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Kimberly L. Ostrow, M.A., Ph.D.

Photo of Dr. Kimberly L. Ostrow, M.A., Ph.D.

Assistant Professor of Neurology

Background

Dr. Kimberly L. Ostrow is an assistant professor in the Department of Neurology at Johns Hopkins University School of Medicine. She is currently engaged in the study the genetics and epigenetics of neurofibromatosis, schwannomatosis, and other basic science aspects of peripheral nerve tumor biology. She is also the co-director of the International Schwannomatosis Database. This project, funded by the Children’s Tumor Foundation, brings together experts in the field of schwannomatosis to enroll patients in the database and promote collaborative research.

Dr. Ostrow earned a BS in biochemistry at SUNY Geneseo in Geneseo, New York. She completed an MA and PhD in biochemistry, from the SUNY Buffalo/Roswell Park Cancer Institute Graduate Division.  Dr. Ostrow post-doctoral associate in the Department of Biophysics at SUNY/Buffalo School of Medicine before joining Johns Hopkins in 2005. At Johns Hopkins she completed a post-doctoral fellowship in molecular genetics in the Department of Otolaryngology, Head and Neck Cancer Research Division, in the Laboratory of David Sidransky M.D.

Dr. Ostrow is a member of the Society for Neuroscience, Children’s Tumor Foundation and American Neurological Association. Her work has been recognized with the New Investigator Award from the American Heart Association.

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Titles

  • Assistant Professor of Neurology

Departments / Divisions

Education

Degrees

  • B.S., State University of New York (Geneseo) (New York) (1995)
  • M.A., State University of New York (Buffalo) (New York) (1999)
  • Ph.D., State University of New York (Buffalo) (New York) (2002)

Research & Publications

Research Summary

Dr. Ostrow has established collaborations with clinicians and basic scientists in the Johns Hopkins Departments of Neurology, Neurosurgery, and Oncology - affiliated with the Comprehensive Neurofibromatosis Center in order to study the genetics and epigenetics of neurofibromatosis, schwannomatosis, and other basic science aspects of peripheral nerve tumor biology. She is  the Co-Director of the International Schwannomatosis Database. This project funded by the Children’s Tumor Foundation brings together experts in the field of schwannomatosis to enroll patients in the database and promote collaborative research. 

Selected Publications

View all on Pubmed

Ostrow KL, Hoque MO, Loyo M, Brait M, Greenberg A , Siegfried J, Grandis JR, Gaither Davis A, Bigbee WL, Rom W, and Sidransky D. (2010). Molecular Analysis of Plasma DNA for the Early Detection of Lung Cancer by Quantitative Methylation Specific PCR, Clinical Cancer Research, 16 (13): 3463-72.

Ostrow KL, Guerrero-Preston R, Hoque M, Greenberg A, Rom W, Sidransky D, (2013) Cigarette Smoke Induces Methylation of the Tumor Suppressor Gene NISCH, Epigenetics 8(4): 383-8.

Ostrow, KL K Donaldson, J Blakeley, A Belzberg, A Hoke (2014) Pain related genes in schwannomas. Annals of Neurology 76, S71

Ostrow, KL, K Donaldson, J Blakeley, A Belzberg, A Hoke (2015) Immortalized Human Schwann Cell Lines Derived From Tumors of Schwannomatosis Patients. PLos ONE 10(12) e0144620. doi:10.1371/journal.pone.0144620

Ostrow KL, Bergner AL, Blakeley J, Evans G, Ferner R, Friedman, JM, Harris G, Korf B, Langmead S, Leschziner G, Mautner V, Merker V, Papi L, Plotkin S, Slopis JM, Smith M, Stemmer-Rachamimov A, Yohay K, Belzberg AJ (2016) Creation of an International Registry to Support Discovery in Schwannomatosis American Journal of Medical Genetics doi: 10.1002/ajmg.a.38024. [Epub ahead of print]

Activities & Honors

Honors

  • New Investigator Award, American Heart Association, 2004 - 2005

Memberships

  • American Cancer Society- Certified Breast Cancer Awareness Community Outreach Speaker, 2010 - 2011
  • Member of the International Schwannomatosis Database Collaborators, 2012 - 2016
  • Society for Neuroscience, 2012
  • Children’s Tumor Foundation, 2012
  • American Neurological Association, 2014
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