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Photo of Dr. Robert G. Hamilton, PhD

Robert G. Hamilton, PhD

Professor
Professor of Medicine
Male

Titles

  • Professor
  • Director, Johns Hopkins Dermatology, Allergy and Clinical Immunology (DACI) Reference Laboratory
  • Senior Laboratory Investigator
  • Professor of Medicine
  • Professor of Pathology

Research Interests

Humoral (antibody) immune responses in allergic and infectious disease; Natural rubber latex allergy; Diagnostic allergy testing; Medical product and environmental allergen testing

Biography

Dr. Robert Hamilton is a Professor of Medicine in the division of Allergy and Clinical Immunology. He studies humoral (antibody) immune responses in allergic and infectious disease, natural rubber latex allergy, diagnostic allergy testing and medical product and environmental allergen testing.

Dr. Hamilton holds bachelor's and master's degrees from the University of Michigan and a PhD in radiological sciences and immunology from Johns Hopkins University. He completed fellowships at the VA Medical Center in Bronx, N.Y., and at the Brookhaven National Laboratory in Long Island, N.Y., before joining the Johns Hopkins faculty in 1990. His work has been recognized with a Mallinckrodt Scholarship Award from the American Society of Nuclear Medicine in 1979 and a Berson-Yalow Award from the American Society of Nuclear Medicine in 1980.

Languages

  • English
Additional Resources +
  • Education +

    Education

    • Ph.D., Johns Hopkins University, Baltimore, MD, 1980
    • M.S., University of Michigan, Ann Arbor, MI, 1973
    • B.S., University of Michigan, Ann Arbro, MI, 1972

    Fellowships

    • Brookhaven National Laboratory, Long Island, NY, 1974
    • VA Medical Center, Bronx, NY, 1981
  • Research & Publications +

    Research Summary

    My current research interests focus on (1) the role of IgE and IgG antibodies in modulating human allergic disease, (2) the utility of these antibody measurements in the diagnosis and management of human allergic disease, and (3) the immunogenicity of new and FDA-approved drugs and vaccines. In 1967, IgE antibody was identified as the "gate-keeper" of allergic reactions. By binding onto mast cells and basophils, it controls the release of mediators that follow allergen exposures. Our work focuses on the accurate quantification of allergen-specific IgE, IgG and IgA in an attempt to identify indicators of risk for and protection from allergic reactions. Together with my colleague N. Franklin Adkinson Jr., M.D., we are investigating the safety of new and approved drugs for their ability to elicit IgE and IgG antibody responses as part of clinical trials leading to FDA approval. Finally, I oversee the Johns Hopkins Dermatology, Allergy and Clinical Immunology (DACI) Reference Laboratory which is a full service diagnostic allergy laboratory that provides IgE and IgG antibody measurements as well as measurements of mast cell tryptase, eosinophil cationic protein, cotinine, indoor aeroallergens and endotoxin that aid in the diagnosis and management of human allergic disease.

    Lab

    Johns Hopkins Dermatology, Allergy and Clinical Immunology Reference Laboratory

  • Academic Affiliations & Courses +

    Graduate Program Affiliation

    Biomedical Engineering Program
  • Activities & Honors +

    Honors

    Robert Hamilton Awarded Mallinckrodt Scholarship Award, American Society of Nuclear Medicine, 1979

    Robert HamiltonAwarded Berson-Yalow Award, American Society of Nuclear Medicine, 1980
  • Videos & Media +
  • Upcoming Events +
  • Contact & Locations +

    Department/Division

    • Pathology
    • Medicine - Allergy and Clinical Immunology

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