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Christine Anne Pratilas, M.D.
Assistant Professor of Oncology and Pediatrics
Assistant Professor of Oncology
Expertise: Bone Cancer, Bone Tumors, Chemotherapy, Clinical Trials, Ewing's Sarcoma, Medical Oncology, Melanoma, Osteosarcoma, Pediatric Cancer, Pediatric Oncology, Rhabdomyosarcoma, Sarcoma, Sarcoma and Musculoskeletal Tumors , Soft Tissue Sarcoma, Soft Tissue Tumors ...read more
Research Interests: oncogenes; BRAF mutations; cancer cell signaling pathways; molecularly targeted therapy; RAF and MEK inhibitor therapy; pediatric sarcomas; pediatric phase I clinical trials ...read more
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The Johns Hopkins Hospital (Main Entrance)
Appointment Phone: 410-955-8751
1800 Orleans St.
The Charlotte R. Bloomberg Children's Center Building, 11th Floor
Baltimore, MD 21287 map
Dr. Christine Pratilas is a hematologist and medical oncologist at the Sidney Kimmel Comprehensive Cancer Center and an Assistant Professor of Oncology and Pediatrics at the Johns Hopkins University School of Medicine. She joined the Hopkins our pediatric sarcoma/solid tumor team in 2014.
Dr. Pratilas received her undergraduate degree in Biology from Drew University in New Jersey and her medical degree from the Robert Wood Johnson Medical School, where she completed her internship and residency between 1999 and 2002. From 2002 to 2005 she was a fellow in hematology and oncology in the Memorial Sloan Kettering Cancer Center (MSKCC) Department of Pediatrics, and in the Department of Pediatric Hematology and Oncology at New York Weill Cornell Medical Center. She then worked for three years as a postdoctoral research fellow in Dr. Neal Rosen’s Molecular Oncogenesis Laboratory at MSKCC.
From 2006 to 2014 she attended on the Pediatric Oncology unit at MSKCC, supervising the care of children while overseeing the work of fellows, residents, and nurse practitioners. In 2011 she began her specialization in the care of pediatric sarcoma patients, overseeing their care in a weekly clinic.
During her years in the lab of Dr. Rosen, a distinguished molecular geneticist, Dr. Pratilas focused her research on signal transduction, which involves figuring out how a cell’s internal molecular pathways work, and how those pathways can be molecularly controlled. This knowledge is the basis for developing promising new molecularly targeted cancer therapies, which is the focus of Dr. Pratilas’s research. One of her most important contributions to date has been to advance our understanding of how certain proteins that can be mutated in cancer known as RAF inhibitors affect a cancer cell’s behavior.
Here at Johns Hopkins, Dr. Pratilas will continue her work on signal transduction pathways, concentrating on pediatric sarcomas, in order to develop novel therapeutics for children with these tumors.
- Assistant Professor of Oncology and Pediatrics
- Assistant Professor of Oncology
Centers & Institutes
- MD; Pediatrics, Rutgers - Robert Wood Johnson Medical School (1999)
- Robert Wood Johnson University Hospital / Pediatrics (2002)
- Memorial Sloan-Kettering Cancer Center / Hematology and Oncology (2005)
- American Board of Pediatrics / Pediatric Hematology (2006, 2014)
- American Board of Pediatrics / Pediatrics - General (2002, 2010)
- 2002 American Board of Pediatrics (renewed 2012)
- 2006 American Board of Pediatrics Hematology/Oncology Subspecialty
- 2014 Maryland Medical license
- 2015 (exp.) DEA
- New York Medical License (2002)
Research & Publications
10/12/10 Awarded, Biomarkers for Cancer Treatment - U.S. Patent No. 7,812,143 B2; Inventors: Pratilas, C; Rosen, N
Patent # U.S. Patent No. 7,812,143 B2 | 10/12/2010
Activities & Honors
- 2011 Young Investigator Award, Melanoma Research Alliance
- 2004 Foundation Young Investigators Award, ASCO
- 2004 Scholar-in-Training Award (95th Annual Meeting), AACR
- 2004 Doris Duke Award, MSKCC
- 1997 Medical Society Scholarship, Morris County, NJ
- 1995 Magna cum laude, Phi Beta Kappa, Drew University
- 1992 – 1995 Merit Scholarship, Drew University
- 1992 – 1995 Edward Bloustein Garden State Scholarship, New Jersey