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Irina Burd, M.D., Ph.D.

Photo of Dr. Irina Burd, M.D., Ph.D.

Director, Integrated Research Center for Fetal Medicine

Associate Professor of Gynecology and Obstetrics

Female

Languages: English, Russian

Expertise: Fetal Cardiology, Gynecology and Obstetrics, High Risk OB, Multiple Gestations, Obstetrics, Pregnancy, Childbirth, Women's Reproductive Health ...read more

Research Interests: fetal brain development

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Locations

Johns Hopkins Outpatient Center
Appointment Phone: 410-955-6700

601 N. Caroline St.
Baltimore, MD 21287 map

The Johns Hopkins Hospital
Appointment Phone: 410-955-6700

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

Background

Dr. Irina Burd is an associate professor in the Johns Hopkins Medicine Department of Gynecology and Obstetrics. She holds a joint appointment in the Department of Neurology, where she also serves as associate professor. Her areas of clinical expertise include high-risk pregnancy conditions and fetal brain development. Dr. Burd was recruited to Johns Hopkins Medicine to spearhead the development of the field of fetal neurology. She is the founder and director of the Integrated Research Center for Fetal Medicine at the Johns Hopkins University School of Medicine.

Dr. Burd earned her undergraduate degree from Rutgers University and completed the M.D./Ph.D. program at the University of Medicine and Dentistry of New Jersey, now Robert Wood Johnson Medical School. She completed her residency in obstetrics and gynecology at Thomas Jefferson University Hospital and performed a fellowship in maternal-fetal medicine at the University of Pennsylvania. Dr. Burd joined the Johns Hopkins faculty in 2011.

Dr. Burd is a member of the Society for Maternal-Fetal Medicine, the Society for Gynecologic Investigation and the Perinatal Research Society. She has published numerous peer-reviewed research articles and is the recipient of numerous honors, including the Ikaria Research Award from the Perinatal Research Society, a research award from the American Board of Obstetrics and Gynecology/American Association of Obstetricians and Gynecologists Foundation, the Thomas R. Boggs Jr. Research Award from the Philadelphia Perinatal Society, and the Passano Foundation Clinician Scientist Award. Dr. Burd is a recipient of a National Institutes of Health award to study the role of IL1β receptor in perinatal brain injury.

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Titles

  • Director, Integrated Research Center for Fetal Medicine
  • Director of Research, Division of Maternal Fetal Medicine
  • Associate Professor of Gynecology and Obstetrics
  • Associate Professor of Neurology

Education

Degrees

  • MD, Rutgers - Robert Wood Johnson Medical School (2003)

Board Certifications

  • American Board of Obstetrics and Gynecology / Maternal and Fetal Medicine (2013)
  • American Board of Obstetrics and Gynecology / OB/GYN-General (2010)

Research & Publications

Research Summary

Dr. Burd developed a research program studying the pathogenesis of fetal brain injury with exposure to intrauterine inflammation. She studies prenatally used neuroprotective agents that could be used in utero to prevent cerebral palsy and a spectrum of neurobehavioral outcomes.

Selected Publications

View all on Pubmed

Johnson CT, Farzin A, Burd I. Current management and long-term outcomes following chorioamnionitis. Obst Gynecol Clin N Amer. 2014 (In Press) doi.org/10.1016/j.ogc.2014.08.007

Rosenzweig JM, Lei J, Burd I. Interleukin-1 receptor blockade in perinatal brain injury. Frontiers in Pediatrics. 2014 (In Press).

Lei J,* Nigrini E,* McKinney S, Tarabulsi G, Borbiev T, Burd I. Neuronal nitric oxide synthase in cord blood as a biomarker of long-term sequelae of neonatal encephalopathy. FASEB (submitted) *-equally contributed

Lei J,* Firdaus W,* Fatemi A, AlRebh S, Johnston MV, Burd I. Maternal immunomodulatory therapy with mesenchymal stem cells for prematurity-associated perinatal brain injury. Am J Obstet Gynecol (submitted) *-equally contributed

Graham E, Adami R, McKinney S, Anderson C, Burd I, Witter F. Diagnostic accuracy of fetal heart rate monitoring in the identification of neonatal encephalopathy. Obstet Gynecol. 2014 Sep;124(3):507-13. doi: 10.1097/AOG.0000000000000424.

Andrikopoulou M, Almalki A, Farzin A, Cordeiro CN, Johnston MV, Burd I. Perinatal biomarkers of prematurity: Early identification of neurologic injury. Int J Dev Neurosci. 2014 Aug;36:25-31. doi: 10.1016/j.ijdevneu.2014.04.002.

Adler D, Simon E, Lei J, Dada T, Borbiev T, Johnston MV, Kadam S, Burd I. Circadian cycle dependent EEG biomarkers of pathogenicity in adult mice following prenatal exposure to in utero inflammation. Neuroscience. 2014 Sep 5;275:305-13. doi: 10.1016/j.neuroscience.2014.06.022.

