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Photo of Dr. Christopher Romero

Christopher Joseph Romero, M.D.

Assistant Professor of Pediatrics

Male  | Languages: English, Spanish

Appointment Phone

410-955-2000

Main Location

Johns Hopkins Pediatric Specialty Clinic

Out-of-State & International Patients +
Out of State Patients

Call 410-464-6641 (8a.m. to 6p.m., EST, Mon-Fri)

Learn more about our out-of-state patient services »

International Patients

Call +1-410-502-7683 (7a.m. to 6p.m., EST, Mon-Fri)

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Titles

  • Assistant Professor of Pediatrics

Centers & Institutes

Departments

  • Pediatrics - Endocrinology

Locations

Johns Hopkins Pediatric Specialty Clinic

Appointment Phone: 410-955-2000

200 N. Wolfe Street
Rubenstein Child Health
Baltimore, MD 21287 map

The Johns Hopkins Hospital

Appointment Phone: 410-955-2000

600 N. Wolfe Street
Sheikh Zayed Tower
Baltimore, MD 21287 map

Expertise

Pediatric Endocrinology

Research Interests

Molecular basis of hypopituitarism, Insulin-like growth factor 1 regulation of growth and metabolism, Pituitary growth, Thyroid, Calcium/bone, Puberty abnormalities, Diabetes

Biography

Dr. Christopher Romero is an assistant professor of pediatrics at the Johns Hopkins University School of Medicine. His areas of clinical expertise include pituitary growth, thyroid problems, calcium and bone issues, puberty abnormalities, and diabetes.

Dr. Romero received his undergraduate degree in chemistry and English from Rutgers University, followed by a master’s degree in science at Hahnemann University. He earned his medical degree at MCP-Hahnemann University School of Medicine, now Drexel University College of Medicine, and completed a residency in pediatrics at UCSF-Fresno. Dr. Romero performed his fellowship in pediatric endocrinology at the Johns Hopkins University School of Medicine and joined the faculty in 2008.

His research focuses on the study of pituitary hormone deficiency in children and the regulation of the somatotroph. He recruits children with multiple pituitary hormone deficiencies and studying various pituitary transcription factors known to be important in pituitary development. The goal is to help identify genetic mutations using novel technology such as next generation sequencing that may be responsible for pituitary disease in children with hormone deficiency with unknown cause.

Dr. Romero serves as an advisory board member for the Johns Hopkins Center for Salud/Health and Opportunity for Latinos (Centro Sol) and as a member of the Johns Hopkins Diversity Leadership Council. He received the Human Growth Foundation Award from the Pediatric Endocrine Society and is a member of the Society for Pediatric Research, the American Academy of Pediatrics, the Pediatric Endocrine Society and the Endocrine Society.

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    Additional Information

  • Education +

    Degrees

    • MCP Hahnemann University / MD (2001)

    Residencies

    • Central California Faculty Medical Group / Pediatrics (2005)
    • Children's Hospital Central California / Pediatrics (2005)

    Fellowships

    • Johns Hopkins University School of Medicine / Pediatric Endocrinology (2008)
  • Research & Publications +

    Research Summary

    Dr. Romero focuses his efforts on the study of pituitary hormone deficiency in children and the regulation of the somatotroph. One area of his research involves recruiting children with multiple pituitary hormone deficiencies and studying various pituitary transcription factors known to be important in pituitary development. The goal is to help identify genetic mutations using novel technology such as next generation sequencing that may be responsible for pituitary disease in children with hormone deficiency with unknown cause.

    In addition, Dr. Romero’s research has led to the development of novel mouse model systems that allow him to study the regulation of the somatotroph, which is important in the production of growth hormone.

    Selected Publications View all on PubMed

    Avtanski D, Novaira HJ, Wu S, Romero CJ, Kineman R, Luque RM, Wondisford F, Radovick S. "Both estrogen receptor α and β stimulate pituitary GH gene expression." Mol Endocrinol. 2014 Jan;28(1):40-52. doi: 10.1210/me.2013-1245. Epub 2013 Jan 1.

    Iwama S, Welt CK, Romero CJ, Radovick S, Caturegli P. "Isolated prolactin deficiency associated with serum autoantibodies against prolactin-secreting cells." J Clin Endocrinol Metab. 2013 Oct;98(10):3920-5. doi: 10.1210/jc.2013-2411. Epub 2013 Aug 12. Erratum in: J Clin Endocrinol Metab. 2013 Dec;98(12):4992.

    Pine-Twaddell E, Romero CJ, Radovick S. "Vertical transmission of hypopituitarism: critical importance of appropriate interpretation of thyroid function tests and levothyroxine therapy during pregnancy." Thyroid. 2013 Jul;23(7):892-7. doi: 10.1089/thy.2012.0332. Epub 2013 Jun 21.

    Romero CJ, Pine-Twaddell E, Sima DI, Miller RS, He L, Wondisford F, Radovick S. "Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions." Mol Cell Biol. 2012 Nov;32(21):4258-69. doi: 10.1128/MCB.00171-12. Epub 2012 Aug 13.

    Gorbenko Del Blanco D, Romero CJ, Diaczok D, de Graaff LC, Radovick S, Hokken-Koelega AC. "A novel OTX2 mutation in a patient with combined pituitary hormone deficiency, pituitary malformation, and an underdeveloped left optic nerve." Eur J Endocrinol. 2012 Sep;167(3):441-52. doi: 10.1530/EJE-12-0333. Epub 2012 Jun 19.

  • Academic Affiliations & Courses +
  • Activities & Honors +

    Honors

    • Human Growth Foundation Award, Pediatric Endocrine Society, 2009

    Memberships

    • Society for Pediatric Research, 2014
    • Fellow of the American Academy of Pediatrics, 2005
    • Pediatric Endocrine Society, 2005
    • The Endocrine Society, 2005
    • American Academy of Pediatrics, 2001 - 2008
    • Fresno Madera Medical Society, 2004 - 2005

    Professional Activities

    • Advisory Board Member and Member of Strategic Planning, Johns Hopkins Center for Salud/Health and Opportunity for Latinos (Centro Sol), 2013
    • Co-founder and Committee Member, Latino Alliance, 2013
    • Diversity Leadership Council, Johns Hopkins University, 2012
    • Manuscript reviewer, PLOS One, 2013
  • Videos & Media +
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