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Photo of Dr. Young Kim

Young Jun Kim, MD PhD

Associate Professor of Otolaryngology-Head and Neck Surgery
Male
Appointment Phone

410-550-0460

Main Location

Johns Hopkins Bayview Medical Center

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Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-0773 (7a.m. to 6p.m., EST, Mon-Fri)

Learn more about our international patient services »

Titles

  • Associate Professor of Otolaryngology-Head and Neck Surgery
  • Associate Professor of Oncology

Centers & Institutes

  • Head and Neck Cancer Center
  • Sidney Kimmel Comprehensive Cancer Center

Expertise

Airway Disorders, Ear, Nose, and Throat, Head and Neck Cancers, Head and Neck Surgery, Laryngeal Disorders, Laryngeal Surgery, Nasal Reconstruction, Otolaryngology, Parathyroid Disorders, Parathyroid Surgery, Salivary Gland Disorders, Schwannomas of the Head and Neck, Skin Cancer, Thyroid Disorders, Thyroid Parathyroid, Thyroid Surgery

Research Interests

Development of immunotherapeutic treatments for head and neck malignancies; Tumor Immunology

Biography

Dr. Young Kim received his MD and PhD at University of California, San Diego, and completed his clinical training at University of California, Los Angeles.

His clinical interests include the medical and surgical management of head and neck tumor/cancer, thyroid/parathyroid tumors, and salivary gland tumors.

He also specializes in complex airway management and nasal reconstruction. He is currently the principle investigator of  an NIH funded lab that is focused on the development of translational cancer vaccines.

His lab is focused on tumor immunology and the development of novel immunotherapeutic strategies for cancer patients. Within the tumor microenvironment, we are studying the cross-talk between the tumor cells and the tumor infiltrating lymphocytic and myeloid cells.

At the molecular level, we found that STAT3 signaling in both lymphocytic and myeloid cells can induce immunosuppressive microenvironment, and we are actively studying the downstream mediators of this important phenotype. We have also developed novel cancer vaccines that are ideally suited to be combined with immune checkpoint blockade antibodies to reverse the immunosuppressive tumor microenvironment.

Languages

  • English
  • Korean

Memberships

1. American Academy Otolaryngology-Head & Neck Surgery
2. American Head & Neck Society
3. American College of Surgeons, Fellow

Additional Resources

Additional Resources +
  • Education +

    Training

    • University of California San Diego School of Medicine ( La Jolla CA ) (1999)

    Residencies

    • UCLA Medical Center/Otolaryngology ( Los Angeles CA ) (2005)

    Certifications

    • General, American Board of Otolaryngology-Otolaryngology (2007)
  • Research & Publications +

    Selected Publications

    1.     Shu CJGuo SKim YJShelly SMNijagal ARay PGambhir SSRadu CGWitte ON. Visualization of a primary anti-tumor immune response by positron emission tomography. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17412-7. PMID: 16293690

    2.     Kim YJ, Smith J, Sercarz JA, Head C, Abemayor E, Blackwell K. Fixation of Mandibular Osteotomies: Comparison of Locking and Nonlocking Hardware. Head Neck 2007 May; 29:453-457.

    3.     Chu, E, Kim YJ. Preoperative Evaluation in Laryngeal Tumor. Otolaryngol Clin North Am. 2008; 41(4): 673-95. 

    4.     Geller K, Kim YJ, Koempel J, Anderson KD. Surgical management of type III and IV laryngotracheoesophageal clefts: The three-layered approach. Int J Pediatr Otorhinolaryngol. 2010 Jun;74(6):652-7. PMID: 20416955

     

    1. Albesiano E, Davis M, See AP, Han J, Lim M, Pardoll DP, Kim YJ. Immunological Consequences of Signal Transducers and Activators of Transcription 3 Activation in Human Squamous Cell Carcinoma. Cancer Research. 2010 Aug 70(16):p6467-76. PMID: 20682796
    2. Davis M, FuJ, Vasquez D, Albesiano E, Pardoll D, Kim YJ.  TLR4 Agonist Enhanced GVAX - TEGVAX - Improves the Anti-tumor Response In Vivo. Clinical Cancer Research. 2011 Jun; 17(12):3984-92. PMID: 21543518
    3. Dang EV, Barbi J, Yang HY, Jinasena D, Yu H, Zheng Y, Bordman Z, Fu J, Kim YJ, Luo W, Yen HR, Shimoda L, Topalian S, Semenza GL, Dang CV, Pardoll D, Pan F. Control of the Th17/Treg Balance by Hypoxia-inducible Factor 1a. Cell. 2011 Sep; 146(5): 772-84. PMID: 21871655
    4. See AP, Han JE, Phallen J, Binder Z, Gallia G, Pan F, Jinasena D, Jackson C, Belcaid Z, Jeong SJ, Gottschalk C, Zeng J, Ruzevick J, Nicholas S, Kim YJ, Albesiano E, Pardoll D, Lim M. The role of STAT3 activation in modulating the immune microenvironment of GBM. J Neurooncol. 2012 Dec; 110(3): 359-68. PMID: 23096132.
    5. Vasquez-Dunddel D,Pan F,Zeng Q, Gorbounov M, Albesiano E, Fu J, Blosser R, Tam A, Bruno T, Zhang H, Pardoll D, Kim YJ.STAT3 Regulates Arginase-1 in MDSC from Cancer Patients. J Clinical Investigation. 123 (4): 1580-1589.
    6. Malm I, Olcott C, Chan J, Loyo M, Kim YJ. Congenital Agenesis of the Common Carotid Artery Associated with an Ectopic Parathyroid Adenoma Mimicking a Carotid Body Tumor. Am J Oto. 34(5):553-5. 
  • Academic Affiliations & Courses +
  • Activities & Honors +
  • Videos & Media +
  • Upcoming Events +
  • Contact & Locations +

    Locations

    Johns Hopkins Bayview Medical Center
    4940 Eastern Avenue
    A Room A595
    Baltimore, MD 21224
    Phone: 410-550-0460
    Appointment Phone: 410-550-0460
    Location Map
    Johns Hopkins Medicine - White Marsh
    4924 Campbell Boulevard
    White Marsh, MD 21236
    Appointment Phone: 410-550-0460
    Location Map

    Department/Division

    • Otolaryngology - Head and Neck Surgery - Division of Head and Neck Surgery

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