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Marian Kollarik, M.D., Ph.D.

Photo of Dr. Marian Kollarik, M.D., Ph.D.

Associate Professor of Medicine

Research Interests: Modulation of visceral sensory nerves by inflammation; Regulation of cough reflex

Background

Dr. Marian Kollarik is an associate professor of medicine at the Johns Hopkins University School of Medicine. 

Dr. Kollarik received his M.D. and Ph.D. from Comenius University – Jessenius Faculty of Medicine in the Slovak Republic. 

His research interests include the modulation of visceral sensory nerves by inflammation and the regulation of cough reflex.

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Titles

  • Associate Professor of Medicine

Centers & Institutes

Education

Degrees

  • M.D., Comenius University - Jessenius Faculty of Medicine (Slovak Republic) (1997)
  • Ph.D., Comenius University - Jessenius Faculty of Medicine (Slovak Republic) (2004)

Research & Publications

Lab

Sensory nerves gather information about the tissue. Our research focuses on specific phenotype of visceral sensory nerves, termed nociceptive, that detect stimuli associated with impeding or actual tissue damage. Nociceptors trigger defensive reflexes and/or sensations of discomfort and pain. For example, nociceptors initiate cough, sneezing, nasal itching, bronchoconstriction and mucus hypersecretion in the respiratory system, and pain and hypersecretion in the gastrointestinal system. An increase in nociceptive activity contributes significantly to the pathogenesis of respiratory and gastrointestinal diseases and their symptoms. Importantly, inflammation profoundly alters properties of nociceptive nerves per se, leading in general to exaggerated nociceptive responsiveness. Our studies center on this aspect of visceral nociception in allergic and non-allergic inflammation. We carry out electrophysiological and anatomical studies in isolated tissues and reflex studies in animal models.

Videos & Media

Lectures and Presentations

  • Esophageal sensory nerves and eosinophilic esophagitis
    2014-2015 Clinical Immunology Wednesday Research Conferences , Baltimore, MD (03/18/2015)
    Johns Hopkins
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