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Michael Anthony Jacobs, Ph.D.

Photo of Dr. Michael Anthony Jacobs, Ph.D.

Director, Imaging Radiological Assessment Team (IRAT), Sidney Kimmel Comprehensive Cancer Center

Associate Professor of Radiology and Radiological Science

Expertise: Breast Imaging, Magnetic Resonance Imaging, New Imaging Modalities, Radiology

Research Interests: Image analysis MRI/MRSI; Breast cancer imaging; New analysis tools for MRI and other imaging; Novel multiparametric MRI and PET/CT assessment; High Intensity Focused Ultrasound; Prostate Imaging ...read more

Contact for Research Inquiries

712 Rutland Ave.
Traylor Building, Room 309
Baltimore, MD 21205 map

Background

Dr. Michael A. Jacobs is an Associate Professor in the Johns Hopkins Medicine Department of Radiology and Radiological Science. His research focuses on developing radiological methods for detecting, monitoring, and treating breast cancer, with a particular focus on transferring research from the lab to the clinic.  He is Board Certified in Diagnostic Medical Physics by the American Board of Radiology.

Dr. Jacobs received his undergraduate degree in mathematics and engineering science from the University of Michigan-Flint. He earned his Ph.D. in biomedical physics from Oakland University. He completed his fellowship in radiology at the Johns Hopkins University School of Medicine. Dr. Jacobs joined the Johns Hopkins faculty in 2003.

He serves on the National Board of the American College of Radiology Imaging Network (ACRIN) Breast Imaging committee, as a member of the subcommittee of molecular and functional imaging of the ACRIN and as co-director of the Imaging Radiological Assessment Team (IRAT) of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. He is also one of the principal investigators on the Quantitative Imaging Network (QIN) U01 at Johns Hopkins University for developing novel methods for determining treatment response in clinical trials.

His work has been recognized with numerous awards and honors, including the 2012 Distinguished Investigator Awards from the Academy of Radiology Research, three Certificate of Merit Awards at the Radiological Society of North America, a bronze medal from the American Roentgen Ray Society and a National Research Service Awards Cancer Research Training Grant. He also was awarded three patents for his work related to radiological imaging.

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Titles

  • Director, Imaging Radiological Assessment Team (IRAT), Sidney Kimmel Comprehensive Cancer Center
  • Associate Professor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • B.S., University of Michigan (Michigan) (1993)
  • Ph.D., Oakland University (Michigan) (1999)

Additional Training

  • Diagnostic Medical Physics, American Board of Radiology (2016)
Departments of Neurology and Radiology, Henry Ford Hospital, Detroit, MI, 2000, Stroke Research Coordinator; Depts. of Neurology and Radiology. Henry Ford Hospital, Detroit, MI, 1999, Senior Research Assistant; Mathematics Dept. Oakland University, Detroit, MI, 1995, Graduate Research Assistant; United States Air Force: Non Commissioned Officer (NCO), Wilford Hall Medical Center (Level 1 Trauma Center), San Antonio, TX, 1992, Asst. NCOIC Supervisor of Emergency Room Medical Technicians; The Johns Hopkins University School of Medicine, Baltimore, MD, 2002, Radiological Fellow

Research & Publications

Research Summary

Dr. Jacobs is involved in breast, prostate and metastatic cancer imaging research. His research examines new analysis tools for magnetic resonance imaging (MRI) and PET/CT and is particularly focused on multiparametric MRI/PET/CT assessment and image analysis of radiological imaging. He holds a number of patents related to using and manipulating radiological images.

Technology Expertise Keywords

Diffusion; ADC; computer science; cancer; PET; CT; Radiomics

Clinical Trial Keywords

PET/CT, Whole Body Imaging, Dynamic Contrast Imaging, Diffusion Imaging, Magnetic Resonace Imaging

Clinical Trials

Pre-Operative Radiation and Veliparib for Breast Cancer

Pulsed Radiofrequency vs. Steroid Injections for Occipital Neuralgia

Selected Publications

View all on Pubmed

Jacobs MA, Barker, PB, Bluemke DA, Herskovits EH, Bhujwalla Z. Benign and malignant breast lesions: diagnosis with multiparametric MR imaging. Radiology. 2003;229(1):225-232

Ei Khouli RH, Jacobs MA, Mezban SD, Huang P, Kamel IR, Macura KJ, Bluemke DA. Diffusion-weighted imaging improves the diagnostic accuracy of conventional 3.0-T breast MR imaging. Radiology. 2010; 256(1):64-73

Leung DG, Carrino JA, Wagner KR, Jacobs MA. Whole-body MRI evaluation of facioscapulohumeral muscular dystrophy. Muscle and Nerve. 2015; epub: Jan 16

Jacobs MA, Wolff AC, Macura KJ, Stearns V, Ouwerkerk R, El Khouli RH, Bluemke DA, Wahl R. Multiparametric and multimodality functional radiological imaging for breast cancer diagnosis and early treatment response assessment. Journal of the National Cancer Institute. Monographs 2015;51:40-46

Parekh V, Jacobs MA. Radiomics: a new application from established techniques. Expert Review of Precision Medicine and Drug Development. 2016;1(2):207-226

Activities & Honors

Honors

  • Distinguished Investigator Award, Academy of Radiology Research, 2012
  • Bronze medal winner at the American Roentgen Ray Society, Washington DC, 2008
  • Two Certificates of Merit Awards, Radiological Society of North America, 2010
  • Certificate of Merit Award, Radiological Society of North America, 2009
  • National Research Service Award Cancer Research Training Grant, 2002
  • First Place Award in Clinical Research, JHMI Oncology Center Research Day, 2000

Memberships

  • American Association of Physicists in Medicine
  • American College of Radiology Imaging Network (ACRIN), By Invitation Only
  • Imaging Response Assessment Team (IRAT) Network

Professional Activities

  • American Association of Physicists in Medicine
  • American College of Radiology Imaging Network (ACRIN)
    By Invitation Only
  • Imaging Response Assessment Team (IRAT) Network
  • Chair DWI MRI Imaging. NCI – Quantitative Cancer Imaging, NCI, 2014
  • Chair/Co-chair DCE MRI Imaging. NCI – Quantitative Cancer Imaging March 5-6, NCI, 2011 - 2014
  • Co-Director, Department of Radiology and Oncology, 2005 - 2014
    IRAT committee
  • Co-Director, JHU ICMIC Imaging, Department of Radiology, 2007
    Image and Statistical Analysis
  • Co-PI, JHU Quantitative Cancer Imaging Program, 2011
  • Director, Department of Radiology and Oncology, 2014
    IRAT committee
  • Reviewer, California Breast Cancer Research Board UCLA, 2004 - 2007
  • Reviewer, Susan B. Komen Foundation for breast cancer, Dallas, 2004 - 2006
  • Reviewer, NIH/NCI, 2005 - 2010
    P01-Targeted Therapy Panel
  • Reviewer, University of Maryland, 2005
    Internal Grants
  • Reviewer, R01-NIH/NCI, 2011
    Drug Discovery and Therapy Panel
  • Reviewer, DOD for Prostate, 2012
  • Reviewer, UK Wellcome Burroughs, UK
  • Reviewer, Novitis European Grant Foundation, England
  • Reviewer, French National Evaluation Committee for Cancer translational research
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