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Photo of Dr. Nestoras Mathioudakis

Nestoras Nicolas Mathioudakis, M.D.

Director, Inpatient Diabetes Management Service
Assistant Professor of Medicine

Male

Appointment Phone

410-955-9270

Main Location

Johns Hopkins Outpatient Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Director, Inpatient Diabetes Management Service
  • Assistant Professor of Medicine

Centers & Institutes

Departments

  • Medicine - Endocrinology, Diabetes and Metabolism

Locations

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-955-9270

2360 W. Joppa Road
Joppa Concourse Suite 212
Lutherville, MD 21093 map
Phone: 410-955-2908
Fax: 410-614-9586

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-9270

601 N. Caroline Street
Baltimore, MD 21287 map
Phone: 410-955-2908
Fax: 410-614-9586

Contact for Research Inquiries

Phone: 410-955-2908

Expertise

Adrenal Disorders, Diabetes, Diabetes Mellitus, Diabetic Foot Care, Diabetic Foot Ulcers, Endocrinology , Gonadal Disorders, Hypopituitarism, Pituitary Disorders, Pituitary Tumors, Thyroid Disorders

Research Interests

patient safety and quality; inpatient glucose management; type 2 diabetes mellitus; diabetic foot ulcers

Biography

A board-certified endocrinologist, Dr. Mathioudakis focuses his clinical practice on the care of patients with endocrine disorders, with a particular clinical interest and research focus on diabetes mellitus.   His main research focus is on discovering ways to improve patient safety and quality among hospitalized patients with diabetes.  He is the Endocrine Director of the Johns Hopkins Multidisciplinary Diabetic Foot and Wound Clinic and is actively investigating the causes and treatment of diabetic foot ulcers.  In addition, Dr. Mathioudakis has a basic science and clinical research background in pituitary tumors.  Dr. Nestoras Mathioudakis graduated from the Johns Hopkins University School of Medicine and trained in Internal Medicine at Johns Hopkins Bayview Medical Center.  He did a fellowship in Endocrinology, Diabetes, & Metabolism at the Johns Hopkins Hospital and then joined the faculty in this division in 2012. 

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    Additional Information

  • Education +
    • B.A., Johns Hopkins University (Maryland) (2001)
    • M.D., Johns Hopkins University School of Medicine (Maryland) (2006)
  • Research & Publications +

    Clinical Trials:

    • Diabetes Prevention Program Outcomes Study (DPPOS), Co-PI

    Clinical Trial Keywords: diabetes prevention

    Selected Publications View all on PubMed

    1. Wu S, Powell J, Mathioudakis N, Kane S, Fernandez E, Sears CL. Bacteroides fragilis enterotoxin induces intestinal epithelial cell secretion of interleukin-8 through mitogen-activated protein kinases and a tyrosine kinase-regulated nuclear factor kappa B pathway. Infect Immun. 2004 Oct;72(10):5832-9.
    2. Pendleton C, Adams H, Mathioudakis N, Quinones-Hinojosa, A. Sellar Door: Harvey Cushing’s Entry Into the Pituitary Gland, the Unabridged Hopkins Experience 1896-1912. World Neurosurg 2011 Nov 10.
    3. Mathioudakis N, Pendleton C, Quinones-Hinojosa A, Wand G, Salvatori R. ACTH-secreting Pituitary Adenomas: Size Does Not Correlate With Hormonal Activity. Pituitary 2011 Nov 5
    4. Mathioudakis N, Thapa S, Wand GS, Salvatori R. ACTH-secreting pituitary microadenomas are associated with a higher prevalence of central hypothyroidism compared to other microadenoma types.Clin Endocrinol (Oxf). 2012 May 15.
    5. Mathioudakis N, Sundaresh R, Larsen A, Ruff W, Schiller J, Guerrero CázaresH, Burger P, Salvatori R, Quiñones-HinojosaA, Expression of the pituitary stem/progenitor marker GFRα2 in human pituitary adenomas and normal pituitary, Pituitary 2014 Jan 9.
    6. Mathioudakis N, Salvatori R. Adult-onset growth hormone deficiency: causes, complications, and treatment options. Curr Opin Endocrinol Diabetes Obes. 2008 Aug;15(4):352-8.
    7. Mathioudakis N, Salvatori R. Pituitary tumors. Curr Treat Options Neurol. 2009 Jul;11(4):287-96.
    8. Mathioudakis N, Ball D. Acromegaly. The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Technology Center), Baltimore, MD. Sept 2010.
    9. Mathioudakis N, Ball D. Glucagonoma. The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Information Technology Center), Baltimore, MD, June 2010.
    10. Salvatori R, Mathioudakis N. Expert Column: Diagnosing Patients with Acromegaly and Evaluating Available Treatment Options. Medscape CME Online, August 2011.
    11. Mathioudakis N, U-500 insulin. The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Information Technology Center), Baltimore MD, August 2013.
    12. Mathioudakis N, Insulin pumps. The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Information Technology Center), Baltimore MD, August 2013.
    13. Mathioudakis N, Global Health and Diabetes. The Johns Hopkins Diabetes Guide POC-IT Center (Johns Hopkins Point of Care Information Technology Center), Baltimore MD, August 2013.
    14. Xing JC, Bishop JA, Mathioudakis N, Agrawal N, Tufano RP. A large nonmetastatic anaplastic thyroid cancer with complete thyroidal confinemtn. Case Report Med. 2011;2011:584978.
    15. Mathioudakis N, Quinones-Hinojosa A, Salvatori R, Basaria S. A lifelong smoker with hypopituitarism: rethinking the hypothesis of a tumor in the hypophysis. Case Report Med. 2012;2012:853568. Epub 2012 Apr 22.
    16. Mathioudakis N, Salvatori R. Medical therapy of hormone-secreting pituitary adenomas. In Schmidek & Sweet’s Operative Neurosurgical Techniques: Indications, Methods, and Results. Ed. A Quinones-Hinojosa, 2012
    17. Mathioudakis N, Mathioudakis N, Salvatori R. Management Options for Persistent Postoperative Acromegaly. In Neurosurgery Clinics of North America, Ed. Aghi and Blevins
    18. Mathioudakis N, Salvatori R. Management Options for Persistent Postoperative Acromegaly, Neurosurg Clin N Am. 2012 Oct;23(4):621-38.
  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    • Phi Beta Kappa, Johns Hopkins University, 1999
    • Departmental Honors, Johns Hopkins University, 2001
    • Leonie Shorey Scholar, Johns Hopkins University, 2001
    • First Place Oral Clinical Vignette, American College of Physicians, 2009
    • Endocrinology Mentor of the Year Award, 2012

