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Anthony Louis DeFulio, Ph.D.

Assistant Professor of Psychiatry and Behavioral Sciences

See Research on Pubmed



  • Assistant Professor of Psychiatry and Behavioral Sciences

Centers & Institutes

  • Learning and Health, Center for

Research Interests

Drug abstinence; Naltrexone Pharmacotherapy; Contingency management; Experimental Analysis of behavior; Incentive-based intervention; Medication adherence; Substance abuse treatment


  • English

Additional Resources

Additional Resources +
  • Education +


    • B.S., University of Florida, Gainesville, Florida, 1996
    • M.S., University of North Texas, Denton, Texas, 2002
    • Ph.D., University of Florida, Gainesville, Florida, 2007


    • Johns Hopkins University, Baltimore, Maryland, 2009, Behavioral Pharmacology Research Unit
  • Research & Publications +

    Research Summary

    My main professional interests are in substance abuse treatment, medication adherence, incentive-based intervention, and the experimental analysis of behavior. My work can be broadly classified as contingency management. The primary focus of my research is to create sustainable long-term interventions for promoting healthy behaviors in low-income populations.

    My recent completed projects show that employment-based abstinence reinforcement is an effective long term maintenance intervention in refractory methadone patients, and that employment-based reinforcement can promote adherence to naltrexone pharmacotherapy in heroin dependent adults living in poverty.

    Current NIH-funded projects include a smartphone-based antiretroviral adherence intervention, further investigation of employment-based contingencies and naltrexone pharmacotherapy, the development of a pre-trial diversion program that features employment-based abstinence reinforcement, and the development of a wage subsidy program designed to simultaneously increase community employment while reinforcing drug abstinence in methadone patients.

    Selected Publications View all on PubMed

    DeFulio A, Donlin WD, Wong CJ, Silverman K. Employment-Based Abstinence Reinforcement as a Maintenance Intervention for the Treatment of Cocaine Dependence: A Randomized Controlled Trial. Addiction. 2009;104(9):1530-1538.

    DeFulio A, Iati C, Needham M, Silverman K.  Modification of perseverative responding that increased earnings but impeded skill acquisition in a job skills training program.  J Appl Behav Anal. 2009;42(3):627-640.

    DeFulio A, Silverman K. Employment-based abstinence reinforcement as a maintenance intervention for the treatment of cocaine dependence: post-intervention outcomes. Addiction. 2011;106(5):960-967.

    Everly JJ, DeFulio A, Koffarnus MN, Leoutsakos JM, Donlin W, Aklin WM, Umbricht A, Fingerhood M, Bigelow GE, Silverman K. Employment-based reinforcement of adherence to depot naltrexone in unemployed opioid-dependent adults: A randomized controlled trial. Addiction. 2011; 106(7):1309-1318.

    DeFulio A, Everly JJ, Leoutsakos JS, Umbricht A, Fingerhood M, Bigelow GE, Silverman K. Employment-based reinforcement of adherence to an FDA approved extended release formulation of naltrexone in opioid-dependent adults: A randomized controlled trial. Drug Alcohol Depend. 2012; 120(1-3):48-54.

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  • Contact & Locations +


    • Psychiatry and Behavioral Sciences - Behavioral Biology

    For Research Inquiries Contact

    Johns Hopkins Bayview Medical Center
    Center for Learning and Health
    5200 Eastern Avenue, Ste. W142
    Baltimore MD, 21224

    Office Phone: 410-550-9935
    Fax: 410-550-7495


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