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Marilyn S. Albert, Ph.D.

Photo of Dr. Marilyn S. Albert, Ph.D.

Director of Cognitive Neuroscience, Department of Neurology

Professor of Neurology

Contact for Research Inquiries

The Johns Hopkins Hospital
Department of Neurology
1620 McElderry Street
Baltimore, MD 21287 map
Phone: 410-614-3040
Fax: 410-502-2189

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Background

Dr. Marilyn Albert received her PhD degree in Physiological Psychology from McGill University in Montreal and completed a fellowship in Neuropsychology at Boston University School of Medicine. She served on the faculty of the Harvard Medical School for over 22 years.

Now a Professor of Neurology at Johns Hopkins and Director of the Division of Cognitive Neuroscience, Dr. Albert focuses on the cognitive and brain changes associated with aging and Alzheimer’s disease (AD). Her work has delineated the cognitive changes associated with aging and early AD, along with potential methods of early identification of AD. She has also identified lifestyle factors that promote maintenance of mental abilities with advancing age.

Dr. Albert’s research currently focuses on the early identification of AD, and potential ways of monitoring the progression of disease to permit early intervention.

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Titles

  • Director of Cognitive Neuroscience, Department of Neurology
  • Professor of Neurology
  • Professor of Neuroscience
  • Professor of Pathology
  • Professor of Psychiatry and Behavioral Sciences

Research & Publications

Research Summary

  • Major research interests are in the area of cognitive change with age
  • Disease-related changes of cognition (with a particular focus on Alzheimer's Disease)
  • The relationship of cognitive change to brain structure and function, as assessed through imaging (e.g., MRI, fMRI, SPECT) and genetics
  • Recent studies have focused on how to predict who will develop Alzheimer's disease over time
  • Additional research efforts have included epidemiological studies of predictors of the maintenance of cognitive function, as well as cognitive decline

Clinical Trials

Alzheimer’s Disease Neuroimaging Initiative

Selected Publications

View all on Pubmed

  1. Soldan A, Pettigrew C, Li S, Wang MC, Moghekar A, Selnes OA, Albert M, O'Brien R, BIOCARD Research Team. Relationship of cognitive reserve and cerebrospinal fluid biomarkers to the emergence of clinical symptoms in preclinical Alzheimer's disease. Neurobiol Aging. 2013; 34: 2827-2834.
  2. Bakker A, Kraus G, Albert M, Speck C, Jones L, Stark C, Yassa M, Bassett S, Shelton A, Gallagher M. Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron 2012; 74: 467-474.
  3. Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011; 7: 270-279.
  4. Dickerson B, Stoub T, Shah R, Sperling R, Killiany R, Albert M, Hyman B, Blacker D, Detoledo-Morrell L. Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults. Neurol 2011; 76: 1395-1402.
  5. Yassa M, Stark C, Bakker A, Albert M, Gallagher M, Stark C. High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment. Neuroimage 2010; 51: 1242-1252.
  6. Blacker D, Lee H, Muzikansky A, Martin E, Tanzi R, McArdle J, Moss M, Albert M. Neuropsychological measures in normal individuals that predict subsequent cognitive decline. Arch Neurol, 2007; 64: 862-871.

Videos & Media

Lectures and Presentations

  • Age-Related Cognitive Decline
    https://www.alz.washington.edu/NONMEMBER/SPR10/Albert.pdf
  • Challenges for the Early Diagnosis of Alzheimer’s Disease
    2012 Reynolds Visiting Professorship Lecture (10/31/2014)
    UAMS
  • New Frontiers in Dementia: 
    https://www.youtube.com/watch?v=QFoj3HZVGYc/ (10/01/2010)
  • Healthy Cognitive Aging and Transitions to Neuropathology: I
    Center for Vital Longevity/U.T. Dallas-ACC Program 2013

Recent News Articles and Media Coverage

Changing the Future of Aging, Doorways to Discovery (November 2014)

An Alzheimer's Early Warning? NeuroLogic (Summer 2014)

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