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Patricia Ann Ramaley Brunker, MD

Assistant Professor of Pathology
Main Location

The Johns Hopkins Hospital

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  • Assistant Professor of Pathology



Research Interests

Alloimmunization; Transfusion medicine


Dr. Patricia Brunker is an assistant professor of pathology at the Johns Hopkins University School of Medicine. Her area of clinical expertise is transfusion medicine.

Dr. Brunker’s research explores the genetics of the basis of alloimmunization. These projects include the evaluation of rapid-responder and non-responder status in pregnancy and family studies of alloimmunization including microchimerism analysis.

Dr. Brunker received her medical degree from Brown University Medical School. She completed her residency at Brigham and Women’s Hospital in anatomic and clinical pathology and performed a fellowship in transfusion medicine at The Johns Hopkins Hospital and another in the Credentialing Services Section of the National Institutes of Health.

Dr. Brunker is certified in transfusion medicine and anatomic and clinical pathology by the American Board of Pathology.


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Additional Resources +
  • Education +


    • Brown University Medical School (Providence RI ) (2003)


    • Brigham and Women's Hospital / Anatomic and Clinical Pathology (Boston MA ) (2008)


    • National Institutes of Health - Credentialing Services Section / Transfusion Medicine (Bethesda MD ) (2012)
    • Johns Hopkins University School of Medicine / Transfusion Medicine (Baltimore MD ) (2009)


    • Transfusion Med, American Board of Pathology - Pathology (2010)
    • Anatomic & Clinical Pathology, American Board of Pathology (2008)
  • Research & Publications +

    Research Summary

    Dr. Brunker is using molecular characterization of patients and blood products to inform a patient-centered and individualized approach to transfusion medicine.

    Projects in this area include increased utilization and outcomes research in molecular testing, including weak and partial Rh testing, cell-free, fetal DNA and real-time PCR. Dr. Brunker evaluates rapid-responder and non-responder status in pregnancy and also conducts family studies of alloimmunization, including microchimerism analysis, in order to gain a better understanding of the genetics of the basis of alloimmunization.

    Selected Publications

    1. Brunker, PA. “Chimerism in transfusion medicine.” Chimerism, 4(4). 2013.
    2. Brunker, PA, Flegel, WA. “Scianna: the lucky 13th blood group system.” Immunohematology/American Red Cross. 27(2), 41. 2011.
    3. Leider, JP, Brunker, PA, Ness, PM. “Convalescent transfusion for pandemic influenza: preparing blood banks for a new plasma product?” Transfusion. 50(6), 1384-1398. 2010.
    4. Ramaley, PA, French, N, Kaleebu, P, Gilks, C, Whitworth, J, Hill, AV. “HIV in Africa: chemokine-receptor genes and AIDS risk.” Nature. 417(6885), 140-140. 2002.
    5. Hellier, S, Frodsham, AJ, Hennig, BJ, Klenerman, P, Knapp, S, Ramaley, P, Satsangi J, Wright M, Zhang L, Thomas HC, Thursz M, Hill AV. “Association of genetic variants of the chemokine receptor CCR5 and its ligands, RANTES and MCP-2, with outcome of HCV infection.” Hepatology, 38(6), 1468-1476. 2003.
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    The Johns Hopkins Hospital
    600 N. Wolfe Street
    Sheikh Zayed Tower
    Baltimore, MD 21287
    Phone: 410 614 0205
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    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    Baltimore, MD 21224
    Phone: 410 614 0205
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    • Pathology

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