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Aaron Andrew Ross Tobian, M.D., Ph.D.
Director of Transfusion Medicine
Associate Professor of Pathology
Research Interests: Human papillomavirus (HPV); Genital herpes (HSV-2); Human immunodeficiency virus (HIV); Male circumcision; Sexually transmitted infections; Allergic transfusion reactions; Epidemiologic risk factors; Transfusion medicine; Epidemiology; Pathobiology ...read more
The Johns Hopkins Hospital (Main Entrance)
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Johns Hopkins Bayview Medical Center
4940 Eastern Avenue
Baltimore, MD 21224 map
Contact for Research Inquiries
Department of Pathology
600 N. Wolfe St.
Baltimore, MD 21287 map
Dr. Aaron Tobian is an Associate Professor of Pathology and Medicine at the Johns Hopkins University School of Medicine.
His research is largely focused on two areas of adverse events associated with blood transfusion: allergic transfusion reactions (the most common transfusion complication) and the epidemiologic risk factors of human immunodeficiency virus (HIV) and transfusion transmitted infections.
Dr. Tobian is highly involved in the transfusion medicine community. He is Editor-in-Chief of the website Transfusion News, an Associate Editor of the Journal of Clinical Apheresis, Editorial Board member for the journal Transfusion, and Chair of AABB’s Clinical Transfusion Medicine Committee.
Dr. Tobian also serves on the faculty of the Center for Global Health, where he is Principal Investigator of studies being conducted in four African nations.
He earned his medical and doctoral degrees at Case Western Reserve University School of Medicine. He completed both a pathology residency and a transfusion medicine fellowship at Johns Hopkins.
- Director of Transfusion Medicine
- Associate Professor of Pathology
- Joint Appointment in Medicine
- MD, Case Western Reserve University School of Medicine (2006)
- Johns Hopkins University School of Medicine / Pathology (2009)
- Johns Hopkins University School of Medicine / Transfusion Medicine (2010)
- American Board of Pathology / Clinical Pathology (2009)
- American Board of Pathology / Pathology-Transfusion Med (2013)
Research & Publications
Dr. Tobian’s research team is focused on two main areas of adverse events associated with transfusion:
- Evaluation of the biological mechanisms of allergic transfusion reactions—the most common complication of blood transfusion—and methods to prevent these reactions
- Evaluation of the epidemiologic risk factors of HIV and other sexually transmitted infections
In collaboration with Uganda’s Rakai Health Sciences Program (RHSP), Dr. Tobian’s team has established a research program to evaluate these factors.
Working closely with the RHSP, the investigators are evaluating the efficacy of male circumcision in preventing sexually transmitted infections in men and their female partners. In addition, using foreskin mucosal tissue, they are assessing the genital cellular immune milieu associated with sexually transmitted infections to develop novel HIV prevention therapies.
Selected PublicationsView all on Pubmed
Tobian AAR, Serwadda D, Quinn TC, Kigozi G, Gravitt PE, Laeyendecker O, Charvat B, Ssempijja V, Riesdel M, Oliver AE, Nowak RG, Moulton LH, Chen MZ, Reynolds SJ, Wawer MJ, Gray RH. Male circumcision for the prevention of HSV-2 and HPV infections and syphilis. N Engl J Med 2009; 360:1298-309.
Tobian AAR and Gray RH. The medical benefits of male circumcision. JAMA. 2011; 306: 1479-1480.
Grabowski MK, Gray RH, Makumbi F, Kagaayi J, Redd AD, Kigozi G, Reynolds SJ, Nalugoda F, Lutalo T, Wawer MJ, Serwadda D, Quinn TC, Tobian AAR. Use of injectable hormonal contraception and women's risk for herpes simplex virus type 2 acquisition: a prospective study of couples in Rakai, Uganda. Lancet Global Health. 2015; 3:e478-86.
Goel R, Ness PM, Takemoto C, King KE, Krishnamurti L, and Tobian AAR. Platelet transfusions in platelet consumptive disorders are associated with in-hospital arterial thrombotic complications and mortality. Blood. 2015; 125(9):1470-1476.
Kaufman RM, Djulbegovic B, Gernsheimer T, Kleinman S, Tinmouth AT, Capocelli KE, Cipolle MD, Cohn CS, Fung MK, Grossman BJ, Mintz PD, OMalley BA, Sesok-Pizzini DA, Shander A, Stack GE, Webert KE, Weinstein R, Welch BG, Whitman GJ, Wong EC, and Tobian AAR. Platelet transfusion: a clinical practice guideline from the AABB. Annals of Internal Medicine. 2015; 162:205-213.
Academic Affiliations & Courses
Graduate Program Affiliation