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Photo of Dr. Shaoyong Yu

Shaoyong Yu, M.D.

Assistant Professor
Assistant Professor of Medicine
Male

Titles

  • Assistant Professor
  • Assistant Professor of Medicine

Centers & Institutes

  • Conte Digestive Diseases Basic and Translational Research Core Center
  • Digestive Disease and Motility Center
  • Neurogastroenterology, Center for

Technology Expertise

GI Physiology, Neurobiology, and Mucosal Immunology

Biography

Dr. Shaoyong Yu is Assistant Professor of Medicine in the Gastroenterology and Hepatology division. He studies neurogastroenterology and motility.

Dr. Yu received medical and master’s degrees from Tongji Medical University, and a master of public health degree from the Johns Hopkins Bloomberg School of Public Health before joining the Johns Hopkins faculty.

Languages

  • English
Additional Resources +
  • Education +

    Education

    • MPH, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD
    • MD/MS, Tongii Medical University, P.R. China

    Training

    • Johns Hopkins University School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, MD, Research Fellow
    • Johns Hopkins University School of Medicine, Division of Gastroenterology and Hepatology, Baltimore, MD, Research Fellow
  • Research & Publications +

    Research Summary

    Dr. Yu's research has been focused on neuro-immune interactions in the GI tract. Specifically, he is interested in studying the cellular and molecular mechanisms underlying the pathogenesis of visceral hypersensitivity and development of functional GI disorders.

    Selected Publications

    1. Yu S.,  Undem  BJ,  Kollarik  M. Vagal  afferent  nerves  with  nociceptive  properties  in guinea-pig  oesophagus. J Physiol.  2005;563(Pt  3):831-42.
    2. Yu S, Kollarik M, Ouyang A, Myers AC, Undem BJ. Mast cell-mediated long-lasting increases in excitability of vagal C fibers in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2007;293(4):G850-6.
    3. Yu S, Ru F, Ouyang A, Kollarik M. The Effect of 5-Hydroxytryptamine on Esophageal Vagal Afferent Nerve C-fiber and A?-fiber Subtypes in Guinea Pig.Neurogastroenterol Motil. 2008;20(9):1042-50.
    4. Yu S, Stahl E, Li Q, Ouyang A. Antigen inhalation induces mast cells and eosinophils infiltration in the guinea pig esophageal epithelium involving histamine-mediated pathway. Life Sci. 2008;82:324-330.
    5. Yu S, Ouyang A. TRPA1 in bradykinin-induced mechanical hypersensitivity of vagal C fibers in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2009; 296(2):G255-65.
    6. Yu S, Li Q, Cavanaugh S, Undem BJ, Ouyang A. Characterization of mast cell subtypes, distribution, and antigen-induced activation in the guinea pig esophagus. Dis Esophagus. 2009;22(7):600-5.
    7. Yu S, Gao GF, Peterson BZ, Ouyang A. TRPA1 in Mast Cell Activation-induced Long-lasting Mechanical Hypersensitivity of Vagal Afferent C fibers in Guinea Pig Esophagus. Am J Physiology Gastrointestinal & Liver. 2009;297(1):G34-42.
    8. Yu S. Ouyang A. Effect of Cationic Protein on Mechano-excitability of Vagal Afferent Nerve Subtypes in Guinea Pig Esophagus. Am J Physiology Gastrointestinal & Liver Physiol. 2011; 301:G1052-G1058. 
    9. Gao GF, Ouyang A, Kaufman MP, Yu S. ERK1/2 Signaling Pathway in Mast Cell Activation-induced Sensitization of Esophageal Nodose C-fiber Neurons.Dis Esophagus 2011;24:194-203.
    10.  Zhang S, Grabauskas G, Wu X, Joo MK, Heldsinger A, Song I, Owyang C, Yu S. Role of Prostaglandin D2 in Mast Cell Activation-induced Sensitization of Esophageal Vagal Afferents. Am J Physiology Gastrointestinal & Liver Physiol 2013; 305: G908-16.
  • Academic Affiliations & Courses +
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  • Events +
  • Contact & Locations +

    Department/Division

    • Medicine - Gastroenterology

    For Research Inquiries Contact

    Phone: 410-502-2455

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