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Marie-France Penet, Ph.D.

Photo of Dr. Marie-France Penet, Ph.D.

Assistant Professor of Radiology and Radiological Science

Research Interests: Applying magnetic resonance imaging and magnetic resonance spectroscopy to study the tumor microenvironment; Early detection of ovarian cancer; cancer cachexia; theranostic imaging ...read more

Background

Dr. Marie-France Penet is an Assistant Professor in the Johns Hopkins Medicine Department of Radiology and Radiological Science and a member of the Johns Hopkins Kimmel Cancer Center. Her research focuses on magnetic resonance imaging.

Dr. Penet received her undergraduate degree and master’s degree in cellular biology and physiology from the University of Aix-Marseille II in France. She also earned her Ph.D. in biology from the University of Aix-Marseille II. Dr. Penet completed a post-doctorate fellowship in radiology at the Johns Hopkins University School of Medicine in 2010. Dr. Penet joined the Johns Hopkins faculty in 2011.

Dr. Penet received the 2012 Tina Brozman Foundation grant to study ovarian cancer with imaging.

...read more

Titles

  • Assistant Professor of Radiology and Radiological Science
  • Assistant Professor of Oncology

Departments / Divisions

Education

Degrees

  • B.Sc., University d'Aix-Marseille II - Faculte de Medicine - Marseille - (France) (2000)
  • Ph.D., University d'Aix-Marseille II - Faculte de Medicine - Marseille - (France) (2005)

Additional Training

University of Aix-Marseille II, France, Marseille, France, 2002, Post Graduate Immunology; The JHU ICMIC Program of the Russell H. Morgan Department of Radiology and Radiological Science, the Johns Hopkins University School of Medicine, Baltimore, MD, 2010, Postdoctoral Fellow

Research & Publications

Research Summary

Dr. Penet has a strong background in imaging mice with MR techniques. Her imaging expertise began during her Ph.D. when she performed brain imaging studies of mice infected with Plasmodium berghei ANKA, parasites that induce the murine form of cerebral malaria. As a post-doctoral fellow in Pr. Zaver Bhujwalla’s laboratory, she worked on imaging orthotopic prostate cancer models. She has also performed surgical orthotopic implantation of prostate tumor pieces in male SCID mice.

Selected Publications

Penet MF, Abou-Hamdan M, Coltel N, Cornille E, Grau GE, de Reggi M, Gharib B. "Protection against cerebral malaria by the low molecular-weight thiol panthetine" PNAS 105:1321-1326 (2008) (PMCID: PMC2234136).

Penet MF, Pathak AP, Raman V, Ballesteros P, Artemov D, Bhujwalla ZM. "Noninvasive Multi-parametric Imaging of Metastasis-Permissive Microenvironments in a Human Prostate Cancer Xenograft" Cancer Res 69:8822-9 (2009) (PMCID: PMC2783669).

Penet MF, Gadiya MM, Krishnamachary B, Nimmagadda S, Pomper MG, Artemov D, Bhujwalla ZM. Metabolic signatures imaged in cancer-induced cachexia. Cancer Res. 71: 6948-56, (2011). PMCID:PMC3217079

Chen Z*, Penet MF*, Nimmagadda S, Li C, Banerjee SR, Winnard PT Jr, Artemov D, Glunde K, Pomper MG, Bhujwalla ZM. PSMA-Targeted Theranostic Nanoplex for Prostate Cancer Therapy. ACS Nano. 6: 7752-62, (2012). PMCID:PMC4066818.

Penet MF, Shah T, Bharti S, Krishnamachary B, Artemov D, Mironchik Y, Wildes F, Maitra A, Bhujwalla ZM. Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism. Clin Cancer Res. 21: 386-95, (2015). PMCID:PMC4297549

Activities & Honors

Honors

  • Travel Award, ISMRM, 2009
  • Travel Award, ISMRM, 2007
  • Grant to study ovarian cancer with imaging, Tina Brozman Foundation, 2012

Memberships

  • American Association of Cancer Research, 2006
  • International Society of Magnetic Resonance in Medicine, 2006
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