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Aaron Andrew Ross Tobian, MD PhD

Associate Professor of Pathology
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Johns Hopkins Bayview Medical Center

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  • Associate Professor of Pathology

Centers & Institutes

  • Comprehensive Transplant Center
  • Global Health, Center for



Research Interests

Pathobiology; Epidemiology; Transfusion medicine; Epidemiologic risk factors; Allergic transfusion reactions; Sexually transmitted infections; Male circumcision; Human immunodeficiency virus (HIV); Genital herpes (HSV-2); Human papillomavirus (HPV)


Dr. Aaron Andrew Ross Tobian is an associate professor of pathology at the Johns Hopkins University School of Medicine.

His research is largely focused on two blood transfusion-related adverse events: allergic transfusion reactions (the most common transfusion complication) and the epidemiologic risk factors of human immunodeficiency virus (HIV) and other sexually transmitted infections.

Dr. Tobian also serves on the faculty of the Center for Global Health, where he is leading an international study of oncogenic human papillomavirus (HPV), mucosal immune response and the risk of HIV acquisition.

He earned his medical and doctoral degrees at Case Western Reserve University School of Medicine. He completed both a pathology residency and a transfusion medicine fellowship at Johns Hopkins.


  • English
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  • Education +


    • Case Western Reserve University School of Medicine (Cleveland OH) (2006)
    • Case Western Reserve University School of Medicine (Cleveland OH) (2004)


    • Johns Hopkins University School of Medicine / Pathology (Baltimore MD) (2009)


    • Johns Hopkins University School of Medicine / Transfusion Medicine (Baltimore MD) (2010)


    • American Board of Pathology / Clinical Pathology (2009)
  • Research & Publications +

    Research Summary

    Dr. Tobian’s research team is focused on two main areas of adverse events associated with transfusion:

    • Evaluation of the biological mechanisms of allergic transfusion reactions—the most common complication of blood transfusion—and methods to prevent these reactions
    • Evaluation of the epidemiologic risk factors of HIV and other sexually transmitted infections

    In collaboration with Uganda’s Rakai Health Sciences Program (RHSP), Dr. Tobian’s team has established a research program to evaluate these factors.

    Working closely with the RHSP, the investigators are evaluating the efficacy of male circumcision in preventing sexually transmitted infections in men and their female partners.

    In addition, using foreskin mucosal tissue, they are assessing the genital cellular immune milieu associated with sexually transmitted infections to develop novel HIV prevention therapies.

    Selected Publications

    1. Tobian AAR and Gray RH. “The medical benefits of male circumcision.” JAMA. 2011; 306: 1479-1480.
    2. Tobian AAR, Kong X, Wawer MJ, Kigozi G, Gravitt PE, Serwadda D, Eaton K, Nalugoda F, Quinn TC, Gray RH. “Circumcision of HIV-infected men and human papillomavirus transmission to female partners: analyses of data from a randomised trial in Rakai, Uganda.” Lancet Infectious Diseases. 2011; 11: 604-612.
    3. Tobian AAR, Savage WJ, Tisch DJ, Thoman S, King KE, and Ness PM. “Prevention of allergic transfusion reactions to platelets and red blood cells through plasma reduction.” Transfusion. 2011; 51: 1676-1683.
    4. Tobian AAR, Serwadda D, Quinn TC, Kigozi G, Gravitt PE, Laeyendecker O, Charvat B, Ssempijja V, Riesdel M, Oliver AE, Nowak RG, Moulton LH, Chen MZ, Reynolds SJ, Wawer MJ, Gray RH. “Male circumcision for the prevention of HSV-2 and HPV infections and syphilis.” N Engl J Med 2009; 360:1298-309.
    5. Tobian AAR, King KE, Ness PM. “Transfusion premedications: a growing practice not based on evidence.” Transfusion 2007; 47:1089-1096.
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    Graduate Program Affiliation


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    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    Baltimore, MD 21224
    Appointment Phone: 410-955-6583
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    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Hospital Main Entrance - Sheikh Zayed Tower
    Baltimore, MD 21287
    Appointment Phone: 410 955 6583
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    • Pathology

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