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Charlotte A. Gaydos, PhD

Director, Johns Hoopkins Center for the Development of Point Of Care Tests for Sexually Transmitted Diseases
Joint of Emergency Medicine

See Research on Pubmed

Female

Titles

  • Director, Johns Hoopkins Center for the Development of Point Of Care Tests for Sexually Transmitted Diseases
  • Joint Appointment in Emergency Medicine
  • Joint of Emergency Medicine
  • Professor of Medicine

Centers & Institutes

  • Center for Global Health

Research Interests

Chlamydia trachomatis; C. pneumoniae; C. psittaci. Trichomonas vaginalis; Neissseria gonorrhoeae; Mycoplasma genitalium

Biography

Dr. Charlotte Gaydos is a Professor in the Division of Infectious Diseases, Medicine, Johns Hopkins University with joint appointments in Emergency Medicine, Epidemiology, and Population, Family and Reproductive Health, School of Public Health. She is the Director of the International STD, Respiratory Diseases, and Biothreat Research Laboratory.  She received her B.S. in medical technology and her M.S. in medical microbiology from West Virginia University.  Her MPH. and DPH were received from Johns Hopkins University School of Public Health. She has 45 years laboratory expertise in microbiology, has authored 22 book chapters, 350 research articles, and >500 abstracts/oral presentations.   Dr. Gaydos has conducted clinical trials for new diagnostics for C. trachomatis, N. gonorrhoeae and T. vaginalis.  Her research has included developing DNA amplification tests for C. trachomatis, C. pneumoniae, C. psittaci, T. vaginalis, N. gonorrhoeae, M. genitalium and the agents of genital ulcer disease.  An Internet project for home chlamydia screening using self-obtained urogenital samples and return mail has been an effective program for reaching women and men who may not attend clinics to be tested for STDs. Her laboratory is the International Core Diagnostic Laboratory and Reference Laboratory for many collaborative epidemiologic and behavioral studies of STDs, respiratory diseases, and trachoma. She is Co-investigator for the Diagnostic Core for the Mid-Atlantic Center of Excellence for Biothreat and Emerging Infectious Diseases. She is the recipient of an NIBIB, NIH Center grant to develop and test point-of-care tests for STDs, The laboratory is CAP/CLIA-licensed for diagnostic assays.  Dr. Gaydos serves on the Executive Boards of the American Sexually Transmitted Diseases Association (ASTDA) and International Society for Sexually Transmitted Diseases Research (ISSTDR); and serves on the Editorial Board for the STD Journal. She is Chairman of the Research Translational Committee of National Chlamydia Coalition.

Languages

  • English
Additional Resources +
  • Education +

    Education

    • B.S., West Virginia University, Morgantown, WV, 1964
    • M.S., West Virginia University, Morgantown, WV, 1966
    • M.P.H., Johns Hopkins University, Baltimore, MD, 1989
    • Ph.D., Johns Hopkins University, Baltimore, MD, 1993
  • Research & Publications +

    Selected Publications View all on PubMed

    Gaydos CA. Barnes MR, Quinn N, Jett-Goheen, Hsieh Y-H. Trichomonas vaginalis infection in men who submit self-collected penile swabs after internet recruitment. Sex Transmit Dis. (epub ahead of print January 26, 2013 as 10.1136/sextrans-2012-050946). PMID: 23354525

    Jeng K, Hardick J, Rothman R, Yang S, Won H, Peterson S, Hsieh Y-H, Masek B, Carroll K, Gaydos CA. RT-PCR/ESI-MS for Rapid Detection of Biothreat and Common Respiratory Pathogens. J Clin Microbiol (in press).

    Gaydos CA, Van Der Pol B, Jett-Goheen M, Barnes M, Quinn N, Clark C, Daniel GE, Dixon PB, Hook III EW, CT/NG Study Group. Performance of the Cepheid CT/NG Xpert Rapid PCR Test for the Detection of Chlamydia trachomatis and Neisseria gonorrhoeae. J Clin Microbiol 51:1666-1672, 2013. PMCID: PMC3716060.

    Gaydos CA, Solis M, Hsieh Y-H, Jett-Goheen M, Nour S, Rothman R. Use of Tablet-Based Kiosks in the Emergency Department to Guide Patient HIV Self-Testing with a Point-of-Care Oral Fluid Test. Inter J STD Aids. DOI: 10.1177/0956462413487321

    Pearce DM, Styles DN, Hardick JP, Gaydos CA. A new rapid molecular point-of-care assay for Trichomonas vaginalis: preliminary performance data. Sex Transmit Dis (in press) April 20, 2013 as 10.1136/sextrans-2012-051000.

    Murillo L, Hardick J, Jeng K, Gaydos CA. Evaluation of the Pan Influenza detection kit utilizing the PLEX-ID and influenza samples from the 2011 respiratory season. J Vir Methods 193:173-176, 2013.

    Melendez JH, Huppert J, Jett-Goheen, Hesse E, Quinn N, Gaydos CA, Geddes CD. Blinded Evaluation of the Microwave-Accelerated Metal-Enhanced Fluorescence (MAMEF) Ultra-Rapid and Sensitive Chlamydia Trachomatis Test Using Clinical Samples. J Clin Microbiol (in press).

