Titles

  • Assistant Professor of Psychiatry and Behavioral Sciences

Education

Degrees

  • B.A., University of Notre Dame (Indiana) (2001)
  • M.A., University of Maryland (College Park) (Maryland) (2006)
  • Ph.D., University of Maryland (College Park) (Maryland) (2010)

Additional Training

Alpert Warren School of Medicine, Brown University, Providence, Rhode Island, 2011, NIH T32 Postdoctoral Fellowship in Child Mental Health; Children''s National Medical Center, Washington, DC, 2009, Child Clinical Psychology Pre-doctoral Internship

Research & Publications

Research Summary

As a licensed clinical psychologist and researcher, I have over 15 years of experience treating and conducting research with families of children with psychopathology, particularly attention-deficit/hyperactivity disorder (ADHD). Throughout the years, my research has focused on three main areas. Prior to attending graduate school, I conducted research examining the biological basis of ADHD in relation to the DAT1 gene and the effect of DAT1 genotype on stimulant medication response in children with ADHD (Stein et al., 2003; Stein et al., 2005). During graduate school, I examined the effects of parental psychopathology (e.g., ADHD, depression) on treatment outcomes in children with ADHD (Chronis-Tuscano, Seymour et al., 2008; Chronis-Tuscano, Rooney, Seymour, et al., 2010; Chronis-Tuscano et al; 2011, 2013). Finally, my independent research has focused on examining emotion regulation (ER) deficits in children with ADHD and other forms of psychopathology (Seymour et al, 2012, Seymour, Chronis-Tuscano et al., 2013; Seymour, Reinblatt et al., 2015). As an Assistant Professor at Johns Hopkins University School of Medicine, my work has focused on elucidating the biobehavioral mechanisms underlying ER deficits such as emotional face processing (Seymour, Pescosolido, et al., 2013; Seymour, Jones et al. 2016), affective processing bias (Seymour, Kim et al., 2015), and frustration tolerance (Seymour et al., under review) in children with ADHD using affective neuroscience techniques including: computerized behavioral tasks to probe ER, collection of physiological data related to ER, and multimodal neuroimaging. I have extensive training in the use of computerized behavioral tasks to probe ER including data collection, processing and analysis. In collaboration with Stewart Mostofsky, MD and his Center for Neurodevelopmental and Imaging Research (CNIR) at Kennedy Krieger Institute, I have designed and am piloting a novel behavioral frustration task in children with ADHD. Further, as supported by an NIMH Career Development Award (K23) designed to examine biobehavioral correlates of frustration in children with ADHD, I am integrating structural and functional neuroimaging methods into my research under the mentorship of Dr. Mostofsky. 

Clinical Trial Keywords

Attention-Deficit/Hyperactivity Disorder, ADHD, Emotion, Emotion Regulation, Frustration

Selected Publications

View all on Pubmed

Seymour, K.E., Macatee, R., & Chronis-Tuscano, A.M. (in press). Frustration Tolerance in Children with ADHD. Journal of Attention Disorders

Seymour, K.E., Jones, R.N., Cushman, G.K., Galvan, T., Puzia, M.E., Kim, K.L., Spirito, A., & Dickstein, D.P. (2016). Emotional face identification in adolescent suicide attempters and adolescents engaged in non-suicidal self-injury. European Journal of Child and Adolescent Psychiatry, 25(3), 247-59. PMID: 26048103.

Seymour, K.E., Mostofsky, S.M., & Rosch, K.S. (2016). Cognitive Load Differentially Impacts Response Control in Girls and Boys with ADHD. Journal of Abnormal Child Psychology, 44(1), 141-54. PMCID: PMC4517984.

Barry, T. D., Sturner, R. A., Seymour, K., Howard, B. H., McGoron, L., Bergmann, P., Kent, R., Sullivan, C., Tomeny, T. S., Pierce, J. S., Coln, K. L., Goodlad, J. K., & Werle, N. (2015). School-based screening to identify children at risk for attention-deficit/hyperactivity disorder: Barriers and implications. Children's Health Care. DOI: 10.1080/02739615.2014.948160

Seymour, K.E., Kim, K.L., Cushman, G.K., Puzia, M., Weissman, A., Galvan, T., & Dickstein, D.P. (2015). Affective processing bias in youth with primary bipolar disorder or primary attention-deficit hyperactivity disorder. European Journal of Child and Adolescent Psychiatry, 24(11), 1349-59. PMID: 25724546.

Activities & Honors

Honors

  • Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD), 2013
  • Young Scientist Research Fund Award recipient
  • Pediatric Extramural Loan Repayment Program Grant, National Institues of Mental Health, 2012 - 2014
  • Honors Distinction, University of Maryland, 2007
  • Pediatric Loan Repayment Program Grant, National Institutes of Mental Health, 2016

Memberships

  • American Psychological Association (APA)
  • APA, Division 53 Society for Clinical Child and Adolescent Psychology
  • Association for Behavioral and Cognitive Therapies (ABCT)
  • Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD)
  • Organization of Human Brain Mapping (OHBM)
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