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Photo of Dr. Hyunseok Kang

Hyunseok Kang, M.D., M.P.H.

Assistant Professor of Oncology

Male  | Languages: English, Japanese, Korean

Appointment Phone

410-955-8893

Main Location

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Assistant Professor of Oncology

Centers & Institutes

Departments

Locations

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Appointment Phone: 410-955-8893

401 N. Broadway
Baltimore, MD 21231 map
Phone: 410-502-0678
Fax: 410-955-8587

Expertise

Head and Neck Cancers, Medical Oncology, Salivary Gland Tumors, Squameous Cell Carcinoma, Thyroid Cancer

Biography

A clinician-scientist with a focus on novel therapeutics in head and neck cancer, Hyu (Hyunseok) is a member of the Upper Aerodigestive Cancer Program.

Hyu's long-term goal is to develop a translational and clinical investigation program focused on head and neck cancer, including squamous cell carcinomas and salivary gland cancers. In addition, he serves as an attending on the inpatient solid tumor service, establish a continuity outpatient clinic, and supervise Hematology and Oncology fellows in clinic.

...read more

    Additional Information

  • Education +

    Degrees

    • Yonsei University College of Medicine / MD (2002)

    Residencies

    • Mount Sinai St. Luke's - Roosevelt Hospitals / Internal Medicine (2010)

    Fellowships

    • Emory University School of Medicine (2013)

    Certifications

    • American Board of Internal Medicine / Internal Medicine (2010)
    • American Board of Internal Medicine / Medical Oncology (2013, 2016)
  • Research & Publications +

    Research Summary

    Dr. Kang is interested in developing novel therapeutics in treatment of head and neck squamous cell carcinomas and salivary gland cancers. Dr.Kang's goal is to provide better way to understand and manage head and neck cancers through the research.

    Clinical Trial Keywords: Head and Neck Cancer, Salivary Gland Cancer, Immunotherapy, Drug Development

    Selected Publications

    Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Retting EM, Guo T, Pickering CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, Gourin CG, Ha PK, Kang H, Kiess A, Koch WM, Myers JN, Quon H, Richmon JD, Sidransky D, Tufano RP, Westra WH, Bettegowda C, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Agrawal N. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Sci Transl Med 2014;7(293):294ra104

    Chung CH, Guthrie VB, Masica DL, Tokheim C, Kang H, Richmon J, Agrawal N, Fakhry C, Quon H, Subramaniam RM, Zuo Z, Seiwert T, Chalmers ZR, Frampton GM, Ali SM, Yelensky R, Stephens PJ, Miller VA, Karchin R, and Bishop JA. Genetic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. Ann Oncol. 2015;26(6):1216-23

    Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Retting EM, Guo T, Pickering CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, Gourin CG, Ha PK, Kang H, Kiess A, Koch WM, Myers JN, Quon H, Richmon JD, Sidransky D, Tufano RP, Westra WH, Bettegowda C, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Agrawal N. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Sci Transl Med 2014;7(293):294ra104

    Chung CH, Guthrie VB, Masica DL, Tokheim C, Kang H, Richmon J, Agrawal N, Fakhry C, Quon H, Subramaniam RM, Zuo Z, Seiwert T, Chalmers ZR, Frampton GM, Ali SM, Yelensky R, Stephens PJ, Miller VA, Karchin R, and Bishop JA. Genetic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing. Ann Oncol. 2015;26(6):1216-23

    Kang H, Kiess AP and Chung CH. Emerging biomarkers in head and neck cancer in the era of genomics. Nat Rev Clin Oncol 2015;12(1):11-26.

    Chung CH, Lee JW, Slebos RJ, Howard JD, Perez J, Kang H, Fertig EJ, Considine M, Gilbert J, Murphy BA, Nallur S, Paranjape T, Jordan RC, Garcia J, Burtness B, Forastiere AA, and Weidhaas JB. A 3'UTR KRAS variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma. Ann Oncol. 2014;25(11):2230-6

    Kang H, Gillespie T, Goodman M, Brodie SA, Brandes M, Ribeiro M, Khuri FR, Ramalingam SS, Shin DM, Brandes JC. Long-term use of valproic acid in United States Veterans is associated with reduced risk of smoking related head and neck cancers. Cancer 2014;120(9):1394-1400

    Brodie SA, Li G, El-Kommos A, Kang H, Ramalingam SS, Behera M, Gandhi K, Kowalski J, Sica GL, Khuri FR, Vertino PM, Brandes JC. Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer. Cancer Prev Res (Phila). 2014;7(3):351-61

    Kang H, Kauh JS. Chemotherapy in the treatment of metastatic gastric cancer: Is there a global standard? Curr Treat Options Oncol 2011;12(1):96-106

    Kang H, Rha SY, Oh KW, Nam CM. Greentea consumption and stomach cancer risk: A meta-analysis. Epidemiology Health 2010; 32:e2010001

    Ahn EM, Song JI, Kang H, Park JJ, Yoo SH, Huh BR. The Symptom Expression and the Illness Behavior of North Korean Defectors: Toward an Effective Therapeutic Relationships. J Korean Acad Fam Med 2007; 28(5): 352-358

    Donato NJ, Perez M, Kang H, Siddik ZH, Ling YH, Perez-Soler R. EGF Receptor and p21waf1 Expression are Reciprocally Altered as ME-180 Cervical Carcinoma Cells Progress from High to Low Cisplatin Sensitivity. Clin Cancer Res 2000;6(1):193-202

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Memberships

    • American Association for Cancer Research, 2011

      Member

    • American College of Physicians, 2015

      Fellow (FACP)

    • American Society of Clinical Oncology
      Member
    • American Society of Hematology
      Member

    Professional Activities

    • Co-director for Oncology Grand Rounds, Educational committee, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 2015
  • Videos & Media +
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