Carver AR, Andrikopoulou M, Lei J, Tamayo E, Gamble P, Hou Z, Zhang J, Mori S, Saade GR, Costantine MM, Burd I. Maternal pravastatin prevents altered fetal brain development in a preeclamptic CD-1 mouse model. PLoS One. 2014 Jun 25;9(6):e100873. doi: 10.1371/journal.pone.0100873.

Leitner K, Al Shammary M, McLane M, Johnston M, Elovitz M, Burd I. IL-1 receptor blockade prevents fetal cortical brain injury but not preterm birth in a mouse model of inflammation-induced preterm birth and perinatal brain injury. Am J Reprod Immunol. 2014 May;71(5):418-26. doi: 10.1111/aji.12216.

Mainigi M, Olalere D, Burd I, Sapienza C, Bartolomei M, Coutifaris C. Elucidating mechanisms of abnormal placentation and fetal growth. Biol Repro 2013 Dec 18. [Epub ahead of print]

Burd I, Zhang F, Dada T, Mishra M, Borbiev T, Lesniak W, Baghlaf B, Kannan S, Kannan R. Fetal uptake of intraamniotically delivered dendrimers in a mouse model of intrauterine inflammation and preterm birth. Nanomedicine. 2014 Aug;10(6):1343-51. doi: 10.1016/j.nano.2014.03.008.

Dada T, Rosenzweig J, Shammary M, Firdaus, W, Al Rebh S, Borbiev T, Tekes A, Zhang J, Alqahtani E, Mori S, Pletnikov M, Johnston MV, Burd I. Mouse model of intrauterine inflammation: Sex-specific differences in long-term neurologic and immune sequelae. Brain Behav Immun. 2014 May;38:142-50. doi: 10.1016/j.bbi.2014.01.014.

Burd I, Balakrishnan B, Kannan S. Models of fetal brain injury, intrauterine inflammation, and preterm birth. Am J Reprod Immunol. 2012 Apr;67(4):287-94.
Werner EF, Wheeler S, Burd I. Creating decision trees to assess cost-effectiveness in clinical research. J Biostatistics and Biometrics 2012 doi:10.4172/2155-6180.S7-004.

Activities & Honors

Honors

  • Super Doctors Rising Star, Maryland, Virginia and Washington DC area, Washington Post, 2013
  • Passano Foundation Clinician Scientist Award, 2012
  • Johns Hopkins University Clinician Scientist Award, 2012
  • Pfizer SGI President’s Award, Society for Gynecologic Investigation, 2011
  • Thomas Boggs Award (Philadelphia Perinatal Society), 2010
  • Ikaria Early Career Investigator Award (The Perinatal Research Society), 2010
  • NIH Loan Repayment Award, 2009 - 2011
  • American Board of Obstetrics and Gynecology/American Association of Obstetricians and Gynecologists Foundation (ABOG/AAOGF) Scholar, 2009 - 2012
  • Howard Lees Kent Memorial Prize for Outstanding Scholarship, Thomas Jefferson University, 2007
  • Research Award, Thomas Jefferson University, 2007
  • S. Leon Israel Award for Excellence in Research (Obstetrical Society of Philadelphia), 2006
  • Administrative Chief, Department of Obstetrics and Gynecology, 2006
  • Berlex Best Teaching Resident Award, 2005
  • Arnold P. Gold Foundation Resident Award for Humanism in Medicine and Excellence in Teaching, 2005
  • American College of Surgeons Certificate of Appreciation for Exemplary Teaching, 2005
  • Jefferson Ob-Gyn Excellence in Teaching Awards, 2003 - 2005
  • UMDNJ Academic Excellence in Obstetrics and Gynecology Award, 2003
  • President, Gold Humanism in Medicine Honor Society, 2002
  • UMDNJ- RWJMS Research Achievement Award, 2002
  • Honorable Mention Manuscript, Residency Competition, 2002
  • Merck/AFAR Scholarship in Pharmacology of Aging, 1998

Videos & Media

Innovation, Education, Collaboration

Recent News Articles and Media Coverage

  • Study Links Zika Virus to Joint Problems in Babies, USA Today (08/2016)
  • Update on the Spread of the Zika Virus in the U.S., The Diane Rehm Show (08/2016)
  • Health Experts Stressing Preparedness as Zika Outbreak Hits U.S., ABC News (08/2016)
  • CDC: Zika Passed from Woman to Man via Sex, The Center for Infectious Disease Research and Policy (07/2016)
  • Pregnant Mums Who Catch Flu Could be Putting their Unborn Child at Risk, The Daily Express (U.K.) (06/2016)
  • Drop in Birth Defects Slowed After Folic Acid Fortification, Reuters (05/2016)
  • Kate Middleton Suffering from Hyperemesis Gravidarum. What Does It Mean? Yahoo Health (10/2014)
  • Pregnant Women's Immune Response May Be Linked to Autism in Babies, UPI (02/2014)

 

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