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Photo of Dr. Mahendra Damarla

Mahendra Damarla, M.D.

Assistant Professor of Medicine

Male

Appointment Phone

410-550-5864

Main Location

Johns Hopkins Bayview Medical Center

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Assistant Professor of Medicine

Centers & Institutes

Departments

Locations

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-5864

4940 Eastern Avenue
Baltimore, MD 21224 map

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-3467

601 N. Caroline Street
Baltimore, MD 21287 map

The Johns Hopkins Hospital

Appointment Phone: 410-955-3467

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

Expertise

Acute Lung Injury, Pulmonary Disease and Critical Care Medicine

Research Interests

Vascular biology

Biography

Dr. Mahendra Damarla is an assistant professor of medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include acute lung injury, pulmonary disease and critical care medicine. 

Dr. Damarla earned his M.D. from the University of Louisville School of Medicine. He completed his residency at St. Elizabeth Medical Center and performed a fellowship in pulmonary medicine at Johns Hopkins.

His research interests include vascular biology.

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    Additional Information

  • Education +

    Degrees

    • University of Louisville School of Medicine / MD (2001)

    Residencies

    • St Elizabeth's Medical Center / Internal Medicine (2005)

    Fellowships

    • Johns Hopkins University School of Medicine / Pulmonary Medicine (2008)

    Certifications

    • American Board of Internal Medicine / Critical Care Medicine (2012)
    • American Board of Internal Medicine / Pulmonary Disease (2009)
  • Research & Publications +

    Selected Publications View all on PubMed

    Kim BS, Serebreni L, Fallica J, Hamdan O, Wang L, Johnston L, Kolb T, Damarla M, Damico R, Hassoun PM. "Cyclin-dependent kinase five mediates activation of lung xanthine oxidoreductase in response to hypoxia." PLoS One. 2015 Apr 1;10(4):e0124189. doi: 10.1371/journal.pone.0124189. eCollection 2015.

    Hikmat F, Pearse DB, Damarla M. "A presentation of massive hemoptysis in a patient with Churg-Strauss syndrome." Can Respir J. 2014 November/December;21(6):337-340. Epub 2014 Sep 25.

    Fallica J, Boyer L, Kim B, Serebreni L, Varela L, Hamdan O, Wang L, Simms T, Damarla M, Kolb TM, Bucala R, Mitzner W, Hassoun PM, Damico R. "Macrophage migration inhibitory factor is a novel determinant of cigarette smoke-induced lung damage." Am J Respir Cell Mol Biol. 2014 Jul;51(1):94-103. doi: 10.1165/rcmb.2013-0371OC.

    Aggarwal NR, Chau E, Garibaldi BT, Mock JR, Sussan T, Rao K, Rao K, Menon AG, D'Alessio FR, Damarla M, Biswal S, King LS, Sidhaye VK. "Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium." Tissue Barriers. 2013 Oct 1;1(4):e25248. doi: 10.4161/tisb.25248. Epub 2013 Jun 3.

    Damarla M, Parniani AR, Johnston L, Maredia H, Serebreni L, Hamdan O, Sidhaye VK, Shimoda LA, Myers AC, Crow MT, Schmidt EP, Machamer CE, Gaestel M, Rane MJ, Kolb TM, Kim BS, Damico RL, Hassoun PM. "Mitogen-activated protein kinase-activated protein kinase 2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3." Am J Respir Cell Mol Biol. 2014 May;50(5):932-41. doi: 10.1165/rcmb.2013-0361OC.

    Damarla M, Parniani AR, Johnston L, Maredia H, Serebreni L, Hamdan O, Sidhaye VK, Shimoda LA, Myers AC, Crow MT, Schmidt EP, Machamer CE, Gaestel M, Rane MJ, Kolb TM, Kim BS, Damico RL, Hassoun PM. MK2 Mediates Apoptosis During Lung Vascular Permeability by Regulating Movement of Cleaved Caspase 3. Am J Respir Cell Mol Biol. 2013 Dec 4. [Epub ahead of print] PMID: 24304496

    Kim BS, Serebreni L, Hamdan O, Wang L, Parniani A, Sussan T, Scott Stephens R, Boyer L, Damarla M, Hassoun PM, Damico R. Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis. Free Radic Biol Med. 2013 Jul;60:336-46. doi: 10.1016/j.freeradbiomed.2013.01.023. Epub 2013 Feb 4. PMID: 23380026

    Shah NG, Tulapurkar ME, Damarla M, Singh IS, Goldblum SE, Shapiro P, Hasday JD. Febrile-range hyperthermia augments reversible TNF-α-induced hyperpermeability in human microvascular lung endothelial cells. Int J Hyperthermia. 2012;28(7):627-35. doi: 10.3109/02656736.2012.690547. Epub 2012 Jul 26. PMID: 22834633

    Rentsendorj O, Damarla M, Aggarwal NR, Choi JY, Johnston L, D'Alessio FR, Crow MT, Pearse DB. Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2011 Aug;301(2):L161-70. doi: 10.1152/ajplung.00073.2011. Epub 2011 May 13. PMID: 21571906

    Damico R, Simms T, Kim BS, Tekeste Z, Amankwan H, Damarla M, Hassoun PM. p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor. Am J Respir Cell Mol Biol. 2011 Mar;44(3):323-32. doi: 10.1165/rcmb.2009-0379OC. Epub 2010 May 6. PMID: 20448056

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