    Gaydos CA, Barnes M, Jett-Goheen M, Quinn N, whittel P, Hogan T, Hsieh Y_h. Characteristics and predictors of women who obtain rescreening for sexually transmitted infections using www.iwantthekit.org screening program. Internat J STD & AIDS. online July 15, 2013 DOI: 10.1177/0956462483252

    Tang YW, Lowery KS, Valsamakis A, Schaefer VC, Chappell JD, White-Abell J, Quinn CD, Li H, Washington CA, Cromwell J, Giamanco CM, Forman M, Holden J, Rothman RE, Parker ML, Ortenberg EV, Zhang L, Lin YL, Gaydos CA. Clinical Accuracy of a PLEX-ID Flu Device for Simultaneous Detection and Identification of Influenza Viruses A and B. J Clin Microbiol. 51:40-45, 2013. PMCID: PMC3536229.

    Lab

    The International Sexually Transmitted Diseases (STD), Respiratory, and Biothreat and Emerging Diseases Research Laboratory

    The International Sexually Transmitted Diseases (STD), Respiratory, and Biothreat and Emerging Diseases Research Laboratory conducts research, but is also a clinical and diagnostic laboratory. Our laboratory is recognized internationally for expertise as a reference laboratory for STDs, especially Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma genitalium, HSV, HPV, and syphilis, as well as for respiratory diseases including Streptococcus pneumoniae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and viral respiratory infections. The laboratory has served as the Core Diagnostic Laboratory and as the Reference Laboratory for many national and international grants for collaborative studies of STDs. In collaboration with the University of Maryland and the Emergency Department of Johns Hopkins University, the laboratory has been performing and analyzing diagnostic PCRs of CSF, blood, joint, and peritoneal fluids for biothreat agents as well as for more common agents of bacteremia, meningitis and infections of sterile body fluids. The laboratory is licensed by the State of Maryland and is CLIA approved. The International Laboratory is also the home of The Johns Hopkins Center for Point-of-Care Tests for Sexually Transmitted Diseases. Our Mission is to conduct in-house clinical testing of point-of-care (POC) devices, collaborate with scientists and engineers on exploratory technology development projects, complete clinical needs assessments of STD public health care professionals, and provide training to technology developers on clinical issues related to the development of POC devices for STDs. We also create and test unique methods for the diagnosis of sexually transmitted diseases, including Internet recruitment for home collection of urogenital samples sent by mail for testing by the laboratory, including eventual delivery of over-the-counter tests (OTC) POC tests for STDs to end users via the Internet. We are developing novel approaches for measuring acceptability and accuracy of available POC-type assays, such as for HIV and trichomonas, in primary care settings with comparisons between trained and untrained users.

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    Dr. Gaydos, Awarded American Sexually Transmitted Diseases Association Achievement award , 2008

    Professional Activities

    American Sexually Transmitted Diseases Society, Executive Board 2007-present

    International Society for Sexually Transmitted Diseases Research (ISSTDR), Executive Board 2007-present.

    International Union of Sexually Transmitted Infections (IUSTI) North American ,Representative 2006-7

    International Union of Sexually Transmitted Infections (IUSTI), Director, North American Region 2008-present; President Elect World IUSTI
  • Videos & Media +

    Video Links

    Lectures and Presentations

    Gaydos, CA. E-Health for STI Control, 2011 Australasian Sex Health Conf. (invited plenary talk) Sept 28-30, 2011, Canberra, Australia.

    Gaydos, CA. New Diagnostics. (plenary lecture) IUSTI World Congress, New Dehli, India Nov. 2-4, 2011.

    Gaydos, CA. What is new in POC tests for STIs? Can we treat more STIs with POC tests? IUSTI World Congress, New Dehli, India Nov. 2-4, 2011

    Gaydos CA, Trichomonas infections: Time to do better for our patients. ( invited talk) Gen-Probe Satellite Symposium. 22nd ECCMID, London, UK. Mar 31- April 4, 2012.

    Gaydos CA. Trichomonas: The Undervalued But Most Prevalent STI with Value-Added (invited talk) BASHH-ASTDA 4th Joint Meeting, Brighton, England, June 26- 29th, 2012

    Gaydos CA,EPT: To Be or Not To Be? (invited talk),13th IUSTI World Congress, Melbourne, Australia Oct 15-17, 2012.

    Gaydos, CA. New technologies in STI diagnosis and control: Promising future. Invited plenary Oral PL05.2 STI & AIDS World Congress, Vienna, Austria, July 14-17, 2013. Sex Transm Infect. 89S: p. A5, 2013.

    Gaydos CA. I Want The Kit: A Free Home-Based STI Testing (and Re-testing) Resource for Your Patients. (invited lecture) Maryland 2013 Annual STI Update, June 5, 2013

  • Upcoming Events +

    Grand Rounds Lectures

    Gaydos, C.A., Can we use the Internet to screen adolescents for Chlamydia? Satisfaction and results of the www.iwantthekit.org. Pediatric Grand Rounds, University of Texas Medical Branch, Dept. Pediatrics, Galveston, TX, January 18, 2008.

    Gaydos CA.E-technology, the Internet, and the Chlamydia Epidemic. Medical Grand Rounds, Johns Hopkins University Dept. Med. Sept 26, 2008.

    Gaydos CA. Using Internet e-technology to address the epidemic of chlamydia. Grand Rounds, OB/GYN, University of Cincinnati Medical Center, March 20, 2009.

  • Contact & Locations +

    Department/Division

    • Emergency Medicine
    • Medicine - Infectious Diseases

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