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Junghoon Lee, M.S., Ph.D.

Photo of Dr. Junghoon Lee, M.S., Ph.D.

Assistant Professor of Radiation Oncology and Molecular Radiation Sciences

Research Interests: Medical image processing and analysis

Contact for Research Inquiries

Johns Hopkins University School of Medicine
401 North Broadway
Radiation Oncology and Molecular Radiation Sciences
Baltimore, MD 21231 map
Phone: 410-502-1477
Fax: 410-502-1419

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Background

Dr. Junghoon Lee is an assistant professor of radiation oncology and molecular radiation sciences at the Johns Hopkins University School of Medicine and an assistant research professor of electrical and computer engineering at the Johns Hopkins University Whiting School of Engineering.

Among other projects, his team is currently working on an intraoperative image-guidance system for dynamic dosimetry in prostate brachytherapy.

Dr. Lee received his B.S. in electrical engineering and his M.S. in biomedical engineering in 1997 and 1999, respectively, from Seoul National University in Seoul, Republic of Korea. He earned his Ph.D. in electrical and computer engineering from Purdue University in West Lafayette, Indiana in 2006.

From 1996 to 1999 he was a research assistant in the Artificial Heart Lab at Seoul National University, where he developed the telemetry system and the controller for the total artificial heart. From 1997 to 1998 he was a visiting researcher at the Electronics and Telecommunication Research Institute (ETRI) in Daejeon, Korea, where he designed ASIC layout for the totally implantable artificial heart internal controller and telemetry unit.

In 1998, he was a research assistant in the Department of Radiology at Seoul National University, where he conducted research on image-guided neurosurgery and the total artificial heart virtual surgery. From 1999 to 2002 he was a medical engineering officer at the Armed Forces Masan Hospital in Masan, Korea and at the 2nd Logistics Support Command in Euijungboo, Korea. From 2002 to 2007 he was a research assistant at Purdue University, where he conducted research on a statistical approach for simultaneous 3-D reconstructions and classification of multiple types of viruses from cryo-electron microscopy data.

In 2007, he joined the Department of Electrical and Computer Engineering and the NSF Engineering Research Center for Computer-Integrated Surgical Systems and Technology at Johns Hopkins as a postdoctoral fellow, and continued to work as an associate research scientist from January 2009 to October 2010.

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Titles

  • Assistant Professor of Radiation Oncology and Molecular Radiation Sciences

Education

Degrees

  • B.S., Seoul National University (Korea) (1997)
  • M.S., Seoul National University (Korea) (1999)
  • Ph.D., Purdue University (Indiana) (2006)

Research & Publications

Research Summary

The scope of Dr. Lee’s research includes: statistical signal and image processing and inverse problems; pattern recognition and classification, computer vision, and nonlinear optimization; image reconstruction, registration, and segmentation; and image-guided surgery and radiation therapy.

His current projects include:

  • Intraoperative image-guidance system for dynamic dosimetry in prostate brachytherapy (NCI, Acoustic MedSystems, RUF)
  • 4-D MRI-based tongue motion analysis after tongue cancer surgery (NCI)
  • Hardware-accelerated image registration and dose calculation for adaptive radiation therapy (NCI)
  • Evaluation of tumor motion management strategies in radiotherapy using 4-D MRI (NCI)
  • Multi-modal image registration by PROXI image synthesis (NIBIB)
  • An eScience program for the advancement of care in oncology – imaging as a biomarker and big data analysis (Toshiba)
  • Advanced cone-beam CT reconstruction incorporating prior CT images in radiotherapy (Elekta)

Selected Publications

  1. Xing F, Woo J, Lee J, Murano EZ, Stone M, Prince JL. "Analysis of 3D tongue motion from tagged and cine MR images" (submitted).
  2. Li W, Plishker W, Zaki G, Lee J, Quon H, Wong J, Shekhar R. "Quantitative evaluation of GPU-accelerated deformable image registration of CT and CBCT in head and neck cancer radiation therapy" (in revision).
  3. Lee J, Woo J, Xing F, Murano EZ, Stone M, Prince JL. "Semi-automatic segmentation for 3D motion analysis of the tongue with dynamic MRI." Comput Med Imaging Graph. 2014 Dec;38(8):714-24. doi: 10.1016/j.compmedimag.2014.07.004. Epub 2014 Aug 1.
  4. Woo J, Lee J, Murano E, Xing F, Al-Talib M, Stone M, Prince JL. "A high-resolution atlas statistical model of the vocal tract from structural MRI." Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization. 2014:1-14 (published online first).
  5. Kuo N, Dehghan E, Deguet A, Mian OY, Le Y, Burdette EC, Fichtinger G, Prince JL, Song DY, Lee J. "An image-guidance system for dynamic dose calculation in prostate brachytherapy using ultrasound and fluoroscopy." Med Phys. 2014 Sep;41(9):091712. doi: 10.1118/1.4893761.
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