Regulation of hypothalamic cell fate specification and function; Functional analysis of candidate regulators of cell specification and survival in retina; High throughput screening; Molecular basis of neuronal and glial cell fate specification and survival
Dr. Seth Blackshaw is an assistant professor of neuroscience, neurology and opthalmology at the Johns Hopkins University School of Medicine. Additionally, he serves as an assistant investigator in both the High Throughput Biology Center and the Institute for Cell Engineering at Johns Hopkins.
His work examines the molecular basis of neuronal and glial cell fate specification and survival. Dr. Blackshaw has catalogued all of the messenger RNAs expressed during development of the mouse retina. His research focuses on functionally characterizing the network of genes that control specification of different cell types within the retina. His goal is to extend these studies to an understanding of more elaborate brain structures, such as the hypothalamus, that are also critical regulators of behavior.
Dr. Blackshaw received a B.A. in biology and an M.S. in biochemistry from the University of Chicago in 1991. He completed his Ph.D. in neurosciences at Johns Hopkins in 1997 and subsequently conducted two postdoctoral fellowships, one in neuroscience at Johns Hopkins and a second in genetics at the Harvard University Medical School. He joined the Hopkins faculty in 2004.
Dr. Blackshaw has authored or co-authored more than 75 peer-reviewed publications and holds several patents and copyrights. His work has garnered numerous grants and awards, including the W. M. Keck Foundation Distinguished Young Scholar in Medial Research Award, the Klingenstein Fellowship, the Basil O’Connor Starter Scholar Award and the Ruth and Milton Steinbach Fund Award for Research in Macular Degeneration. He is a member of the Society for Developmental Biology and the Society for Neuroscience, and serves on the editorial boards of Biomolecules and Frontiers of Systems Biology.