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R. Scott Stephens, M.D.

Robert Scott Stephens, M.D.
Director, Oncology and Bone Marrow Transplant Critical Care
Assistant Professor of Medicine


Appointment Phone


Main Location

The Johns Hopkins Hospital

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »


  • Director, Oncology and Bone Marrow Transplant Critical Care
  • Assistant Professor of Medicine



The Johns Hopkins Hospital

Appointment Phone: 410-955-3467

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-550-0545

Johns Hopkins Bayview Medical Center

5501 Hopkins Bayview Circle
Asthma and Allergy Center
Baltimore, MD 21224 map
Phone: 410-550-0545
Fax: 410-550-2612


Acute Respiratory Distress Syndrome, Cardiac Disease in the Critically Ill Patient, Critical Care Medicine , Pulmonary Disease and Critical Care Medicine, Pulmonary Diseases, Pulmonary Medicine, Septic Shock

Research Interests

Acute Respiratory Distress Syndrome; Pulmonary Endothelial Barrier Function; Extracorporeal Membrane Oxygenation; Pulmonary Endothelial Antioxidant Regulation; Acute Respiratory Failure; Critical Care Education

    Additional Information

  • Education +


    • University of Pennsylvania School of Medicine / MD (2003)


    • Johns Hopkins University School of Medicine / Medicine (2006)


    • Johns Hopkins University School of Medicine / Pulmonary Medicine (2010)


    • American Board of Internal Medicine / Critical Care Medicine (2011)
    • American Board of Internal Medicine / Internal Medicine (2006)
    • American Board of Internal Medicine / Pulmonary Disease (2010)
  • Research & Publications +

    Selected Publications

    1. Stephens RS, Servinsky LE, Rentsendorj O, Kolb TM, Pfeifer A, Pearse DB. Protein Kinase G increases antioxidant function in lung microvascular endothelial cells by inhibiting the c-Abl tyrosine kinase. Am J Physiol Cell Physiol. 2014 Jan 8. [Epub ahead of print] PMID: 24401847
    2. Stephens, R.S., and Fan, E. Choosing Wisely – When to Mend a Broken Heart with ECMO? Critical Care 2014. In Press.
    3. Stephens, R.S., Shah, A.S., and Whitman, G.J.R. Should we prone cardiac surgical patients with severe acute respiratory distress syndrome (reply)? Annals of Thoracic Surgery 2014. 97(3): 1122-3.
    4. Kim, BS, Serebreni, L, Hamdan, O, Wang, L, Parniani, A, Sussan, T, Stephens, RS, Boyer, L, Damarla, M, Hassoun, PM, and Damico, R. Xanthine Oxidoreductase is a Critical Mediator of Cigarette Smoke-Induced Endothelial Cell DNA Damage and Apoptosis. Free Radical Biology and Medicine 2013. 60: 336-46.
    5. Stephens RS, Shah AS, Whitman GJ. Lung injury and acute respiratory distress syndrome after cardiac surgery. Ann Thorac Surg. 2013 Mar;95(3):1122-9. doi: 10.1016/j.athoracsur.2012.10.024. Epub 2013 Jan 23. Review. PMID: 23352419
    6. Rahimi RA, Skrzat J, Reddy DR, Zanni JM, Fan E, Stephens RS, Needham DM. Physical rehabilitation of patients in the intensive care unit requiring extracorporeal membrane oxygenation: a small case series. Phys Ther. 2013 Feb;93(2):248-55. doi: 10.2522/ptj.20120336. Epub 2012 Oct 25. PMID: 23104895
    7. Anidi IU, Servinsky LE, Rentsendorj O, Stephens RS, Scott AL, Pearse DB. CD36 and Fyn kinase mediate malaria-induced lung endothelial barrier dysfunction in mice infected with Plasmodium berghei. PLoS One. 2013 Aug 15;8(8):e71010. doi: 10.1371/journal.pone.0071010. eCollection 2013. PMID: 23967147 [PubMed - in process]
    8. Stephens, RS, Rentsendorj, O, Servinsky, LE, Moldobaeva, A, Damico, R, Pearse DB. cGMP Increases Anti-Oxidant Function and Attenuates Oxidant Cell Death in Mouse Lung Microvascular Endothelial Cells by a Protein Kinase G-Dependent Mechanism. Am J Physiol Lung Cell Mol Physiol. 2010. 299(3):L323-33.
    9. Petrache, I, Diab, K, Knox, KS, Twigg, HL, Stephens, RS, Flores, S, Tuder, RM. HIV-Associated Pulmonary Emphysemia: A Review of the Literature and an Inquiry into its Mechanism. Thorax 2008. 63(5):463-9.
    10. Moldobaeva, A., Welsh-Servinsky, L.E., Shimoda, L.A., Stephens, R.S., Verin, A.D., Tuder, R.M., and Pearse, D.B. Role of Protein Kinase G in Barrier Protective Effects of cGMP in Human Pulmonary Artery Endothelial Cells. Am Journal Physiol: Lung Cell Mol Physiol 2006. 290(5):L919-30.
    11. Kinnery, P., Pick, J., Stephens, S., Jain, D., Solomides C.S., Niven, R., Segal, R., Christofidou-Solomidou, M. (2006). KL4-Surfactant prevents Hyperoxic and LPS-Induced Lung Injury in Mice. Pediatric Pulmonology. 41(10):916-28.
    12. Stephens, S., Beyer, B., Balthazar-Stablein, U., Duncan, R., Kostacos, M., Lukoma, M, Green, G.R., and Poccia, D. (2002). Two Kinase Activities are Sufficient for Sea Urchin Sperm Chromatin Decondensation in Vitro. Molecular Reproduction and Development.62: 496-503.
  • Academic Affiliations & Courses +
  • Activities & Honors +


    • American Physiologic Society
    • American Thoracic Society
  • Videos & Media +
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