Hand Reconstruction, Hand Surgery, Hand Transplant, Plastic Surgery, Upper Extremity Surgery
Investigating tolerance strategies for composite tissue allografting; Enhancing nerve regeneration to improve functional outcome of composite tissue allotransplantation
W. P. Andrew Lee, M.D. is the Milton T. Edgerton, MD, Professor and Chairman of Department of Plastic and Reconstructive Surgery at the Johns Hopkins University School of Medicine. A hand surgeon and scientific researcher, he conducts investigation on tolerance strategy for vascularized composite allografts, such as hand or face transplants, to ameliorate the need for long-term systemic immunosuppression.
Dr. Lee established multi-disciplinary programs for hand transplantation at Johns Hopkins and University of Pittsburgh using an immunomodulatory protocol based upon investigations in his laboratory. He led the surgical team that performed the first bilateral hand transplant (2009) and the first above-elbow transplant (2010) in the U.S. A salient feature of the protocol is single-agent immunosuppression (monotherapy) that minimizes the long-term risks of hand transplantation.
Dr. Lee has served as the Chair of the American Board of Plastic Surgery (2012-13) and the President of the American Society for Surgery of the Hand (2011-12). In 2008 he helped to found the American Society for Reconstructive Transplantation, for which he currently serves as the President-Elect. He was elected the Chairman of Plastic Surgery Research Council in 2002 and President of the Robert H. Ivy Society of Plastic Surgeons in 2010-11. Dr. Lee has received more than 70 awards and honors, including the Kappa Delta Award from the American Academy of Orthopaedic Surgeons, and Sumner Koch Award and Sterling Bunnell Traveling Fellowship from the American Society for Surgery of the Hand. In 2014 he is recognized by the American Association of Plastic Surgeons with the Research Achievement Award for basic research.
Dr. Lee has mentored approximately 80 pre-doctoral and post-doctoral researchers in over two decades, and has authored more than 165 original publications in peer-reviewed journal and 40 textbook chapters on hand surgery and composite tissue transplant subjects. The book co-edited by him, Transplantation of Composite Tissue Allografts, was published in 2008. He has been an invited speaker or visiting professor in more than 40 institutions around the world, and served on the editorial boards of Transplantation and Journal
of Surgical Research. In 2014 he co-founded the journal Vascularized Composite Allotransplantation, and serves as its co-Editor-in-Chief.
An honors graduate in physics from Harvard College, Dr. Lee received his medical degree from Johns Hopkins University School of Medicine, where he also completed his general surgery residency and microvascular research fellowship. He completed his plastic surgery fellowship at the Massachusetts General Hospital and his orthopedic hand fellowship at the Indiana Hand Center. In 1993 he joined the plastic surgery faculty at Massachusetts General Hospital, Harvard Medical School, and became the director of the Plastic Surgery Research Laboratory and subsequently chief of hand service in Department of Surgery. In 2002 Dr. Lee was appointed as the Division Chief of Plastic Surgery at the University of Pittsburgh. He was recruited to Johns Hopkins in 2010 to be the inaugural chairman of its newly established Department of Plastic and Reconstructive Surgery.