Skip Navigation
Search Menu
Find an Expert


Khaled Mahmoud El-Shami, M.B.Ch.B., Ph.D.

Photo of Dr. Khaled Mahmoud El-Shami, M.B.Ch.B., Ph.D.


Languages: English, Arabic

Expertise: Acute Leukemia, Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), Hematologic Malignancies, Leukemia, Lymphoma, Medical Oncology, Myelodysplastic Syndromes (MDS), Myelodysplastic/Myeloproliferative Neoplasms, Myeloma more

Research Interests: Drug development in myeloid malignancies; immunotherapy of hematologic cancers; hematologic malignancies; acute leukemias; chronic leukemias; myelodysplastic syndromes; myeloprolifetive neoplasms; lymphomas more


Sidney Kimmel Cancer Center at SMH

5255 Loughboro Rd NW
First Fl Bldg B
Washington, DC 20016 map
Phone: 202-660-6500
Fax: 202-660-6501


Khaled M. El-Shami, M.B.Ch.B., Ph.D., is a medical oncologist at Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital in Washington, D.C. Dr. El-Shami is board certified in medical oncology by the American Board of Internal Medicine. 

Dr. El-Shami's clinical interests are in hematologic malignancies, including leukemias, lymphomas and myelomas, as well as gastrointestinal cancers and melanoma.

Dr. El-Shami graduated from Alexandria University Faculty of Medicine in Alexandria, Egypt. He was a Chevening Scholar as a M.S. student in molecular genetics at the University of Sussex in the United Kingdom, as well as a Sam Cohen Windhoek Scholar as a Ph.D. student in cancer immunology at the Weizmann Institute in Israel. Dr. El-Shami also completed a postdoctoral fellowship at the National Cancer Institute, a residency in internal medicine at George Washington University School of Medicine and a fellowship in medical oncology at Johns Hopkins University School of Medicine.

Dr. El-Shami served as faculty at Georgetown University and George Washington University prior to joining the Division of Hematologic Malignancies at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center.

Dr. El-Shami's research focus is on hematologic malignancies, including acute and chronic leukemias, myelodysplastic syndromes, myeloprolifetive neplasms and lymphomas. more

Departments / Divisions



  • MBChB, Alexandria University (1988)


  • Alexandria University Hospital / Surgery (1992)
  • George Washington University School of Medicine / Internal Medicine (2005)


  • Johns Hopkins University School of Medicine / Oncology (2008)

Board Certifications

  • American Board of Internal Medicine / Medical Oncology (2007)

Research & Publications

Selected Publications

View all on Pubmed

Hossain, A., Rafei, H., Jariwala, A., El-Shami, K. "A rare breed: Wild-type braf and ighv expression in a 29 year old lady with classical hairy cell leukemia." Leuk Res Rep. 2017 Jan 24;7:20-22. doi: 10.1016/j.lrr.2017.01.001. eCollection 2017.

El-Shami, K., Oeffinger, K.C., Erb, N.L., Willis, A., Bretsch, J.K., Pratt-Chapman, M.L., Cannady, R.S., Wong, S.L., Rose, J., Barbour, A.L., Stein, K.D., Sharpe, K.B., Brooks, D.D., Cowens-Alvarado, R.L. "American Cancer Society Colorectal Cancer Survivorship Care Guidelines." CA Cancer J Clin. 2015 Nov-Dec;65(6):428-55. doi: 10.3322/caac.21286. Epub 2015 Sep 8. Review.

Zheng, L., Edil, B.H., Soares, K.C., El-Shami, K., Uram, J.N., Judkins, C., Zhang, Z., Onners, B., Laheru, D., Pardoll, D., Jaffee, E.M., Schulick, R.D. "A safety and feasibility study of an allogeneic colon cancer cell vaccine administered with a granulocyte-macrophage colony stimulating factor-producing bystander cell line in patients with metastatic colorectal cancer." Ann Surg Oncol. 2014 Nov;21(12):3931-7. doi: 10.1245/s10434-014-3844-x. Epub 2014 Jun 19.

Parikh, S.A., Kantarjian, H., Schimmer, A., Walsh, W., Asatiani, E., El-Shami, K., Winton, E., Verstovsek, S. "Phase II study of obatoclax mesylate (GX15-070), a small-molecule BCL-2 family antagonist, for patients with myelofibrosis." Clin Lymphoma Myeloma Leuk. 2010 Aug;10(4):285-9. doi: 10.3816/CLML.2010.n.059.

El-Shami, K., Stone, R.M., Smith, B.D. "FLT3 inhibitors in acute myeloid leukemia." Expert Rev Hematol. 2008 Dec;1(2):153-60. doi: 10.1586/17474086.1.2.153. Review.

Is this you? Edit Profile