Holdhoff trained as a clinical translational investigator for the last three years under Stuart Grossman, M.D., Luis Diaz, M.D., and Bert Vogelstein, M.D. He will continue his translational brain tumor research in the Kimmel Cancer Centers Brain Cancer program and the Ludwig Center for Cancer Genetics and Therapeutics. Holdhoffs primary focus will be the development of blood-based tumor markers for patients with malignant gliomas and primary CNS lymphomas and novel translational clinical trials.
Holdhoff received his medical degree in 2003 from Freie Universitt Berlin. He received his doctorate degree (Ph. D.) from Charit University Medicine Berlin magna cum laude. He completed his internal medicine training at Johns Hopkins Bayview Medical Center and he became board-certified in internal medicine in 2007. Holdhoff completed his medical oncology and neuro-oncology training at Johns Hopkins at the end of June 2010 and has already received ABIM board certification in Medical Oncology. He was given the 2010 ASCO Young Investigator Award for his proposal on the development of a blood-based biomarker for malignant gliomas.
Holdhoffs position will actively link the Brain Cancer program and the Ludwig Center, thereby promoting a translational research exchange between the two groups.