    Memberships

    • American Association of Clinical Endocrinologists (AACE)
    • American Diabetes Association (ADA)
    • Endocrine Society
    • PRIDE (Planning Research in Inpatient Diabetes)

    Professional Activities

    • Endocrinology Inpatient Consulting Attending
    • General Endocrinology Outpatient Clinic
    • Diabetes Center Outpatient Clinics
    • Education (medical students, residents, fellows)
    • Preceptor, Johns Hopkins Endocrinology, Diabetes & Metabolism Fellows' Outpatient Clinic
  • Videos & Media +

    Lectures and Presentations

    Hyperglycemic Emergencies
    Noon Conference Series , Baltimore, MD (08/01/2012)
    Johns Hopkins Bayview Medical Center

    Diabetes Mellitus: Core Lecture
    Physician Assistant Residency Program , Baltimore, MD (10/01/2012)
    Johns Hopkins Hospital

    Diabetes
    Medicine Core Clerkship , Baltimore, MD (09/01/2013)
    Johns Hopkins School of Medicine

    Thyroid Disorders
    Core Lecture , Baltimore, MD (11/01/2013)
    Johns Hopkins School of Nursing

    Thyroid Nodules and Cancer
    Lecture , Genes to Society Course , Baltimore, MD (12/01/2013)
    Johns Hopkins School of Medicine

    Ectopic ACTH syndrome
    Maryland Endocrine Society Meeting , Baltimore, MD (02/01/2011)
    Union Memorial Hospital

    Prevention of Type 2 Diabetes Mellitus in 2013
    Lecture to Employees and clients of Butterfield Bank , Bermuda (05/01/2013)
    Butterfield Bank

    Insulin Therapy in Type 2 Diabetes
    Department of Medicine Grand Rounds , Kuwait (09/01/2012)
    Al Adan Hospital

    Principles in Insulin Pump Management
    Department of Medicine Grand Rounds , Kuwait (09/01/2012)
    Al Adan Hospital

    Diabetic Nephropathy: Current Understanding and Standards of Care
    Endocrine Grand Rounds , Baltimore, MD (10/01/2012)
    Johns Hopkins Hospital

    Prevention of Type 2 Diabetes in 2013
    Medical Grand Rounds , San Fernando, Trinidad and Tobago (01/01/2012)
    San Fernando General Hospital

    Top 10 Inpatient Glycemic Management Errors at Johns Hopkins Hospital in 2012
    Endocrine Grand Rounds , Baltimore, MD (04/01/2013)
    Johns Hopkins Hospital

    Medical Strategies for the Diabetic Foot Ulcer
    Endocrine Grand Rounds , Baltimore, MD (10/01/2013)
    Johns Hopkins Hospital

    Insulin Therapy in Type 2 Diabetes
    Department of Medicine Grand Rounds , Kuwait (01/01/2012)
    Al Adan Hospital

    Principles in Insulin Pump Management
    Department of Medicine Grand Rounds , Kuwait (01/01/2012)
    Al Adan Hospital

    Diabetic Nephropathy, Current Understanding and Standards of Care
    Endocrine Grand Rounds , Baltimore (01/01/2012)
    Johns Hopkins Hospital

    Prevention of Type 2 Diabetes in 2013
    Medical Grand Rounds , San Fernando (01/01/2012)
    San Fernando General Hospital

    Top 10 Inpatient Glycemic Management Errors at Johns Hopkins Hospital in 2012
    Endocrine Grand Rounds , Baltimore (01/01/2013)
    Johns Hopkins Hospital

    Medical Strategies for the Diabetic Foot Ulcer
     Endocrine Grand Rounds , Baltimore (01/01/2013)
    Johns Hopkins Hospital

    Recent News Articles & Media Coverage

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